Published in J Drug Target on June 03, 2014
Hyaluronan as a therapeutic target in human diseases. Adv Drug Deliv Rev (2015) 0.81
Hyaluronan-Lysine Cisplatin Drug Carrier for Treatment of Localized Cancers: Pharmacokinetics, Tolerability, and Efficacy in Rodents and Canines. J Pharm Sci (2016) 0.80
Intratracheal Administration of Hyaluronan-Cisplatin Conjugate Nanoparticles Significantly Attenuates Lung Cancer Growth in Mice. Pharm Res (2016) 0.77
Hyaluronic acid-nimesulide conjugates as anticancer drugs against CD44-overexpressing HT-29 colorectal cancer in vitro and in vivo. Int J Nanomedicine (2017) 0.75
Development and Validation of an Inductively Coupled Plasma Mass Spectrometry (ICP-MS) Method for Quantitative Analysis of Platinum in Plasma, Urine, and Tissues. Appl Spectrosc (2016) 0.75
A Lanthanum-Tagged Chemotherapeutic Agent HA-Pt to Track the In Vivo Distribution of Hyaluronic Acid Complexes. BAOJ Pharm Sci (2015) 0.75
Phase I-II clinical trial of hyaluronan-cisplatin nanoconjugate in dogs with naturally occurring malignant tumors. Am J Vet Res (2016) 0.75
Internalized CD44s splice isoform attenuates EGFR degradation by targeting Rab7A. Proc Natl Acad Sci U S A (2017) 0.75
Hyaluronan: its nature, distribution, functions and turnover. J Intern Med (1997) 4.55
LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis. Cancer Res (2001) 2.48
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. Nat Commun (2012) 1.71
Intralymphatic chemotherapy using a hyaluronan-cisplatin conjugate. J Surg Res (2008) 1.47
Frequency of cells expressing CD44, a head and neck cancer stem cell marker: correlation with tumor aggressiveness. Head Neck (2011) 1.35
Inflammation-induced uptake and degradation of the lymphatic endothelial hyaluronan receptor LYVE-1. J Biol Chem (2007) 1.29
Hyaluronan-mediated motility: a target in oral squamous cell carcinoma. Int J Oncol (2008) 1.17
IR-780 dye loaded tumor targeting theranostic nanoparticles for NIR imaging and photothermal therapy. Biomaterials (2013) 1.14
A Phase I and pharmacological study of the platinum polymer AP5280 given as an intravenous infusion once every 3 weeks in patients with solid tumors. Clin Cancer Res (2004) 1.14
Lysosomal degradation of the carboxydextran shell of coated superparamagnetic iron oxide nanoparticles and the fate of professional phagocytes. Biomaterials (2010) 1.12
Pharmacokinetics and disposition of a localized lymphatic polymeric hyaluronan conjugate of cisplatin in rodents. J Pharm Sci (2010) 1.12
Weak base permeability characteristics influence the intracellular sequestration site in the multidrug-resistant human leukemic cell line HL-60. J Biol Chem (2004) 1.12
A novel intralymphatic nanocarrier delivery system for cisplatin therapy in breast cancer with improved tumor efficacy and lower systemic toxicity in vivo. Am J Surg (2009) 1.10
Pulmonary delivery of cisplatin-hyaluronan conjugates via endotracheal instillation for the treatment of lung cancer. Int J Pharm (2010) 1.07
Carrier-based intralymphatic cisplatin chemotherapy for the treatment of metastatic squamous cell carcinoma of the head & neck. Ther Deliv (2010) 1.00
Localized doxorubicin chemotherapy with a biopolymeric nanocarrier improves survival and reduces toxicity in xenografts of human breast cancer. J Control Release (2010) 1.00
Transferrin directed delivery of adriamycin to human cells. Anticancer Res (1998) 0.91
Fibroblasts require protein kinase C activation to respond to hyaluronan with increased locomotion. Matrix Biol (2001) 0.90
