Published in Oncotarget on May 15, 2014
Endocannabinoid system as a regulator of tumor cell malignancy - biological pathways and clinical significance. Onco Targets Ther (2016) 1.14
Cannabinoids as therapeutic agents in cancer: current status and future implications. Oncotarget (2014) 1.05
Sulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal model. Oncotarget (2014) 0.86
Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: novel anti-tumor mechanisms of Cannabidiol in breast cancer. Mol Oncol (2015) 0.81
Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells. Redox Biol (2016) 0.77
Fatty acid binding protein 5 promotes metastatic potential of triple negative breast cancer cells through enhancing epidermal growth factor receptor stability. Oncotarget (2015) 0.77
Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells. Oncotarget (2016) 0.75
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells. Cancer Biol Ther (2016) 0.75
The Fatty Acid Amide Hydrolase Inhibitor URB937 Ameliorates Radiation-Induced Lung Injury in a Mouse Model. Inflammation (2017) 0.75
Cancer statistics, 2013. CA Cancer J Clin (2013) 84.72
Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature (1990) 13.60
Molecular characterization of a peripheral receptor for cannabinoids. Nature (1993) 13.45
Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer (2003) 13.01
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature (1996) 8.99
The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev (2006) 6.80
Mammalian cyclin-dependent kinases. Trends Biochem Sci (2005) 5.54
Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim Biophys Acta (2006) 4.27
Cell migration in tumors. Curr Opin Cell Biol (2005) 3.88
FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR. Nature (2011) 3.18
Cannabinoids: potential anticancer agents. Nat Rev Cancer (2003) 2.87
Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer. FEBS J (2009) 2.42
Possible endocannabinoid control of colorectal cancer growth. Gastroenterology (2003) 1.89
Targeting the EGFR signaling pathway in cancer therapy. Expert Opin Ther Targets (2012) 1.85
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest (2011) 1.74
New insights into cyclins, CDKs, and cell cycle control. Semin Cell Dev Biol (2005) 1.70
A second fatty acid amide hydrolase with variable distribution among placental mammals. J Biol Chem (2006) 1.63
EGFR-mutated lung cancer: a paradigm of molecular oncology. Oncotarget (2010) 1.53
The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. Proc Natl Acad Sci U S A (1998) 1.53
Cannabinoid receptor agonist-induced apoptosis of human prostate cancer cells LNCaP proceeds through sustained activation of ERK1/2 leading to G1 cell cycle arrest. J Biol Chem (2006) 1.51
Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. Prostaglandins Leukot Essent Fatty Acids (2002) 1.48
Cell-cycle control and its watchman. Nature (1996) 1.44
Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production. Prostate (2003) 1.38
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. Mol Cancer Ther (2009) 1.36
Links between apoptosis, proliferation and the cell cycle. Br J Biomed Sci (2004) 1.36
Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy. Mol Cancer Ther (2011) 1.30
S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways. Cancer Res (2011) 1.25
Prostamides (prostaglandin-ethanolamides) and their pharmacology. Br J Pharmacol (2007) 1.23
Cannabinoids and cancer: pros and cons of an antitumour strategy. Br J Pharmacol (2006) 1.18
Antineoplastic activity of cannabinoids. J Natl Cancer Inst (1975) 1.14
A novel classification of lung cancer into molecular subtypes. PLoS One (2012) 1.13
Pathogenesis of lung cancer signalling pathways: roadmap for therapies. Eur Respir J (2009) 1.10
The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis. Cell Death Differ (2003) 1.09
Targeting the endocannabinoid system in cancer therapy: a call for further research. Nat Med (2002) 1.09
Expression and function of fatty acid amide hydrolase in prostate cancer. Int J Cancer (2008) 1.09
Cannabinoids, endocannabinoids, and cancer. Cancer Metastasis Rev (2011) 1.09
FAAH and anandamide: is 2-AG really the odd one out? Trends Pharmacol Sci (2008) 1.04
Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis. Cancer Prev Res (Phila) (2010) 1.03
Delta9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Oncogene (2007) 1.03
Cannabinoids in the treatment of cancer. Cancer Lett (2009) 1.03
Personalized treatment of lung cancer. Semin Oncol (2011) 1.01
The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway. Exp Cell Res (2006) 0.98
Influence of angiogenetic factors and matrix metalloproteinases upon tumour progression in non-small-cell lung cancer. Br J Cancer (2001) 0.92
Tumor-suppressive effects of psoriasin (S100A7) are mediated through the β-catenin/T cell factor 4 protein pathway in estrogen receptor-positive breast cancer cells. J Biol Chem (2011) 0.92
Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth. FASEB J (2001) 0.91
Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents. Best Pract Res Clin Endocrinol Metab (2009) 0.90
A physiological role for endocannabinoid-derived products of cyclooxygenase-2-mediated oxidative metabolism. Br J Pharmacol (2008) 0.88
Inactivation and biotransformation of the endogenous cannabinoids anandamide and 2-arachidonoylglycerol. Mol Pharmacol (2009) 0.86
High levels of γ-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer. BMC Cancer (2013) 0.86
NF-kappaB in lung tumorigenesis. Cancers (Basel) (2011) 0.80
Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis. Cancer Res (2008) 3.16
MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J Biol Chem (2009) 3.16
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Mol Cell Biol (2007) 2.07
Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells. J Biol Chem (2003) 1.73
Primary pulmonary and mediastinal synovial sarcoma: a clinicopathologic study of 60 cases and comparison with five prior series. Mod Pathol (2007) 1.61
Signal transducer and activator of transcription factor 1 mediates apoptosis induced by hepatitis C virus and HIV envelope proteins in hepatocytes. J Infect Dis (2006) 1.60
Overexpression of phospho-eIF4E is associated with survival through AKT pathway in non-small cell lung cancer. Clin Cancer Res (2009) 1.41
Slit-2/Robo-1 modulates the CXCL12/CXCR4-induced chemotaxis of T cells. J Leukoc Biol (2007) 1.39
Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells. J Biol Chem (2008) 1.38
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer. Mol Cancer Ther (2009) 1.36
Hepatitis C and human immunodeficiency virus envelope proteins cooperatively induce hepatocytic apoptosis via an innocent bystander mechanism. J Infect Dis (2003) 1.33
Medicinal plants and cancer chemoprevention. Curr Drug Metab (2008) 1.27
Cannabinoid receptor CB2 modulates the CXCL12/CXCR4-mediated chemotaxis of T lymphocytes. Mol Immunol (2006) 1.26
S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways. Cancer Res (2011) 1.25
Hepatitis C virus and HIV envelope proteins collaboratively mediate interleukin-8 secretion through activation of p38 MAP kinase and SHP2 in hepatocytes. J Biol Chem (2003) 1.13
Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition. J Cell Biochem (2011) 1.12
Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45. J Biol Chem (2003) 1.11
SMAD6 contributes to patient survival in non-small cell lung cancer and its knockdown reestablishes TGF-beta homeostasis in lung cancer cells. Cancer Res (2008) 1.09
Congenital hypomyelinating neuropathy, central dysmyelination, and Waardenburg-Hirschsprung disease: phenotypes linked by SOX10 mutation. Ann Neurol (2002) 1.06
Lipopolysaccharide-induced apoptosis of endothelial cells and its inhibition by vascular endothelial growth factor. J Immunol (2002) 1.05
Depletion of beta-arrestin-2 promotes tumor growth and angiogenesis in a murine model of lung cancer. J Immunol (2008) 1.05
Cannabinoid receptors, CB1 and CB2, as novel targets for inhibition of non-small cell lung cancer growth and metastasis. Cancer Prev Res (Phila) (2010) 1.03
Cbl and Akt regulate CXCL8-induced and CXCR1- and CXCR2-mediated chemotaxis. Int Immunol (2006) 1.03
Phytoestrogens and breast cancer prevention: possible mechanisms of action. Environ Health Perspect (2008) 1.02
Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2. Hepatology (2013) 0.99
The tyrosine kinase Pyk2 mediates lipopolysaccharide-induced IL-8 expression in human endothelial cells. J Immunol (2008) 0.98
Granulomatous reaction to pneumocystis jirovecii: clinicopathologic review of 20 cases. Am J Surg Pathol (2010) 0.97
S100A7-downregulation inhibits epidermal growth factor-induced signaling in breast cancer cells and blocks osteoclast formation. PLoS One (2008) 0.97
Crosstalk between chemokine receptor CXCR4 and cannabinoid receptor CB2 in modulating breast cancer growth and invasion. PLoS One (2011) 0.97
Molecular mechanism of hepatic injury in coinfection with hepatitis C virus and HIV. Clin Infect Dis (2005) 0.97
Cdc25A regulates matrix metalloprotease 1 through Foxo1 and mediates metastasis of breast cancer cells. Mol Cell Biol (2011) 0.96
HIV-1 gp120-induced migration of dendritic cells is regulated by a novel kinase cascade involving Pyk2, p38 MAP kinase, and LSP1. Blood (2009) 0.96
Molecular characterization of tlyA gene product, Rv1694 of Mycobacterium tuberculosis: a non-conventional hemolysin and a ribosomal RNA methyl transferase. BMC Biochem (2010) 0.96
Occult primary parotid gland acinic cell adenocarcinoma presenting with extensive lung metastasis. Arch Pathol Lab Med (2007) 0.95
CXCR4/CCR5 down-modulation and chemotaxis are regulated by the proteasome pathway. J Biol Chem (2002) 0.94
Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia. J Immunol (2013) 0.94
