A community effort to assess and improve drug sensitivity prediction algorithms.

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🔗 View Article (PMC 4547623)

Published in Nat Biotechnol on June 01, 2014

Authors

James C Costello1, Laura M Heiser2, Elisabeth Georgii3, Mehmet Gönen4, Michael P Menden5, Nicholas J Wang6, Mukesh Bansal7, Muhammad Ammad-ud-din4, Petteri Hintsanen8, Suleiman A Khan4, John-Patrick Mpindi8, Olli Kallioniemi8, Antti Honkela9, Tero Aittokallio8, Krister Wennerberg8, NCI DREAM Community, James J Collins10, Dan Gallahan11, Dinah Singer11, Julio Saez-Rodriguez5, Samuel Kaski12, Joe W Gray6, Gustavo Stolovitzky13

Author Affiliations

1: 1] Howard Hughes Medical Institute, Boston University, Boston, Massachusetts, USA. [2] Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA. [3] [4].
2: 1] Department of Biomedical Engineering, Oregon Health and Science University, Portland, Oregon, USA. [2].
3: 1] Helsinki Institute for Information Technology HIIT, Department of Information and Computer Science, Aalto University, Espoo, Finland. [2].
4: Helsinki Institute for Information Technology HIIT, Department of Information and Computer Science, Aalto University, Espoo, Finland.
5: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK.
6: Department of Biomedical Engineering, Oregon Health and Science University, Portland, Oregon, USA.
7: Department of Systems Biology, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, USA.
8: Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland.
9: Helsinki Institute for Information Technology HIIT, Department of Computer Science, University of Helsinki, Helsinki, Finland.
10: 1] Howard Hughes Medical Institute, Boston University, Boston, Massachusetts, USA. [2] Department of Biomedical Engineering, Boston University, Boston, Massachusetts, USA. [3] Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, USA.
11: National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
12: 1] Helsinki Institute for Information Technology HIIT, Department of Information and Computer Science, Aalto University, Espoo, Finland. [2] Helsinki Institute for Information Technology HIIT, Department of Computer Science, University of Helsinki, Helsinki, Finland.
13: IBM T.J. Watson Research Center, IBM, Yorktown Heights, New York, USA.

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