N-Boc-histidine-capped PLGA-PEG-PLGA as a smart polymer for drug delivery sensitive to tumor extracellular pH. Macromol Biosci (2010) 0.90
Liberation of doxorubicin from HPMA copolymer conjugate is essential for the induction of cell cycle arrest and nuclear fragmentation in ovarian carcinoma cells. J Control Release (2007) 0.87
Dextran derivative-based pH-sensitive liposomes for cancer immunotherapy. Biomaterials (2014) 0.86
Effects of intratumoral administration of a hyaluronan-cisplatin nanoconjugate to five dogs with soft tissue sarcomas. Am J Vet Res (2012) 0.84
Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas. Int J Oncol (2009) 0.84
Effect of modification of the physicochemical properties of ICAM-1-derived peptides on internalization and intracellular distribution in the human leukemic cell line HL-60. Mol Pharm (2009) 0.80
Adjuvant chemotherapy using cisplatin by subcutaneous administration. In Vivo (1997) 0.80
Evaluation of intracellular trafficking and clearance from HeLa cells of doxorubicin-bound block copolymers. Int J Pharm (2011) 0.79
Severe tissue necrosis after cisplatin extravasation at low concentration: possible "immediate recall phenomenon". J Natl Cancer Inst (1997) 0.78
Folate-Conjugated Polymer Micelles with pH-Triggered Drug Release Properties. Macromol Rapid Commun (2010) 0.78
[Expression of LYVE-1 and Prox-1 in non-small cell lung cancer and the relationship with lymph node metastasis]. Sichuan Da Xue Xue Bao Yi Xue Ban (2011) 0.77
Toxicity of nanomaterials. Chem Soc Rev (2011) 2.07
Effects of nanomaterial physicochemical properties on in vivo toxicity. Adv Drug Deliv Rev (2009) 1.80
Intralymphatic chemotherapy using a hyaluronan-cisplatin conjugate. J Surg Res (2008) 1.47
Importance of treatment institution in head and neck cancer radiotherapy. Otolaryngol Head Neck Surg (2009) 1.43
Nanoparticles for biomedical imaging. Expert Opin Drug Deliv (2009) 1.23
Pharmacokinetics and disposition of a localized lymphatic polymeric hyaluronan conjugate of cisplatin in rodents. J Pharm Sci (2010) 1.12
A novel intralymphatic nanocarrier delivery system for cisplatin therapy in breast cancer with improved tumor efficacy and lower systemic toxicity in vivo. Am J Surg (2009) 1.10
Flip-flop pharmacokinetics--delivering a reversal of disposition: challenges and opportunities during drug development. Ther Deliv (2011) 1.10
Functional swallowing outcomes following transoral robotic surgery vs primary chemoradiotherapy in patients with advanced-stage oropharynx and supraglottis cancers. JAMA Otolaryngol Head Neck Surg (2013) 1.09
Pulmonary delivery of cisplatin-hyaluronan conjugates via endotracheal instillation for the treatment of lung cancer. Int J Pharm (2010) 1.07
Drug delivery to the lymphatic system: importance in future cancer diagnosis and therapies. Expert Opin Drug Deliv (2009) 1.07
Physical non-viral gene delivery methods for tissue engineering. Ann Biomed Eng (2012) 1.06
Clinical toxicities of nanocarrier systems. Adv Drug Deliv Rev (2008) 1.05
Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon-caprolactone) micelles of rapamycin. Cancer Chemother Pharmacol (2007) 1.02
Biodegradable PLGA based nanoparticles for sustained regional lymphatic drug delivery. J Pharm Sci (2010) 1.01
Localized doxorubicin chemotherapy with a biopolymeric nanocarrier improves survival and reduces toxicity in xenografts of human breast cancer. J Control Release (2010) 1.00
Carrier-based intralymphatic cisplatin chemotherapy for the treatment of metastatic squamous cell carcinoma of the head & neck. Ther Deliv (2010) 1.00
