Published in Trials on May 30, 2014
Acupuncture for Relieving Perimenopausal Symptoms | NCT01933204
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Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA (2002) 80.37
Breast cancer and hormone-replacement therapy in the Million Women Study. Lancet (2003) 18.24
Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med (2003) 10.06
NIH Consensus Conference. Acupuncture. JAMA (1998) 6.53
Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized trial. JAMA (2003) 5.26
Endometrial cancer and hormone-replacement therapy in the Million Women Study. Lancet (2005) 5.20
The 2012 hormone therapy position statement of: The North American Menopause Society. Menopause (2012) 4.04
The placebo needle, is it a valid and convincing placebo for use in acupuncture trials? A randomised, single-blind, cross-over pilot trial. Pain (2003) 3.96
Change in health-related quality of life over the menopausal transition in a multiethnic cohort of middle-aged women: Study of Women's Health Across the Nation. Menopause (2009) 2.36
Oral oestrogen and combined oestrogen/progestogen therapy versus placebo for hot flushes. Cochrane Database Syst Rev (2004) 2.03
Menopausal symptoms and treatment-related effects of estrogen and progestin in the Women's Health Initiative. Obstet Gynecol (2005) 2.01
The Menopause Rating Scale (MRS): reliability of scores of menopausal complaints. Climacteric (2000) 1.91
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Acupuncture for hot flashes: a randomized, sham-controlled clinical study. Menopause (2007) 1.78
Use of alternative therapies for menopause symptoms: results of a population-based survey. Obstet Gynecol (2002) 1.75
International versions of the Menopause Rating Scale (MRS). Health Qual Life Outcomes (2003) 1.70
Effects of acupuncture on hot flashes in perimenopausal and postmenopausal women--a multicenter randomized clinical trial. Menopause (2010) 1.63
The Menopause Rating Scale (MRS): comparison with Kupperman index and quality-of-life scale SF-36. Climacteric (2000) 1.62
A randomized, controlled pilot study of acupuncture treatment for menopausal hot flashes. Menopause (2008) 1.60
Survey of adverse events following acupuncture (SAFA): a prospective study of 32,000 consultations. Acupunct Med (2001) 1.55
Pilot evaluation of black cohosh for the treatment of hot flashes in women. Cancer Invest (2004) 1.55
Updated IMS recommendations on postmenopausal hormone therapy and preventive strategies for midlife health. Climacteric (2011) 1.47
[The Menopause Rating Scale (MRS II): methodological standardization in the German population]. Zentralbl Gynakol (2000) 1.46
The menopausal transition was associated in a prospective study with decreased health functioning in women who report menopausal symptoms. J Clin Epidemiol (2005) 1.44
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A universal menopausal syndrome? Am J Med (2005) 1.24
Prospective evaluation of body weight and body fat distribution in early postmenopausal women with and without hormonal replacement therapy. Maturitas (2001) 1.22
Placebo and the new physiology of the doctor-patient relationship. Physiol Rev (2013) 1.20
Incidence of adverse effects during acupuncture therapy-a multicentre survey. Complement Ther Med (2003) 1.08
Type of menopause, patterns of hormone therapy use, and hot flashes. Fertil Steril (2006) 1.04
Acupuncture for hot flushes in perimenopausal and postmenopausal women: a randomised, sham-controlled trial. Acupunct Med (2011) 0.92
The role of complementary and alternative medicine in management of menopausal symptoms. Endocrinol Metab Clin North Am (2004) 0.92
A pilot randomized, single-blind, placebo-controlled trial of traditional acupuncture for vasomotor symptoms and mechanistic pathways of menopause. Menopause (2012) 0.90
Prevalence and clustering of menopausal symptoms in older women by hysterectomy and oophorectomy status. J Womens Health Gend Based Med (2000) 0.88
Cyproterone acetate, an alternative gestagen in postmenopausal oestrogen/gestagen therapy. Clin Endocrinol (Oxf) (1987) 0.83
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The role of calcium in peri- and postmenopausal women: consensus opinion of The North American Menopause Society. Menopause (2001) 0.79
