Published in Int J Nanomedicine on May 15, 2014
Cerium oxide nanoparticles attenuate acute kidney injury induced by intra-abdominal infection in Sprague-Dawley rats. J Nanobiotechnology (2015) 0.76
ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration. Oxid Med Cell Longev (2017) 0.75
Autophagy Is a Protective Response to the Oxidative Damage to Endplate Chondrocytes in Intervertebral Disc: Implications for the Treatment of Degenerative Lumbar Disc. Oxid Med Cell Longev (2017) 0.75
Poly(γ-glutamic acid) and poly(γ-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc. J Mater Sci Mater Med (2016) 0.75
Nanoparticle fullerol alleviates radiculopathy via NLRP3 inflammasome and neuropeptides. Nanomedicine (2017) 0.75
Icariin Prevents H2O2-Induced Apoptosis via the PI3K/Akt Pathway in Rat Nucleus Pulposus Intervertebral Disc Cells. Evid Based Complement Alternat Med (2017) 0.75
Reactive oxygen species: metabolism, oxidative stress, and signal transduction. Annu Rev Plant Biol (2004) 18.76
Mechanical initiation of intervertebral disc degeneration. Spine (Phila Pa 1976) (2000) 2.76
A slowly progressive and reproducible animal model of intervertebral disc degeneration characterized by MRI, X-ray, and histology. Spine (Phila Pa 1976) (2005) 2.14
2001 Volvo Award Winner in Basic Science Studies: Effect of nutrient supply on the viability of cells from the nucleus pulposus of the intervertebral disc. Spine (Phila Pa 1976) (2001) 2.08
Degeneration and the chemical composition of the human lumbar intervertebral disc. J Orthop Res (1987) 1.80
1997 Volvo Award winner in basic science studies. Immunohistologic markers for age-related changes of human lumbar intervertebral discs. Spine (Phila Pa 1976) (1997) 1.75
Quantitative analysis of gene expression in a rabbit model of intervertebral disc degeneration by real-time polymerase chain reaction. Spine J (2005) 1.74
Osteogenic protein-1 injection into a degenerated disc induces the restoration of disc height and structural changes in the rabbit anular puncture model. Spine (Phila Pa 1976) (2006) 1.74
Fullerene derivatives protect against oxidative stress in RAW 264.7 cells and ischemia-reperfused lungs. Am J Physiol Regul Integr Comp Physiol (2004) 1.63
Effects of growth differentiation factor-5 on the intervertebral disc--in vitro bovine study and in vivo rabbit disc degeneration model study. Spine (Phila Pa 1976) (2006) 1.62
Effect of nutrient deprivation on the viability of intervertebral disc cells. Eur Spine J (2004) 1.60
The course of macroscopic degeneration in the human lumbar intervertebral disc. Spine (Phila Pa 1976) (2006) 1.46
Feasibility of a stem cell therapy for intervertebral disc degeneration. Spine J (2007) 1.44
Anti-apoptotic effects of IGF-1 and PDGF on human intervertebral disc cells in vitro. Spine (Phila Pa 1976) (2000) 1.43
Mechanical stress-induced apoptosis of endplate chondrocytes in organ-cultured mouse intervertebral discs: an ex vivo study. Spine (Phila Pa 1976) (2003) 1.32
Prevention of disc degeneration with growth factors. Eur Spine J (2006) 1.29
Biological treatment strategies for disc degeneration: potentials and shortcomings. Eur Spine J (2006) 1.25
Biologic response of the intervertebral disc to static and dynamic compression in vitro. Spine (Phila Pa 1976) (2007) 1.21
Molecular biology of degenerative disc disease. Neurosurgery (2000) 1.20
In vitro antioxidant activity of liquor from fermented shrimp biowaste. Bioresour Technol (2008) 1.14
Degeneration of intervertebral discs: current understanding of cellular and molecular events, and implications for novel therapies. Expert Rev Mol Med (2001) 1.12
The apoptotic effects of oxidative stress and antiapoptotic effects of caspase inhibitors on rat notochordal cells. Spine (Phila Pa 1976) (2007) 1.10
p38 MAPK inhibition modulates rabbit nucleus pulposus cell response to IL-1. J Orthop Res (2008) 1.09