Lymphatic drug delivery using engineered liposomes and solid lipid nanoparticles. Adv Drug Deliv Rev (2011) 0.97
Clinical developments in drug delivery nanotechnology. Adv Drug Deliv Rev (2008) 0.96
Formulation of a geldanamycin prodrug in mPEG-b-PCL micelles greatly enhances tolerability and pharmacokinetics in rats. J Control Release (2008) 0.94
Advances in lymphatic imaging and drug delivery. Adv Drug Deliv Rev (2011) 0.94
Reconstruction of segmental mandibular defects by distraction osteogenesis for mandibular reconstruction. Head Neck (2003) 0.93
Poly(aspartate-g-PEI800), a polyethylenimine analogue of low toxicity and high transfection efficiency for gene delivery. Biomaterials (2007) 0.93
The role of lysosomes in limiting drug toxicity in mice. J Pharmacol Exp Ther (2010) 0.91
A cremophor-free formulation for tanespimycin (17-AAG) using PEO-b-PDLLA micelles: characterization and pharmacokinetics in rats. J Pharm Sci (2009) 0.89
Prodrug strategy for PSMA-targeted delivery of TGX-221 to prostate cancer cells. Mol Pharm (2012) 0.89
Photoacoustic contrast imaging of biological tissues with nanodiamonds fabricated for high near-infrared absorbance. J Biomed Opt (2013) 0.87
Prenatal alcohol exposure reduces the size of the forelimb representation in motor cortex in rat: an intracortical microstimulation (ICMS) mapping study. Alcohol (2010) 0.86
pH-responsive Multi-PEGylated dual cationic nanoparticles enable charge modulations for safe gene delivery. ChemMedChem (2007) 0.85
Efficacy and toxicity of peritumoral delivery of nanoconjugated cisplatin in an in vivo murine model of head and neck squamous cell carcinoma. JAMA Otolaryngol Head Neck Surg (2013) 0.85
Adenovector-mediated gene delivery to human umbilical cord mesenchymal stromal cells induces inner ear cell phenotype. Cell Reprogram (2013) 0.85
A sensitive near-infrared fluorescent probe for caspase-mediated apoptosis: Synthesis and application in cell imaging. Drug Discov Ther (2011) 0.85
Effects of intratumoral administration of a hyaluronan-cisplatin nanoconjugate to five dogs with soft tissue sarcomas. Am J Vet Res (2012) 0.84
Oropharyngeal kaposi sarcoma in related persons negative for human immunodeficiency virus. Ann Otol Rhinol Laryngol (2008) 0.84
Single-step grafting of aminooxy-peptides to hyaluronan: a simple approach to multifunctional therapeutics for experimental autoimmune encephalomyelitis. J Control Release (2013) 0.84
The efficacy of anatomically based multilevel surgery for obstructive sleep apnea. Otolaryngol Head Neck Surg (2003) 0.82
Superficial temporal artery pseudoaneurysm after face lift. Aesthet Surg J (2009) 0.82
Understanding the hysteresis loop conundrum in pharmacokinetic/pharmacodynamic relationships. J Pharm Pharm Sci (2014) 0.82
Biotin-triggered release of poly(ethylene glycol)-avidin from biotinylated polyethylenimine enhances in vitro gene expression. Bioconjug Chem (2007) 0.81
Outcomes of the osteocutaneous radial forearm free flap for mandibular reconstruction. JAMA Otolaryngol Head Neck Surg (2013) 0.81
Office-based intralesional cidofovir injections for nasal septal papilloma: a pilot study. Otolaryngol Head Neck Surg (2006) 0.81
Multi-arm polymeric nanocarrier as a nitric oxide delivery platform for chemotherapy of head and neck squamous cell carcinoma. Biomaterials (2012) 0.81
In vivo efficacy of nano hyaluronan-conjugated cisplatin for treatment of murine melanoma. J Drugs Dermatol (2014) 0.80
Lysosomotropic properties of weakly basic anticancer agents promote cancer cell selectivity in vitro. PLoS One (2012) 0.80
