PubRank

Vasan K Sambandamurthy

Author PubWeight™ 19.38‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Survival perspectives from the world's most successful pathogen, Mycobacterium tuberculosis. Nat Immunol 2003 2.03
2 Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates. Vaccine 2009 1.38
3 Protection elicited by a double leucine and pantothenate auxotroph of Mycobacterium tuberculosis in guinea pigs. Infect Immun 2004 1.34
4 Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis. J Antimicrob Chemother 2008 1.28
5 Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo. J Med Chem 2013 0.97
6 Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis. J Med Chem 2014 0.93
7 Characterization of the protective T-cell response generated in CD4-deficient mice by a live attenuated Mycobacterium tuberculosis vaccine. Immunology 2006 0.92
8 Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis. ACS Chem Biol 2012 0.90
9 Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity. J Med Chem 2014 0.89
10 Methyl-thiazoles: a novel mode of inhibition with the potential to develop novel inhibitors targeting InhA in Mycobacterium tuberculosis. J Med Chem 2013 0.88
11 Optimization of pyrrolamides as mycobacterial GyrB ATPase inhibitors: structure-activity relationship and in vivo efficacy in a mouse model of tuberculosis. Antimicrob Agents Chemother 2013 0.87
12 Aminoazabenzimidazoles, a novel class of orally active antimalarial agents. J Med Chem 2014 0.83
13 N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds. J Med Chem 2014 0.82
14 4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity. J Med Chem 2014 0.82
15 Lead optimization of 1,4-azaindoles as antimycobacterial agents. J Med Chem 2014 0.82
16 Exploring the mode of action of bioactive compounds by microfluidic transcriptional profiling in mycobacteria. PLoS One 2013 0.80
17 Synthesis and structure activity relationship of imidazo[1,2-a]pyridine-8-carboxamides as a novel antimycobacterial lead series. Bioorg Med Chem Lett 2013 0.79
18 Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B. J Med Chem 2013 0.78
19 Pyrazolopyrimidines establish MurC as a vulnerable target in Pseudomonas aeruginosa and Escherichia coli. ACS Chem Biol 2014 0.77
20 Induction of high levels of protective immunity in mice after vaccination using dendritic cells infected with auxotrophic mutants of Mycobacterium tuberculosis. Immunol Lett 2005 0.76