João Neres

Author PubWeight™ 11.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med 2012 1.36
2 Towards a new combination therapy for tuberculosis with next generation benzothiazinones. EMBO Mol Med 2014 1.27
3 Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5'-O-[N-(salicyl)sulfamoyl]adenosine: antibacterial nucleosides effective against Mycobacterium tuberculosis. J Med Chem 2008 1.21
4 Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance. Mol Microbiol 2010 1.12
5 Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis. Biochemistry 2010 1.04
6 Synthesis, stability and in vitro dermal evaluation of aminocarbonyloxymethyl esters as prodrugs of carboxylic acid agents. Bioorg Med Chem 2002 1.02
7 Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes. Biochemistry 2010 0.92
8 Inhibitors of the salicylate synthase (MbtI) from Mycobacterium tuberculosis discovered by high-throughput screening. ChemMedChem 2010 0.89
9 Tryptophan as a molecular shovel in the glycosyl transfer activity of Trypanosoma cruzi trans-sialidase. Biophys J 2010 0.82
10 The global virulence regulators VsrAD and PhcA control secondary metabolism in the plant pathogen Ralstonia solanacearum. Chembiochem 2009 0.82
11 4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity. J Med Chem 2014 0.82
12 Insights into the activity and specificity of Trypanosoma cruzi trans-sialidase from molecular dynamics simulations. Biochemistry 2013 0.78
13 Design, synthesis, and enzymatic evaluation of N1-acyloxyalkyl- and N1-oxazolidin-2,4-dion-5-yl-substituted beta-lactams as novel inhibitors of human leukocyte elastase. J Med Chem 2005 0.75