Protective effects of fullerenol C60(OH)24 against doxorubicin-induced cardiotoxicity and hepatotoxicity in rats with colorectal cancer. Biomaterials (2008) 1.09
p38 MAPK inhibition in nucleus pulposus cells: a potential target for treating intervertebral disc degeneration. Spine (Phila Pa 1976) (2007) 1.07
Water-soluble C60 fullerene prevents degeneration of articular cartilage in osteoarthritis via down-regulation of chondrocyte catabolic activity and inhibition of cartilage degeneration during disease development. Arthritis Rheum (2007) 1.06
Modulating activity of fullerol C60(OH)22 on doxorubicin-induced cytotoxicity. Toxicol In Vitro (2004) 1.05
Characterization of in vivo effects of platelet-rich plasma and biodegradable gelatin hydrogel microspheres on degenerated intervertebral discs. Tissue Eng Part A (2009) 1.02
Polyhydroxylated C60, fullerenol, a novel free-radical trapper, prevented hydrogen peroxide- and cumene hydroperoxide-elicited changes in rat hippocampus in-vitro. J Pharm Pharmacol (1997) 1.02
Balancing the generation and elimination of reactive oxygen species. Proc Natl Acad Sci U S A (2005) 1.01
In vivo dynamic stiffness of the porcine lumbar spine exposed to cyclic loading: influence of load and degeneration. J Spinal Disord (1998) 1.01
Is interleukin-1 a good target for therapeutic intervention in intervertebral disc degeneration: lessons from the osteoarthritic experience. Arthritis Res Ther (2007) 1.01
Polyhydroxylated fullerene derivative C(60)(OH)(24) prevents mitochondrial dysfunction and oxidative damage in an MPP(+) -induced cellular model of Parkinson's disease. J Neurosci Res (2008) 1.01
Aggrecan turnover in human intervertebral disc as determined by the racemization of aspartic acid. J Biol Chem (2006) 0.99
Phototoxicity and cytotoxicity of fullerol in human lens epithelial cells. Toxicol Appl Pharmacol (2007) 0.98
Fullerenes for applications in biology and medicine. Curr Med Chem (2011) 0.98
Anti-apoptotic effects of caspase inhibitors on rat intervertebral disc cells. J Bone Joint Surg Am (2006) 0.98
Unloaded movement facilitation exercise compared to no exercise or alternative therapy on outcomes for people with nonspecific chronic low back pain: a systematic review. J Manipulative Physiol Ther (2007) 0.98
Nitric oxide mediates the change of proteoglycan synthesis in the human lumbar intervertebral disc in response to hydrostatic pressure. Spine (Phila Pa 1976) (2001) 0.98
Cyclic tensile stretch modulates proteoglycan production by intervertebral disc annulus fibrosus cells through production of nitrite oxide. J Cell Biochem (2003) 0.97
An autocrine or paracrine Fas-mediated counterattack: a potential mechanism for apoptosis of notochordal cells in intact rat nucleus pulposus. Spine (Phila Pa 1976) (2005) 0.97
Histochemical and ultrastructural observations on brown degeneration of human intervertebral disc. J Orthop Res (1991) 0.96
Intervertebral disc cell apoptosis by nitric oxide: biological understanding of intervertebral disc degeneration. Kobe J Med Sci (2000) 0.96
Herniation of cervical intervertebral disc: immunohistochemical examination and measurement of nitric oxide production. Spine (Phila Pa 1976) (2001) 0.96
Antioxidant effects of water-soluble fullerene derivatives against ultraviolet ray or peroxylipid through their action of scavenging the reactive oxygen species in human skin keratinocytes. Biomed Pharmacother (2005) 0.95
Nitric oxide-scavenging activity of polyhydroxylated fullerenol, C60(OH)24. Nitric Oxide (2004) 0.94
Potential hepatoprotective effects of fullerenol C60(OH)24 in doxorubicin-induced hepatotoxicity in rats with mammary carcinomas. Biomaterials (2008) 0.93
In vitro toxicity assessment of three hydroxylated fullerenes in human skin cells. Toxicol In Vitro (2011) 0.93
The in vivo biological effects of intradiscal recombinant human bone morphogenetic protein-2 on the injured intervertebral disc: an animal experiment. Spine (Phila Pa 1976) (2007) 0.92
