Published in Curr Treat Options Oncol on September 01, 2014
Treatment of IBD: where we are and where we are going. Am J Gastroenterol (2014) 1.02
Modified Pulsatilla decoction attenuates oxazolone-induced colitis in mice through suppression of inflammation and epithelial barrier disruption. Mol Med Rep (2016) 0.77
Natural product HTP screening for antibacterial (E.coli 0157:H7) and anti-inflammatory agents in (LPS from E. coli O111:B4) activated macrophages and microglial cells; focus on sepsis. BMC Complement Altern Med (2016) 0.76
Deoxyschizandrin suppresses dss-induced ulcerative colitis in mice. Saudi J Gastroenterol (2016) 0.75
Recent Trends in Pharmacological Activity of Alkaloids in Animal Colitis: Potential Use for Inflammatory Bowel Disease. Evid Based Complement Alternat Med (2017) 0.75
Systems Pharmacological Approach of Pulsatillae Radix on Treating Crohn's Disease. Evid Based Complement Alternat Med (2017) 0.75
Randomised clinical trial: herbal extract HMPL-004 in active ulcerative colitis - a double-blind comparison with sustained release mesalazine. Aliment Pharmacol Ther (2010) 2.20
Systemic corticosteroid therapy--side effects and their management. Br J Ophthalmol (1998) 1.81
Colorectal cancer in inflammatory bowel disease: what is the real magnitude of the risk? World J Gastroenterol (2012) 1.63
Andrographolide attenuates inflammation by inhibition of NF-kappa B activation through covalent modification of reduced cysteine 62 of p50. J Immunol (2004) 1.58
Placebo controlled evaluation of Xilei San, a herbal preparation in patients with intractable ulcerative proctitis. J Gastroenterol Hepatol (2012) 1.52
Randomized trials in alternative/complementary medicine. QJM (2002) 1.47
Review article: complementary and alternative therapies for inflammatory bowel disease. Aliment Pharmacol Ther (2006) 1.44
On the use of herbal medicines in management of inflammatory bowel diseases: a systematic review of animal and human studies. Dig Dis Sci (2008) 1.22
Andrographis paniculata extract (HMPL-004) for active ulcerative colitis. Am J Gastroenterol (2012) 1.10
Systematic review: the efficacy of herbal therapy in inflammatory bowel disease. Aliment Pharmacol Ther (2013) 1.08
A phase I study of the chinese herbal medicine PHY906 as a modulator of irinotecan-based chemotherapy in patients with advanced colorectal cancer. Clin Colorectal Cancer (2011) 1.05
Antioxidant and anti-inflammatory activities of the plant Andrographis paniculata Nees. Immunopharmacol Immunotoxicol (2006) 1.01
Use of complementary medicine in pediatric patients with inflammatory bowel disease: results from a multicenter survey. J Pediatr Gastroenterol Nutr (2009) 1.01
Adverse skin reactions to anti-TNF-alpha monoclonal antibody therapy. Dermatology (2003) 1.01
A Chinese herb Tripterygium wilfordii Hook F in the treatment of rheumatoid arthritis: mechanism, efficacy, and safety. Rheumatol Int (2011) 0.98
Preparative isolation and purification of alkannin/shikonin derivatives from natural products by high-speed counter-current chromatography. Biomed Chromatogr (2009) 0.95
The efficacy of Chinese herbal medicine as an adjunctive therapy for colorectal cancer: a systematic review and meta-analysis. Complement Ther Med (2012) 0.94
[Screening on alkaloid of Sophora alopecuraides against adenocarcinoma of colon cell line SW620 in vitro]. Zhong Yao Cai (2008) 0.94
Cyclooxygenase inhibitory and antioxidant compounds from the mycelia of the edible mushroom Grifola frondosa. J Agric Food Chem (2002) 0.91
Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives. J Gastroenterol (2013) 0.91
An old herbal medicine with a potentially new therapeutic application in inflammatory bowel disease. Int J Clin Exp Med (2011) 0.90
Efficacy of T2 in active Crohn's disease: a prospective study report. Dig Dis Sci (2007) 0.90
Targeted cancer therapies: the future of cancer treatment. Acta Biomed (2012) 0.90
