Published in Br J Pharmacol on May 01, 2014
The pharmacology of TRP channels. Br J Pharmacol (2014) 0.87
CREB, AP-1, ternary complex factors and MAP kinases connect transient receptor potential melastatin-3 (TRPM3) channel stimulation with increased c-Fos expression. Br J Pharmacol (2015) 0.82
Transient Receptor Potential Melastatin-3 (TRPM3) Mediates Nociceptive-Like Responses in Hydra vulgaris. PLoS One (2016) 0.79
Activation of gene transcription via CIM0216, a synthetic ligand of transient receptor potential melastatin-3 (TRPM3) channels. Channels (Austin) (2016) 0.75
Daily isoflurane exposure increases barbiturate insensitivity in medullary respiratory and cortical neurons via expression of ε-subunit containing GABA ARs. PLoS One (2015) 0.75
Calcium regulation of neuronal gene expression. Proc Natl Acad Sci U S A (2001) 4.31
Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons. Nature (1998) 3.13
The Concise Guide to PHARMACOLOGY 2013/14: ion channels. Br J Pharmacol (2013) 3.03
Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells. Nat Cell Biol (2008) 2.71
TRPM3 is a nociceptor channel involved in the detection of noxious heat. Neuron (2011) 2.31
Molecular and functional characterization of the melastatin-related cation channel TRPM3. J Biol Chem (2003) 1.69
Alternative splicing switches the divalent cation selectivity of TRPM3 channels. J Biol Chem (2005) 1.52
Activation of the melastatin-related cation channel TRPM3 by D-erythro-sphingosine [corrected]. Mol Pharmacol (2004) 1.49
Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice. Proc Natl Acad Sci U S A (2010) 1.46
Expression and characterization of human transient receptor potential melastatin 3 (hTRPM3). J Biol Chem (2003) 1.37
Ternary complex factors: prime nuclear targets for mitogen-activated protein kinases. Int J Biochem Cell Biol (2003) 1.36
Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice. Diabetes (2010) 1.29
Pregnenolone sulphate- and cholesterol-regulated TRPM3 channels coupled to vascular smooth muscle secretion and contraction. Circ Res (2010) 1.28
Fenamates as TRP channel blockers: mefenamic acid selectively blocks TRPM3. Br J Pharmacol (2011) 1.18
Epidermal growth factor and thrombin induced proliferation of immortalized human keratinocytes is coupled to the synthesis of Egr-1, a zinc finger transcriptional regulator. J Cell Biochem (2002) 1.14
Production of a specific extracellular inhibitor of TRPM3 channels. Br J Pharmacol (2008) 1.13
Calcium regulation of gene expression in neurons: the mode of entry matters. Curr Opin Neurobiol (1995) 1.09
The human transcriptional repressor protein NAB1: expression and biological activity. Biochim Biophys Acta (2000) 1.03
Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM3. Br J Pharmacol (2013) 0.96
Elk-1, CREB, and MKP-1 regulate Egr-1 expression in gonadotropin-releasing hormone stimulated gonadotrophs. J Cell Biochem (2008) 0.94
Rapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC5 channels. Mol Pharmacol (2011) 0.93
Cis-isomerism and other chemical requirements of steroidal agonists and partial agonists acting at TRPM3 channels. Br J Pharmacol (2010) 0.92
Transcriptional activation of the Egr-1 gene mediated by tetradecanoylphorbol acetate and extracellular signal-regulated protein kinase. Arch Biochem Biophys (2005) 0.91
Transcriptional response to muscarinic acetylcholine receptor stimulation: regulation of Egr-1 biosynthesis by ERK, Elk-1, MKP-1, and calcineurin in carbachol-stimulated human neuroblastoma cells. Arch Biochem Biophys (2007) 0.91
Inhibition of endothelial cell Ca²⁺ entry and transient receptor potential channels by Sigma-1 receptor ligands. Br J Pharmacol (2013) 0.90
Regulation and composition of activator protein 1 (AP-1) transcription factors controlling collagenase and c-Jun promoter activities. Biochem J (2001) 0.89
Substance P induced biosynthesis of the zinc finger transcription factor Egr-1 in human glioma cells requires activation of the epidermal growth factor receptor and of extracellular signal-regulated protein kinase. Neurosci Lett (2002) 0.89
Thapsigargin induces expression of activating transcription factor 3 in human keratinocytes involving Ca2+ ions and c-Jun N-terminal protein kinase. Mol Pharmacol (2010) 0.88