Biological treatment for degenerative disc disease: implications for the field of physical medicine and rehabilitation. Am J Phys Med Rehabil (2008) 0.92
Immunomorphological analysis of RAGE receptor expression and NF-kappaB activation in tissue samples from normal and degenerated intervertebral discs of various ages. Ann N Y Acad Sci (2007) 0.92
Effect of oxygen levels on proteoglycan synthesis by intervertebral disc cells. Spine (Phila Pa 1976) (2011) 0.91
Collagen in the ageing human intervertebral disc: an increase in covalently bound fluorophores and chromophores. Biochim Biophys Acta (1991) 0.90
Cellular uptake and cytotoxic evaluation of fullerenol in different cell lines. Toxicology (2009) 0.90
IGF-1 rescues human intervertebral annulus cells from in vitro stress-induced premature senescence. Growth Factors (2008) 0.89
Fullerene derivatives protect endothelial cells against NO-induced damage. Nanotechnology (2009) 0.86
Fullerol cluster formation in aqueous solutions: implications for environmental release. J Colloid Interface Sci (2007) 0.86
Antioxidant properties of fullerenol C60(OH)24 in rat kidneys, testes, and lungs treated with doxorubicin. Toxicol Mech Methods (2010) 0.86
FoxOs: Unifying links between oxidative stress and skeletal homeostasis. Curr Osteoporos Rep (2011) 0.86
Fullerenol C60(OH)24 prevents doxorubicin-induced acute cardiotoxicity in rats. Pharmacol Rep (2010) 0.85
Physiology and pathophysiology of nitrosative and oxidative stress in osteoarthritic joint destruction. Can J Physiol Pharmacol (2011) 0.85
Biologic treatment for intervertebral disc degeneration: summary statement. Spine (Phila Pa 1976) (2003) 0.84
Free radical scavenging activity of fullerenol on grafts after small bowel transplantation in dogs. Transplant Proc (2000) 0.84
The use of fullerene substituted phenylalanine amino acid as a passport for peptides through cell membranes. Org Biomol Chem (2006) 0.83
Enhancement of matrix production and cell proliferation in human annulus cells under bioreactor culture. Tissue Eng Part A (2011) 0.83
Fullerol antagonizes dexamethasone-induced oxidative stress and adipogenesis while enhancing osteogenesis in a cloned bone marrow mesenchymal stem cell. J Orthop Res (2012) 0.83
Novel polyhydroxylated fullerene suppresses intracellular oxidative stress together with repression of intracellular lipid accumulation during the differentiation of OP9 preadipocytes into adipocytes. Free Radic Res (2010) 0.82
Concentration-dependent effects of fullerenol on cultured hippocampal neuron viability. Int J Nanomedicine (2012) 0.81
Heme oxygenase-1 induction by (S)-enantiomer of YS-51 (YS-51S), a synthetic isoquinoline alkaloid, inhibits nitric oxide production and nuclear factor-kappaB translocation in ROS 17/2.8 cells activated with inflammatory stimulants. Int Immunopharmacol (2007) 0.80
Effect of fullerenol C(60)(OH) (24) on lipid peroxidation of kidneys, testes and lungs in rats treated with doxorubicine. Eur J Drug Metab Pharmacokinet (2012) 0.80
Animal models of disc degeneration and major genetic strategies. Pain Physician (2013) 0.78
Cardioprotective effects of fullerenol C(60)(Oh)(24) on a single dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Technol Cancer Res Treat (2008) 0.78
Construction of anticoagulant poly (lactic acid) films via surface covalent graft of heparin-carrying microcapsules. Colloids Surf B Biointerfaces (2008) 0.77
Polyhydroxylated fullerene C₆₀(OH)₄₄ suppresses intracellular lipid accumulation together with repression of intracellular superoxide anion radicals and subsequent PPARγ2 expression during spontaneous differentiation of OP9 preadipocytes into adipocytes. Mol Cell Biochem (2012) 0.76
Transcriptional alteration of matrix-related gene expression in cultured human disc cells by nanoparticles of a bismethanophosphonate fullerene. Cell Biol Int (2010) 0.75