|
1
|
Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.
|
J Med Chem
|
2014
|
0.93
|
|
2
|
Optimization of pyrrolamides as mycobacterial GyrB ATPase inhibitors: structure-activity relationship and in vivo efficacy in a mouse model of tuberculosis.
|
Antimicrob Agents Chemother
|
2013
|
0.87
|
|
3
|
4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.
|
J Med Chem
|
2014
|
0.82
|
|
4
|
N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds.
|
J Med Chem
|
2014
|
0.82
|
|
5
|
Pyrazolopyrimidines establish MurC as a vulnerable target in Pseudomonas aeruginosa and Escherichia coli.
|
ACS Chem Biol
|
2014
|
0.77
|