[Distribution characteristics of common syndrome types and syndrome elements extracted by experts' experience in perimenopausal and postmenopausal women]. Zhong Xi Yi Jie He Xue Bao (2009) 0.77
Endometrial effects during hormone replacement therapy with a sequential oestradiol valerate/cyproterone acetate preparation. Maturitas (1993) 0.76
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Translating the A1C assay into estimated average glucose values. Diabetes Care (2008) 11.55
The US National Comorbidity Survey Replication (NCS-R): design and field procedures. Int J Methods Psychiatr Res (2004) 10.47
A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures. Nat Genet (2008) 8.44
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Modified glomerular filtration rate estimating equation for Chinese patients with chronic kidney disease. J Am Soc Nephrol (2006) 8.05
Genome sequence and analysis of the tuber crop potato. Nature (2011) 7.77
Allele-specific copy number analysis of tumors. Proc Natl Acad Sci U S A (2010) 7.70
Rapid health transition in China, 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet (2013) 7.70
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity (2008) 7.60
Epidemiology of human infections with avian influenza A(H7N9) virus in China. N Engl J Med (2013) 7.52
Evolution of China's response to HIV/AIDS. Lancet (2007) 7.34
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med (2006) 6.86
Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination. Vaccine (2009) 6.30
National survey of drug-resistant tuberculosis in China. N Engl J Med (2012) 6.28
Negative Staining and Image Classification - Powerful Tools in Modern Electron Microscopy. Biol Proced Online (2004) 6.14
Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. Lancet (2013) 6.10
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Fate mapping of IL-17-producing T cells in inflammatory responses. Nat Immunol (2011) 5.98
Emergence and control of infectious diseases in China. Lancet (2008) 5.93
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell (2011) 5.91
Incorporating structure to predict microRNA targets. Proc Natl Acad Sci U S A (2005) 5.68
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration. Science (2006) 5.67
DNA helicase Srs2 disrupts the Rad51 presynaptic filament. Nature (2003) 5.66
Natural variation in Ghd7 is an important regulator of heading date and yield potential in rice. Nat Genet (2008) 5.64
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nat Genet (2011) 5.62
Validation of the ITS2 region as a novel DNA barcode for identifying medicinal plant species. PLoS One (2010) 5.39
Aptamers evolved from live cells as effective molecular probes for cancer study. Proc Natl Acad Sci U S A (2006) 5.35
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest (2003) 5.32
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell (2005) 5.10
Nosocomial transmission of human granulocytic anaplasmosis in China. JAMA (2008) 5.01
Mitochondrial gene replacement in primate offspring and embryonic stem cells. Nature (2009) 4.98
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc Natl Acad Sci U S A (2010) 4.95
Glucose levels and risk of dementia. N Engl J Med (2013) 4.95
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Coordinated regulation of Arabidopsis thaliana development by light and gibberellins. Nature (2008) 4.71
TGF-beta1-induced migration of bone mesenchymal stem cells couples bone resorption with formation. Nat Med (2009) 4.58
Sequence and analysis of rice chromosome 4. Nature (2002) 4.39
Safety and immunogenicity of an inactivated adjuvanted whole-virion influenza A (H5N1) vaccine: a phase I randomised controlled trial. Lancet (2006) 4.22
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet (2008) 4.17
Acquired copy number alterations in adult acute myeloid leukemia genomes. Proc Natl Acad Sci U S A (2009) 4.17
[Human natural infection of Plasmodium knowlesi]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2006) 3.99
Safety and immunogenicity of 2009 pandemic influenza A H1N1 vaccines in China: a multicentre, double-blind, randomised, placebo-controlled trial. Lancet (2009) 3.97
Human infection with avian influenza A H7N9 virus: an assessment of clinical severity. Lancet (2013) 3.90
An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of hand foot and mouth disease in Fuyang city of China. Virol J (2010) 3.90
Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood (2008) 3.89