P2X(7) receptor stimulation upregulates Egr-1 biosynthesis involving a cytosolic Ca(2+) rise, transactivation of the EGF receptor and phosphorylation of ERK and Elk-1. J Cell Physiol (2007) 0.88
Calcium influx into MIN6 insulinoma cells induces expression of Egr-1 involving extracellular signal-regulated protein kinase and the transcription factors Elk-1 and CREB. Eur J Cell Biol (2008) 0.88
Activation of steroid-sensitive TRPM3 channels potentiates glutamatergic transmission at cerebellar Purkinje neurons from developing rats. J Neurochem (2011) 0.87
TRP channels of islets. Adv Exp Med Biol (2011) 0.87
Regulation of insulin gene transcription by the immediate-early growth response gene Egr-1. Endocrinology (2006) 0.86
TRPM3 channel stimulated by pregnenolone sulphate in synovial fibroblasts and negatively coupled to hyaluronan. BMC Musculoskelet Disord (2010) 0.85
Immediate-early transcriptional response to angiotensin II in human adrenocortical cells. Endocrinology (2011) 0.85
Regulation of pancreas duodenum homeobox-1 expression by early growth response-1. J Biol Chem (2006) 0.84
Thrombin induces Egr-1 expression in fibroblasts involving elevation of the intracellular Ca2+ concentration, phosphorylation of ERK and activation of ternary complex factor. BMC Mol Biol (2009) 0.84
Interleukin-1beta and tetradecanoylphorbol acetate-induced biosynthesis of tumor necrosis factor alpha in human hepatoma cells involves the transcription factors ATF2 and c-Jun and stress-activated protein kinases. J Cell Biochem (2007) 0.84
Signal transduction of pregnenolone sulfate in insulinoma cells: activation of Egr-1 expression involving TRPM3, voltage-gated calcium channels, ERK, and ternary complex factors. J Biol Chem (2011) 0.84
Pregnenolone sulphate-independent inhibition of TRPM3 channels by progesterone. Cell Calcium (2011) 0.83
Efficient genetic manipulation of 1321N1 astrocytoma cells using lentiviral gene transfer. J Neurosci Methods (2012) 0.83
Pregnenolone sulfate activates basic region leucine zipper transcription factors in insulinoma cells: role of voltage-gated Ca2+ channels and transient receptor potential melastatin 3 channels. Mol Pharmacol (2011) 0.83
Chromatin structure and expression of the AMPA receptor subunit Glur2 in human glioma cells: major regulatory role of REST and Sp1. J Cell Biochem (2012) 0.82
Critical role of Egr transcription factors in regulating insulin biosynthesis, blood glucose homeostasis, and islet size. Endocrinology (2012) 0.81
Signal transduction via TRPM3 channels in pancreatic β-cells. J Mol Endocrinol (2013) 0.81
The zinc finger transcription factor Egr-1 is upregulated in arsenite-treated human keratinocytes. J Mol Med (Berl) (2004) 0.80
Transcriptional response to calcium-sensing receptor stimulation. Endocrinology (2012) 0.80
Regulation of immediate-early gene transcription following activation of Gα(q)-coupled designer receptors. J Cell Biochem (2013) 0.79
Regulation of AP-1 activity in glucose-stimulated insulinoma cells. J Cell Biochem (2010) 0.78
Ca2+ signaling and gene transcription in glucose-stimulated insulinoma cells. Cell Calcium (2012) 0.76
Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation. J Biol Chem (2003) 2.04
HDAC4 controls histone methylation in response to elevated cardiac load. J Clin Invest (2013) 1.15
Neural invasion in pancreatic cancer: a mutual tropism between neurons and cancer cells. Biochem Biophys Res Commun (2008) 1.15
Epidermal growth factor and thrombin induced proliferation of immortalized human keratinocytes is coupled to the synthesis of Egr-1, a zinc finger transcriptional regulator. J Cell Biochem (2002) 1.14
Specificity of transcriptional regulation by the zinc finger transcription factors Sp1, Sp3, and Egr-1. J Cell Biochem (2005) 1.12
Regulation of asparagine synthetase gene transcription by the basic region leucine zipper transcription factors ATF5 and CHOP. Biol Chem (2005) 1.07
Opposing roles for ATF2 and c-Fos in c-Jun-mediated neuronal apoptosis. Mol Cell Biol (2009) 1.00
Egr-1 transactivates Bim gene expression to promote neuronal apoptosis. J Neurosci (2011) 0.99
Specific interaction of Egr1 and c/EBPbeta leads to the transcriptional activation of the human low density lipoprotein receptor gene. J Biol Chem (2003) 0.98