Vorinostat with sustained exposure and high solubility in poly(ethylene glycol)-b-poly(DL-lactic acid) micelle nanocarriers: characterization and effects on pharmacokinetics in rat serum and urine. J Pharm Sci (2012) 0.80
In vivo photoacoustic imaging of chemotherapy-induced apoptosis in squamous cell carcinoma using a near-infrared caspase-9 probe. J Biomed Opt (2011) 0.80
Derp2-mutant gene vaccine inhibits airway inflammation and up-regulates Toll-like receptor 9 in an allergic asthmatic mouse model. Asian Pac J Allergy Immunol (2010) 0.80
Nanomicellar TGX221 blocks xenograft tumor growth of prostate cancer in nude mice. Prostate (2015) 0.79
Lymphatic trafficking kinetics and near-infrared imaging using star polymer architectures with controlled anionic character. Eur J Pharm Sci (2012) 0.78
Intracellular Distribution-based Anticancer Drug Targeting: Exploiting a Lysosomal Acidification Defect Associated with Cancer Cells. Mol Cell Pharmacol (2010) 0.78
Routes of administration and dose optimization of soluble antigen arrays in mice with experimental autoimmune encephalomyelitis. J Pharm Sci (2014) 0.77
High mobility group box 1 protein polymorphism affects susceptibility to recurrent pregnancy loss by up-regulating gene expression in chorionic villi. J Assist Reprod Genet (2015) 0.77
Factors influencing morbidity after surgical management of malignant thyroid disease. Ann Otol Rhinol Laryngol (2013) 0.77
Safe osteocutaneous radial forearm flap harvest with prophylactic internal fixation. Craniomaxillofac Trauma Reconstr (2011) 0.77
Targeted nanodiamonds as phenotype-specific photoacoustic contrast agents for breast cancer. Nanomedicine (Lond) (2015) 0.77
Improving viability and transfection efficiency with human umbilical cord wharton's jelly cells through use of a ROCK inhibitor. Cell Reprogram (2014) 0.77
Development of regional chemotherapies: feasibility, safety and efficacy in clinical use and preclinical studies. Ther Deliv (2011) 0.77
Lymphatic drug delivery: therapy, imaging and nanotechnology. Preface. Adv Drug Deliv Rev (2011) 0.76
Forelimb amputation-induced reorganization in the cuneate nucleus (CN) is not reflected in large-scale reorganization in rat forepaw barrel subfield cortex (FBS). Brain Res (2013) 0.76
Synchronous bilateral tonsillar squamous cell carcinoma related to human papillomavirus: Two case reports and a brief review of the literature. Ear Nose Throat J (2016) 0.76
The effects of PVP(Fe(III)) catalyst on polymer molecular weight and gene delivery via biodegradable cross-linked polyethylenimine. Pharm Res (2011) 0.75
Stereotactic body radiotherapy for treatment of squamous cell carcinoma of the tongue associated with human papilloma virus: a case report. Front Oncol (2013) 0.75
Alkyne- and 1,6-elimination- succinimidyl carbonate - terminated heterobifunctional poly(ethylene glycol) for reversible "Click" PEGylation. Drug Discov Ther (2010) 0.75
Phase I-II clinical trial of hyaluronan-cisplatin nanoconjugate in dogs with naturally occurring malignant tumors. Am J Vet Res (2016) 0.75
Spectroscopic properties and near-infrared broadband luminescence of Bi-doped SrB4O7 glasses and crystalline materials. Opt Express (2009) 0.75
Temperature dependent emission and absorption cross section of Yb3+ doped yttrium lanthanum oxide (YLO) ceramic and its application in diode pumped amplifier. Opt Express (2013) 0.75
Mandibular myofibrosarcoma of childhood: surgical resection & reconstruction with fibula flap. Braz J Otorhinolaryngol (2011) 0.75
Functional and structural organization of the forelimb representation in cuneate nucleus in rat. Brain Res (2012) 0.75