Spica prunellae promotes cancer cell apoptosis, inhibits cell proliferation and tumor angiogenesis in a mouse model of colorectal cancer via suppression of stat3 pathway. BMC Complement Altern Med (2013) 0.87
Inhibitory effects of β,β-dimethylacrylshikonin on hepatocellular carcinoma in vitro and in vivo. Phytother Res (2011) 0.86
[Randomized controlled study on effect of Quxie capsule on the median survival time and qualify of life in patients with advanced colorectal carcinoma]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2008) 0.86
Effect of traditional Chinese medicinal enemas on ulcerative colitis of rats. World J Gastroenterol (2004) 0.86
Cohort study on the effect of a combined treatment of traditional Chinese medicine and Western medicine on the relapse and metastasis of 222 patients with stage II and III colorectal cancer after radical operation. Chin J Integr Med (2008) 0.85
Complementary and alternative medicine in patients with inflammatory bowel disease: the results of a population-based inception cohort study (IBSEN). J Crohns Colitis (2011) 0.85
Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivo. Life Sci (2012) 0.85
Alternative medicine products as a novel treatment strategy for inflammatory bowel disease. Am J Chin Med (2008) 0.84
Grifola frondosa water extract alleviates intestinal inflammation by suppressing TNF-alpha production and its signaling. Exp Mol Med (2010) 0.84
n-of-1 randomized controlled trials: an opportunity for complementary and alternative medicine evaluation. J Altern Complement Med (2004) 0.84
Impact of COX-2, IL-1β, TNF-α, IL-4 and IL-10 on the process of carcinogenesis in the large bowel. Pol J Pathol (2012) 0.84
Characterization of chromosomal instability in murine colitis-associated colorectal cancer. PLoS One (2011) 0.82
Effects of Changtai granules, a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats. World J Gastroenterol (2005) 0.82
Colon carcinogenesis in inflammatory bowel disease. Inflamm Bowel Dis (1995) 0.82
Comparison of Xilei-san, a Chinese herbal medicine, and dexamethasone in mild/moderate ulcerative proctitis: a double-blind randomized clinical trial. J Altern Complement Med (2013) 0.82
Kui jie qing in the treatment of chronic non-specific ulcerative colitis. J Tradit Chin Med (1997) 0.81
Effect of β,β-dimethylacrylshikonin on inhibition of human colorectal cancer cell growth in vitro and in vivo. Int J Mol Sci (2012) 0.81
Regulation of apoptotic effects by erythrocarpine E, a cytotoxic limonoid from Chisocheton erythrocarpus in HSC-4 human oral cancer cells. PLoS One (2011) 0.81
Dietary uptake of Wedelia chinensis extract attenuates dextran sulfate sodium-induced colitis in mice. PLoS One (2013) 0.81
Inhibition of proteases as a novel therapeutic strategy in the treatment of metabolic, inflammatory and functional diseases of the gastrointestinal tract. Drug Discov Today (2013) 0.80
[Study on mass spectra of alkaloids from Sophora alopecuroides L]. Yao Xue Xue Bao (1987) 0.79
[Efficacy of polyglycosides of Tripterygium wilfordii in preventing postoperative recurrence of Crohn disease]. Zhonghua Wei Chang Wai Ke Za Zhi (2009) 0.78
Effects of Shikunshito-Kamiho on fecal enzymes and formation of aberrant crypt foci induced by 1,2-dimethylhydrazine. Biol Pharm Bull (2001) 0.78
[Maintenance effect of polyglycosides of Tripterygium wilfordii on remission in postoperative Crohn disease]. Zhonghua Wei Chang Wai Ke Za Zhi (2009) 0.78
[Experimental study on treatment of immune ulcerative colitis in mice by Changlu Enema]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2007) 0.77
Submerged culture mycelium and broth of Grifola frondosa improve glycemic responses in diabetic rats. Am J Chin Med (2008) 0.76
[Cohort study on fuzheng capsule and quxie capsule in reducing relapse and metastasis of cancer in patients with stage II and III colorectal carcinoma after operation]. Zhongguo Zhong Xi Yi Jie He Za Zhi (2006) 0.76
Treatment of inflammatory bowel disease with Chinese drugs administered by both oral intake and retention enema. Chin J Integr Med (2010) 0.76
