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1
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Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis.
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Science
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2009
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3.39
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2
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Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis.
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Sci Transl Med
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2012
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1.78
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3
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MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212.
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Antimicrob Agents Chemother
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2011
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1.51
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4
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Mycobacterium tuberculosis: drug resistance and future perspectives.
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Future Microbiol
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2009
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1.29
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5
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Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome.
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BMC Microbiol
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2006
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1.26
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6
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Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system.
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Tuberculosis (Edinb)
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2008
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1.24
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7
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Deciphering the role of RND efflux transporters in Burkholderia cenocepacia.
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PLoS One
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2011
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1.14
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8
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Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance.
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Mol Microbiol
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2010
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1.12
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9
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The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis.
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Appl Microbiol Biotechnol
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2013
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1.04
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10
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Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection.
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PLoS One
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2013
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0.94
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11
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Characterization and heterologous expression of the oxalyl coenzyme A decarboxylase gene from Bifidobacterium lactis.
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Appl Environ Microbiol
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2004
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0.93
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12
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LfrR is a repressor that regulates expression of the efflux pump LfrA in Mycobacterium smegmatis.
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Antimicrob Agents Chemother
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2006
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0.88
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13
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Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis.
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PLoS One
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2011
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0.86
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14
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Exploring the HME and HAE1 efflux systems in the genus Burkholderia.
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BMC Evol Biol
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2010
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0.85
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15
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Phenotypic and genotypic characterisation of Burkholderia cenocepacia J2315 mutants affected in homoserine lactone and diffusible signal factor-based quorum sensing systems suggests interplay between both types of systems.
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PLoS One
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2013
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0.85
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16
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Rv2466c mediates the activation of TP053 to kill replicating and non-replicating Mycobacterium tuberculosis.
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ACS Chem Biol
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2014
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0.83
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17
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Genomic analysis of zinc homeostasis in Mycobacterium tuberculosis.
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FEMS Microbiol Lett
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2008
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0.83
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18
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Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis.
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Eur J Med Chem
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2013
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0.83
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19
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A census of RND superfamily proteins in the Burkholderia genus.
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Future Microbiol
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2013
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0.82
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20
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4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.
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J Med Chem
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2014
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0.82
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21
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Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain.
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Res Microbiol
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2005
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0.81
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22
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Retracted
Antituberculars which target decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1: state of art.
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Appl Microbiol Biotechnol
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2012
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0.79
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23
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Control of MRSA infection and colonisation in an intensive care unit by GeneOhm MRSA assay and culture methods.
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BMC Infect Dis
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2009
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0.79
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24
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Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents.
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Eur J Med Chem
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2012
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0.78
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25
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Synthesis and evaluation of α-ketotriazoles and α,β-diketotriazoles as inhibitors of Mycobacterium tuberculosis.
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Eur J Med Chem
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2013
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0.77
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26
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Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents.
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Eur J Med Chem
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2011
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0.77
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27
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DprE1, a new taxonomic marker in mycobacteria.
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FEMS Microbiol Lett
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2013
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0.76
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28
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Iron Acquisition Pathways as Targets for Antitubercular Drugs.
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Curr Med Chem
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2016
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0.75
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29
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A phenotypic based target screening approach delivers new antitubercular CTP synthetase inhibitors.
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ACS Infect Dis
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2017
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0.75
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