Pancreatic ductal adenocarcinoma: long-term survival does not equal cure. Surgery (2012) 3.87
Seven new loci associated with age-related macular degeneration. Nat Genet (2013) 3.81
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A (2011) 3.80
Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases. Lancet (2013) 3.77
Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia. Blood (2007) 3.73
Person-to-person transmission of severe fever with thrombocytopenia syndrome virus. Vector Borne Zoonotic Dis (2011) 3.73
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Human Streptococcus suis outbreak, Sichuan, China. Emerg Infect Dis (2006) 3.65
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res (2005) 3.56
The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab (2011) 3.54
Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells. J Immunol (2007) 3.47
Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars. Nat Genet (2013) 3.41
CD4 decline and incidence of opportunistic infections in Cape Town, South Africa: implications for prophylaxis and treatment. J Acquir Immune Defic Syndr (2006) 3.39
The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer. J Biol Chem (2007) 3.38
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature (2012) 3.38
Prospective study of bevacizumab plus temozolomide in patients with advanced neuroendocrine tumors. J Clin Oncol (2012) 3.36
Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist. Science (2006) 3.26
Biological features of novel avian influenza A (H7N9) virus. Nature (2013) 3.24
Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids. J Biol Chem (2003) 3.20
Temporal relationship and predictive value of urinary acute kidney injury biomarkers after pediatric cardiopulmonary bypass. J Am Coll Cardiol (2011) 3.17
The Selaginella genome identifies genetic changes associated with the evolution of vascular plants. Science (2011) 3.10
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nat Genet (2011) 3.02
Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2. PLoS Med (2006) 2.99
Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci U S A (2004) 2.99
Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late-stage disease. Am J Hum Genet (2004) 2.97
Use of ITS2 region as the universal DNA barcode for plants and animals. PLoS One (2010) 2.92
Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance. AIDS (2009) 2.88
Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction. Circ Res (2003) 2.85
Synthesis of N-doped graphene by chemical vapor deposition and its electrical properties. Nano Lett (2009) 2.85
Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression. Ann Neurol (2011) 2.84
Dimorphic effects of Notch signaling in bone homeostasis. Nat Med (2008) 2.82
Retracted An endogenous, systemic RNAi pathway in plants. EMBO J (2010) 2.82
The Chinese free antiretroviral treatment program: challenges and responses. AIDS (2007) 2.73
Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. Nat Neurosci (2013) 2.71
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice. Proc Natl Acad Sci U S A (2005) 2.63
Adipocyte fatty acid-binding protein is a plasma biomarker closely associated with obesity and metabolic syndrome. Clin Chem (2006) 2.63
Evaluation of the impact of hepatitis B vaccination among children born during 1992-2005 in China. J Infect Dis (2009) 2.62
Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. Cell Stem Cell (2012) 2.61
Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13. Cell (2011) 2.58
Selection of aptamers for molecular recognition and characterization of cancer cells. Anal Chem (2007) 2.57
Using case vignettes to measure HIV-related stigma among health professionals in China. Int J Epidemiol (2006) 2.57
Identification and control of a poliomyelitis outbreak in Xinjiang, China. N Engl J Med (2013) 2.55
C. elegans screen identifies autophagy genes specific to multicellular organisms. Cell (2010) 2.50
Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice. Cell Metab (2013) 2.49
Colloids with valence and specific directional bonding. Nature (2012) 2.49
ZINBA integrates local covariates with DNA-seq data to identify broad and narrow regions of enrichment, even within amplified genomic regions. Genome Biol (2011) 2.47
Optimizing resource allocation in United States AIDS drug assistance programs. Clin Infect Dis (2006) 2.45