Published in Ann Allergy Asthma Immunol on May 05, 2014
Urban Particulate Matter-Activated Human Dendritic Cells Induce the Expansion of Potent Inflammatory Th1, Th2, and Th17 Effector Cells. Am J Respir Cell Mol Biol (2016) 0.81
A Review of the CD4+ T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population. EC Microbiol (2015) 0.77
The influence of atopy and asthma on immune responses in inner-city adults. Immun Inflamm Dis (2016) 0.76
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol (1986) 35.41
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol (1989) 31.72
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med (1992) 11.90
Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med (2002) 9.14
Asthma. N Engl J Med (2001) 8.73
Lebrikizumab treatment in adults with asthma. N Engl J Med (2011) 8.07
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med (2009) 7.11
The eosinophil. Annu Rev Immunol (2006) 7.06
Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA (2002) 6.98
Cluster analysis and clinical asthma phenotypes. Am J Respir Crit Care Med (2008) 5.80
Dupilumab in persistent asthma with elevated eosinophil levels. N Engl J Med (2013) 5.29
Asthma: defining of the persistent adult phenotypes. Lancet (2006) 4.78
Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med (1999) 4.75
Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet (2008) 3.71
Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. J Allergy Clin Immunol (2011) 3.35
Associations of wheezing phenotypes in the first 6 years of life with atopy, lung function and airway responsiveness in mid-childhood. Thorax (2008) 3.25
Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage. Am Rev Respir Dis (1992) 2.89
Reslizumab for poorly controlled, eosinophilic asthma: a randomized, placebo-controlled study. Am J Respir Crit Care Med (2011) 2.80
The many paths to asthma: phenotype shaped by innate and adaptive immunity. Nat Immunol (2010) 2.74
Interleukin-10 regulation in normal subjects and patients with asthma. J Allergy Clin Immunol (1996) 2.55
T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma. J Allergy Clin Immunol (2009) 2.54
Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-gamma, IL-4, IL-10 and IL-13) in patients with allergic asthma. Clin Exp Immunol (2001) 2.39
An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children. Lancet (2005) 2.39
Comparison of childhood wheezing phenotypes in 2 birth cohorts: ALSPAC and PIAMA. J Allergy Clin Immunol (2011) 2.38
Heterogeneity of severe asthma in childhood: confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program. J Allergy Clin Immunol (2010) 2.27
Cytokines, allergy, and asthma. Curr Opin Allergy Clin Immunol (2005) 2.16
IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity. Am J Respir Crit Care Med (1996) 1.93
Clinical and epidemiologic phenotypes of childhood asthma. Am J Respir Crit Care Med (2014) 1.87
Asthma: clinical expression and molecular mechanisms. J Allergy Clin Immunol (2010) 1.84
Beyond atopy: multiple patterns of sensitization in relation to asthma in a birth cohort study. Am J Respir Crit Care Med (2010) 1.82
A large subgroup of mild-to-moderate asthma is persistently noneosinophilic. Am J Respir Crit Care Med (2012) 1.75
Interleukin-4, interferon-gamma and interleukin-5 in peripheral blood of children with moderate atopic asthma. Clin Exp Allergy (1997) 1.65
Total IgE levels and asthma prevalence in the US population: results from the National Health and Nutrition Examination Survey 2005-2006. J Allergy Clin Immunol (2009) 1.64
Th17 cells: new players in asthma pathogenesis. Allergy (2011) 1.64
Assessment of the Th1/Th2 paradigm in whole blood in atopy and asthma. Increased IFN-gamma-producing CD8(+) T cells in asthma. Am J Respir Crit Care Med (2000) 1.59
Atopy phenotypes in the Childhood Asthma Prevention Study (CAPS) cohort and the relationship with allergic disease: clinical mechanisms in allergic disease. Clin Exp Allergy (2013) 1.50
Regulatory T cells and asthma. Clin Exp Allergy (2009) 1.48
Increased serum IL-17 is an independent risk factor for severe asthma. Respir Med (2010) 1.29
Untangling asthma phenotypes and endotypes. Allergy (2012) 1.17
Narrative review: the role of Th2 immune pathway modulation in the treatment of severe asthma and its phenotypes. Ann Intern Med (2010) 1.13
Adaptive cytokine production in early life differentially predicts total IgE levels and asthma through age 5 years. J Allergy Clin Immunol (2011) 1.08
Polyclonal and allergen-induced cytokine responses in adults with asthma: resolution of asthma is associated with normalization of IFN-gamma responses. J Allergy Clin Immunol (2002) 0.99
Elucidation of asthma phenotypes in atopic teenagers through parallel immunophenotypic and clinical profiling. J Allergy Clin Immunol (2009) 0.98
Interleukin-4 and interferon-gamma production in atopic and non-atopic children with asthma. Clin Exp Allergy (1995) 0.96
Defective IL-10 expression and in vitro steroid-induced IL-17A in paediatric severe therapy-resistant asthma. Thorax (2013) 0.94
The relationship between early fever and allergic sensitization at age 6 to 7 years. J Allergy Clin Immunol (2004) 0.91
Pediatric asthma and development of atopy. Curr Opin Allergy Clin Immunol (2013) 0.90
Influence of early day-care exposure on total IgE levels through age 3 years. J Allergy Clin Immunol (2007) 0.88
Atopic phenotypes identified with latent class analyses at age 2 years. J Allergy Clin Immunol (2014) 0.88
Validation of novel wheeze phenotypes using longitudinal airway function and atopic sensitization data in the first 6 years of life: evidence from the Southampton Women's survey. Pediatr Pulmonol (2013) 0.88
Th17 immunity in children with allergic asthma and rhinitis: a pharmacological approach. PLoS One (2013) 0.87
Revising the immunological theories of asthma and allergy. Lancet (2005) 0.85
Cytokine production from peripheral whole blood in atopic and nonatopic asthmatics: relationship with blood and sputum eosinophilia and serum IgE levels. Allergy (2000) 0.84
Polyclonal and allergen-induced cytokine responses in children with elevated immunoglobulin E but no atopic disease. Clin Exp Allergy (2002) 0.83
Association of IL-5 cytokine production and in vivo IgE levels in infants and parents. J Allergy Clin Immunol (2007) 0.82
Type 2 immune responses in obese individuals with asthma. Am J Respir Crit Care Med (2013) 0.81
Race-specific Association of Caesarean-Section Delivery with Body Size at Age 2 Years. Ethn Dis (2016) 0.75
Allergic sensitization in American children of Middle Eastern ethnicity at age 2. Ann Allergy Asthma Immunol (2017) 0.75