Tumor genetics and survival of thymic neuroendocrine neoplasms: a multi-institutional clinicopathologic study. Genes Chromosomes Cancer (2014) 0.93
Desmoglein 3 as a prognostic factor in lung cancer. Hum Pathol (2006) 0.93
Histological spectrum of pulmonary manifestations in kidney transplant recipients on sirolimus inclusive immunosuppressive regimens. Diagn Pathol (2012) 0.93
Glucose transporter-1 in pulmonary neuroendocrine carcinomas: expression and survival analysis. Mod Pathol (2009) 0.92
Tumor-suppressive effects of psoriasin (S100A7) are mediated through the β-catenin/T cell factor 4 protein pathway in estrogen receptor-positive breast cancer cells. J Biol Chem (2011) 0.92
LPS-induced MCP-1 expression in human microvascular endothelial cells is mediated by the tyrosine kinase, Pyk2 via the p38 MAPK/NF-kappaB-dependent pathway. Mol Immunol (2008) 0.91
Somatic Mutation Spectrum of Non-Small-Cell Lung Cancer in African Americans: A Pooled Analysis. J Thorac Oncol (2015) 0.90
Activation and regulation of platelet-activating factor receptor: role of G(i) and G(q) in receptor-mediated chemotactic, cytotoxic, and cross-regulatory signals. J Immunol (2006) 0.90
C-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment. Breast Cancer Res (2014) 0.90
Altered p16(INK4) and RB1 Expressions Are Associated with Poor Prognosis in Patients with Nonsmall Cell Lung Cancer. J Oncol (2012) 0.90
N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton. Retrovirology (2013) 0.89
Mutant HSPB1 overexpression in neurons is sufficient to cause age-related motor neuronopathy in mice. Neurobiol Dis (2012) 0.88
CXCR3 deficiency enhances tumor progression by promoting macrophage M2 polarization in a murine breast cancer model. Immunology (2014) 0.88
Structural proteins of Hepatitis C virus induce interleukin 8 production and apoptosis in human endothelial cells. J Gen Virol (2005) 0.86
Differential role of psoriasin (S100A7) in estrogen receptor α positive and negative breast cancer cells occur through actin remodeling. Breast Cancer Res Treat (2013) 0.85
mRNA cap methylation influences pathogenesis of vesicular stomatitis virus in vivo. J Virol (2013) 0.85
HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45. J Biol Chem (2006) 0.84
Impaired regeneration in LGMD2A supported by increased PAX7-positive satellite cell content and muscle-specific microrna dysregulation. Muscle Nerve (2013) 0.82
Activation of the connective tissue growth factor (CTGF)-transforming growth factor β 1 (TGF-β 1) axis in hepatitis C virus-expressing hepatocytes. PLoS One (2012) 0.82
Membrane bound monomer of Staphylococcal alpha-hemolysin induces caspase activation and apoptotic cell death despite initiation of membrane repair pathway. PLoS One (2009) 0.81
The use of genetic markers to identify lung cancer in fine needle aspiration samples. Clin Cancer Res (2008) 0.81
Expression Analysis of p16, c-Myc, and mSin3A in Non-small Cell Lung Cancer by Computer Aided Scoring and Analysis (CASA). Clin Lab (2015) 0.80
Detection of silicone in lung tissue. Arch Pathol Lab Med (2012) 0.78
Underlying pathophysiology of HCV infection in HIV-positive drug users. J Addict Dis (2008) 0.78
Alveolar airspace and pulmonary artery involvement by extramedullary hematopoiesis: a unique manifestation of myelofibrosis. Arch Pathol Lab Med (2008) 0.78
The adaptor protein SLP-76 regulates HIV-1 release and cell-to-cell transmission in T cells. J Immunol (2012) 0.78
A novel role for Slit2/Robo1 axis in modulating HIV-1 replication in T cells. AIDS (2011) 0.77
Anaplastic papillary glioneuronal tumor with extraneural metastases. J Neuropathol Exp Neurol (2014) 0.77
Congenital pulmonary airway malformation presenting as unilateral cystic lung disease. Am J Respir Crit Care Med (2013) 0.77
CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis. J Clin Invest (2014) 0.76
Deposition of calcium salts in a case of pulmonary zygomycosis: histopathologic and chemical findings. Hum Pathol (2009) 0.76
Taxol and 10-deacetylbaccatinIII induce distinct changes in the dynamics of caveolae. FEBS Lett (2008) 0.76
Pathogenesis of autosomal dominant hereditary spastic paraplegia (SPG6) revealed by a rat model. J Neuropathol Exp Neurol (2013) 0.75
Alpha-chemokine-mediated signal transduction in human Kaposi's sarcoma spindle cells. Biochim Biophys Acta (2004) 0.75
Modulation of PP2A activity by Jacalin: is it through caveolae and ER chaperones? Glycoconj J (2009) 0.75
Absence of human herpesvirus-8 in pulmonary inflammatory myofibroblastic tumor: immunohistochemical and molecular analysis of 20 cases. Mod Pathol (2007) 0.75
Diagnostic value of blood clot core during endobronchial ultrasound-guided transbronchial needle aspirate. Lung (2013) 0.75
Crospovidone and Microcrystalline Cellulose: A Novel Description of Pharmaceutical Fillers in the Gastrointestinal Tract. Am J Surg Pathol (2017) 0.75