Review article: the role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases. Naunyn Schmiedebergs Arch Pharmacol (2014) 1.17
Opioid receptors and their ligands. Curr Top Med Chem (2004) 1.14
The past, present and future of gastroenterology in Europe and worldwide. United European Gastroenterol J (2015) 1.06
Distribution, function and physiological role of melatonin in the lower gut. World J Gastroenterol (2011) 1.01
The role of morphine in regulation of cancer cell growth. Naunyn Schmiedebergs Arch Pharmacol (2011) 1.00
Characterization and distribution of NKD, a receptor for Drosophila tachykinin-related peptide 6. Peptides (2008) 0.94
Quantitative assays for anti-aquaporin-4 antibody with subclass analysis in neuromyelitis optica. Mult Scler (2012) 0.93
Non-specific abdominal pain and air pollution: a novel association. PLoS One (2012) 0.92
Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives. J Gastroenterol (2013) 0.91
Effects of berberine in the gastrointestinal tract - a review of actions and therapeutic implications. Am J Chin Med (2014) 0.89
Natural and synthetic α-methylenelactones and α-methylenelactams with anticancer potential. Drug Discov Today (2012) 0.88
A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. Neuropharmacology (2013) 0.86
Enzymatic degradation of endomorphins. Peptides (2008) 0.84
Role of transient receptor potential channels in intestinal inflammation and visceral pain: novel targets in inflammatory bowel diseases. Inflamm Bowel Dis (2015) 0.84
The influence of opioids on urokinase plasminogen activator on protein and mRNA level in MCF-7 breast cancer cell line. Chem Biol Drug Des (2009) 0.83
Opioid-induced regulation of mu-opioid receptor gene expression in the MCF-7 breast cancer cell line. Biochem Cell Biol (2008) 0.82
Functional comparison of two evolutionary conserved insect neurokinin-like receptors. Peptides (2006) 0.82
Characterization of the effects of opiorphin and sialorphin and their analogs substituted in position 1 with pyroglutamic acid on motility in the mouse ileum. J Pept Sci (2013) 0.82
Synthesis and biological evaluation of novel peripherally active morphiceptin analogs. Peptides (2010) 0.82
Comparison of antagonist activity of spantide family at human neurokinin receptors measured by aequorin luminescence-based functional calcium assay. Regul Pept (2005) 0.81
Nociceptin / orphanin FQ (NOP) receptors as novel potential target in the treatment of gastrointestinal diseases. Curr Drug Targets (2013) 0.81
Synthesis and biological evaluation of cyclic endomorphin-2 analogs. Peptides (2009) 0.81
Inhibiting roles of berberine in gut movement of rodents are related to activation of the endogenous opioid system. Phytother Res (2013) 0.81
Orally administered novel cyclic pentapeptide P-317 alleviates symptoms of diarrhoea-predominant irritable bowel syndrome. J Pharm Pharmacol (2014) 0.81
Beneficial Effects of Probiotics, Prebiotics, Synbiotics, and Psychobiotics in Inflammatory Bowel Disease. Inflamm Bowel Dis (2015) 0.81
Endomorphin analogs. Curr Med Chem (2007) 0.80
Absorbable Versus Nonabsorbable Sutures for Skin Closure: A Meta-analysis of Randomized Controlled Trials. Ann Plast Surg (2016) 0.80
Inhibition of proteases as a novel therapeutic strategy in the treatment of metabolic, inflammatory and functional diseases of the gastrointestinal tract. Drug Discov Today (2013) 0.80
Anti-inflammatory and antinociceptive action of an orally available nociceptin receptor agonist SCH 221510 in a mouse model of inflammatory bowel diseases. J Pharmacol Exp Ther (2013) 0.80
Expression and physiology of opioid receptors in the gastrointestinal tract. Curr Opin Endocrinol Diabetes Obes (2016) 0.79
Enzymatic degradation studies of endomorphin-2 and its analogs containing N-methylated amino acids. Peptides (2005) 0.79
Platelet activity in the pathophysiology of inflammatory bowel diseases. Curr Drug Targets (2015) 0.79