RE-1 silencing transcription factor (REST) regulates human synaptophysin gene transcription through an intronic sequence-specific DNA-binding site. Eur J Biochem (2003) 0.98
Neuroprotection of immortalized hippocampal neurones by brain-derived neurotrophic factor and Raf-1 protein kinase: role of extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase. J Neurochem (2004) 0.95
Elk-1, CREB, and MKP-1 regulate Egr-1 expression in gonadotropin-releasing hormone stimulated gonadotrophs. J Cell Biochem (2008) 0.94
CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation. Mol Cell Biol (2008) 0.94
Transcription of genes encoding synaptic vesicle proteins in human neural stem cells: chromatin accessibility, histone methylation pattern, and the essential role of rest. J Biol Chem (2008) 0.92
Transcriptional activation of the Egr-1 gene mediated by tetradecanoylphorbol acetate and extracellular signal-regulated protein kinase. Arch Biochem Biophys (2005) 0.91
Transcriptional response to muscarinic acetylcholine receptor stimulation: regulation of Egr-1 biosynthesis by ERK, Elk-1, MKP-1, and calcineurin in carbachol-stimulated human neuroblastoma cells. Arch Biochem Biophys (2007) 0.91
Dual role of NRSF/REST in activation and repression of the glucocorticoid response. J Biol Chem (2007) 0.90
Epidermal-growth-factor-induced proliferation of astrocytes requires Egr transcription factors. J Cell Sci (2009) 0.90
Regulation of gene transcription by a constitutively active mutant of activating transcription factor 2 (ATF2). Biol Chem (2003) 0.89
Substance P induced biosynthesis of the zinc finger transcription factor Egr-1 in human glioma cells requires activation of the epidermal growth factor receptor and of extracellular signal-regulated protein kinase. Neurosci Lett (2002) 0.89
Glutamate-induced cell death of immortalized murine hippocampal neurons: neuroprotective activity of heme oxygenase-1, heat shock protein 70, and sodium selenite. Neurosci Lett (2004) 0.89
Up-regulation of tyrosine hydroxylase gene transcription by tetradecanoylphorbol acetate is mediated by the transcription factors Ets-like protein-1 (Elk-1) and Egr-1. J Neurochem (2006) 0.88
Calcium influx into MIN6 insulinoma cells induces expression of Egr-1 involving extracellular signal-regulated protein kinase and the transcription factors Elk-1 and CREB. Eur J Cell Biol (2008) 0.88
Thapsigargin induces expression of activating transcription factor 3 in human keratinocytes involving Ca2+ ions and c-Jun N-terminal protein kinase. Mol Pharmacol (2010) 0.88
P2X(7) receptor stimulation upregulates Egr-1 biosynthesis involving a cytosolic Ca(2+) rise, transactivation of the EGF receptor and phosphorylation of ERK and Elk-1. J Cell Physiol (2007) 0.88
CK2 phosphorylation of Pdx-1 regulates its transcription factor activity. Cell Mol Life Sci (2010) 0.86
Expression of the transcriptional repressor ATF3 in gonadotrophs is regulated by Egr-1, CREB, and ATF2 after gonadotropin-releasing hormone receptor stimulation. Endocrinology (2008) 0.86
The protein phosphatase-1 (PP1) regulator, nuclear inhibitor of PP1 (NIPP1), interacts with the polycomb group protein, embryonic ectoderm development (EED), and functions as a transcriptional repressor. J Biol Chem (2003) 0.86
Brain-derived neurotrophic factor-, epidermal growth factor-, or A-Raf-induced growth of HaCaT keratinocytes requires extracellular signal-regulated kinase. Am J Physiol Cell Physiol (2004) 0.86
Cell type-specific regulation of RE-1 silencing transcription factor (REST) target genes. Eur J Neurosci (2005) 0.86
Neuronal cell death induced by antidepressants: lack of correlation with Egr-1, NF-kappa B and extracellular signal-regulated protein kinase activation. Biochem Pharmacol (2002) 0.85
Nitric oxide-induced programmed cell death in human neuroblastoma cells is accompanied by the synthesis of Egr-1, a zinc finger transcription factor. J Neurosci Res (2002) 0.85
Signal transduction of pregnenolone sulfate in insulinoma cells: activation of Egr-1 expression involving TRPM3, voltage-gated calcium channels, ERK, and ternary complex factors. J Biol Chem (2011) 0.84
Thrombin induces Egr-1 expression in fibroblasts involving elevation of the intracellular Ca2+ concentration, phosphorylation of ERK and activation of ternary complex factor. BMC Mol Biol (2009) 0.84
Interleukin-1beta and tetradecanoylphorbol acetate-induced biosynthesis of tumor necrosis factor alpha in human hepatoma cells involves the transcription factors ATF2 and c-Jun and stress-activated protein kinases. J Cell Biochem (2007) 0.84
Efficient genetic manipulation of 1321N1 astrocytoma cells using lentiviral gene transfer. J Neurosci Methods (2012) 0.83
Pregnenolone sulfate activates basic region leucine zipper transcription factors in insulinoma cells: role of voltage-gated Ca2+ channels and transient receptor potential melastatin 3 channels. Mol Pharmacol (2011) 0.83
ErbB2 upregulates the Na+,HCO3(-)-cotransporter NBCn1/SLC4A7 in human breast cancer cells via Akt, ERK, Src, and Kruppel-like factor 4. FASEB J (2013) 0.83
Chromatin structure and expression of the AMPA receptor subunit Glur2 in human glioma cells: major regulatory role of REST and Sp1. J Cell Biochem (2012) 0.82
The extracellular adherence protein from Staphylococcus aureus abrogates angiogenic responses of endothelial cells by blocking Ras activation. FASEB J (2006) 0.82
Hepatocyte growth factor regulates angiotensin converting enzyme expression. J Biol Chem (2003) 0.82
EGR1 expression: a calcium and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12,14-prostaglandin J2 and thiazolidinediones in breast cancer cells. Biochem Pharmacol (2011) 0.81
Egr-1 modulation of synapsin I expression: permissive effect of forskolin via cAMP. Cell Signal (2004) 0.81
Critical role of Egr transcription factors in regulating insulin biosynthesis, blood glucose homeostasis, and islet size. Endocrinology (2012) 0.81
Transcriptional response to calcium-sensing receptor stimulation. Endocrinology (2012) 0.80
Blockage of oncostatin M-induced LDL receptor gene transcription by a dominant-negative mutant of C/EBPbeta. Biochem J (2006) 0.80
Regulation of GTP cyclohydrolase I gene transcription by basic region leucine zipper transcription factors. J Cell Biochem (2005) 0.80
Chromatin structure and expression of synapsin I and synaptophysin in retinal precursor cells. Neurochem Int (2008) 0.80
The zinc finger transcription factor Egr-1 is upregulated in arsenite-treated human keratinocytes. J Mol Med (Berl) (2004) 0.80
Regulation of immediate-early gene transcription following activation of Gα(q)-coupled designer receptors. J Cell Biochem (2013) 0.79
RE-1 silencing transcription factor-4 (REST4) is neither a transcriptional repressor nor a de-repressor. Neurochem Int (2002) 0.79
Expression of the transcription factor Egr-1 in pancreatic acinar cells following stimulation of cholecystokinin or Gαq-coupled designer receptors. Cell Physiol Biochem (2014) 0.79
Regulation of AP-1 activity in glucose-stimulated insulinoma cells. J Cell Biochem (2010) 0.78
Tissue-specific regulatory network extractor (TS-REX): a database and software resource for the tissue and cell type-specific investigation of transcription factor-gene networks. Nucleic Acids Res (2009) 0.78
Characterization of the bovine angiotensin converting enzyme promoter: essential roles of Egr-1, ATF-2 and Ets-1 in the regulation by phorbol ester. Gene (2008) 0.78
G-protein-coupled designer receptors - new chemical-genetic tools for signal transduction research. Biol Chem (2013) 0.77
Signal transduction--receptors, mediators, and genes. Sci Signal (2009) 0.77
Ca2+ signaling and gene transcription in glucose-stimulated insulinoma cells. Cell Calcium (2012) 0.76
The 2009 meeting of the study group 'Molecular Neurobiology' of the German Society for Biochemistry and Molecular Biology. Biol Chem (2010) 0.75
Role of c-Jun concentration in neuronal cell death. J Neurosci Res (2002) 0.75
Transforming growth factor-beta and tumor necrosis factor-alpha cooperate to induce apoptosis in the oligodendroglial cell line OLI-neu. J Neurosci Res (2003) 0.75
Lack of correlation between NF-kappaB activation and induction of programmed cell death in PC12 pheochromocytoma cells treated with 6-hydroxydopamine or the cannabinoid receptor 1-agonist CP55,940. Biochem Pharmacol (2002) 0.75
Signal transduction in the footsteps of goethe and schiller. Cell Commun Signal (2009) 0.75