Biological activity of endomorphin and [Dmt1]endomorphin analogs with six-membered proline surrogates in position 2. Bioorg Med Chem (2009) 0.79
The novel endomorphin degradation blockers Tyr-Pro-DClPhe-Phe-NH (EMDB-1) and Tyr-Pro-Ala-NH (EMDB-2) prolong endomorphin-2 action in rat ileum in vitro. Chem Biol Drug Des (2010) 0.79
Prevention and therapeutic strategies of thromboembolic events in patients with inflammatory bowel diseases: a report of three cases. Curr Drug Targets (2015) 0.79
Synthesis and biological activity of endomorphin-2 analogs incorporating piperidine-2-, 3- or 4-carboxylic acids instead of proline in position 2. Chem Biol Drug Des (2008) 0.79
Experimental colitis in mice is attenuated by topical administration of chlorogenic acid. Naunyn Schmiedebergs Arch Pharmacol (2015) 0.78
Polyphenol extract from evening primrose pomace alleviates experimental colitis after intracolonic and oral administration in mice. Naunyn Schmiedebergs Arch Pharmacol (2014) 0.78
Novel glycosylated endomorphin-2 analog produces potent centrally-mediated antinociception in mice after peripheral administration. Bioorg Med Chem Lett (2013) 0.78
Clinical relevance of serum aquaporin-4 antibody levels in neuromyelitis optica. Neurochem Res (2013) 0.78
Effect of potent endomorphin degradation blockers on analgesic and antidepressant-like responses in mice. Neuropharmacology (2011) 0.78
Opioid antagonist-induced regulation of the mu-opioid receptor expression in MCF-7 breast cancer cell line. Endocr Regul (2009) 0.77
Inhibition of trigemino-hypoglossal reflex in rats by oxytocin is mediated by mu and kappa opioid receptors. Brain Res (2005) 0.77
Synthesis and antinociceptive activity of cyclic endomorphin-2 and morphiceptin analogs. Biochem Pharmacol (2005) 0.77
Tenapanor hydrochloride for the treatment of constipation-predominant irritable bowel syndrome. Expert Opin Investig Drugs (2015) 0.76
Pharmacological properties of novel cyclic pentapeptides with µ-opioid receptor agonist activity. Med Chem (2014) 0.76
Synthesis and biological activity of N-methylated analogs of endomorphin-2. Bioorg Med Chem (2005) 0.76
[Endomorphins--endogenous ligands of the mu-opioid receptor]. Postepy Biochem (2009) 0.76
[Opioid receptors and their selective ligands]. Postepy Biochem (2006) 0.76
Binding of the new morphiceptin analogs to human MCF-7 breast cancer cells and their effect on growth. Regul Pept (2004) 0.76
Acid loading stimulates rat glomerular mesangial cells proliferation through Na(+)-H (+) exchanger isoform 1 (NHE1)-dependent pathway. Naunyn Schmiedebergs Arch Pharmacol (2013) 0.76
Kinetic studies of novel inhibitors of endomorphin degrading enzymes. Med Chem Res (2011) 0.75
Anemia of Chronic Disease and Iron Deficiency Anemia in Inflammatory Bowel Diseases: Pathophysiology, Diagnosis, and Treatment. Inflamm Bowel Dis (2016) 0.75
Synthesis and opioid activity of novel 6-substituted-6-demethoxy-ethenomorphinans. Bioorg Med Chem (2010) 0.75
Role of G protein-coupled orphan receptors in intestinal inflammation: novel targets in inflammatory bowel diseases. Inflamm Bowel Dis (2015) 0.75
Synthesis and opioid activity of novel 6-ketolevorphanol derivatives. Med Chem (2013) 0.75
Young Talent Group launches actions for young gastroenterologists by introducing the UEG Young GI Network. United European Gastroenterol J (2014) 0.75
Fat-soluble Vitamin Deficiencies and Inflammatory Bowel Disease: Systematic Review and Meta-Analysis. J Clin Gastroenterol (2017) 0.75
Structure-activity relationship, conformation and pharmacology studies of morphiceptin analogues--selective mu-opioid receptor ligands. Mini Rev Med Chem (2002) 0.75
Design, synthesis and pharmacological characterization of endomorphin analogues with non-cyclic amino acid residues in position 2. Basic Clin Pharmacol Toxicol (2009) 0.75
Silver and Other Metals in the Treatment of Gastrointestinal Diseases. Curr Med Chem (2015) 0.75
[Salvinorin A and related diterpenes--biological activity and potential therapeutic uses]. Postepy Biochem (2012) 0.75