Gd Complexes of DO3A-(Biphenyl-2,2'-bisamides) Conjugates as MRI Blood-Pool Contrast Agents.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 4025651)

Published in ACS Med Chem Lett on October 23, 2012

Authors

Ki-Hye Jung1, Hee-Kyung Kim1, Ji-Ae Park2, Ki Soo Nam1, Gang Ho Lee1, Yongmin Chang3, Tae-Jeong Kim1

Author Affiliations

1: Department of Applied Chemistry, Department of Medical & Biological Engineering, and Department of Chemistry, Kyungpook National University , University Road 80, Daegu, 702-701, Korea.
2: Molecular Imaging Research Center, Korea Institute of Radiological Medical Science , Nowon-gil 75, Seoul, 139-706, Korea.
3: Department of Applied Chemistry, Department of Medical & Biological Engineering, and Department of Chemistry, Kyungpook National University , University Road 80, Daegu, 702-701, Korea ; Department of Radiology & Molecular Medicine, Kyungpook National University , Dongin-dong 2-ga, Daegu, 700-422, Korea.

Articles cited by this

Gadolinium(III) Chelates as MRI Contrast Agents: Structure, Dynamics, and Applications. Chem Rev (1999) 12.52

Strategies for increasing the sensitivity of gadolinium based MRI contrast agents. Chem Soc Rev (2006) 4.27

Physical and chemical properties of superparamagnetic iron oxide MR contrast agents: ferumoxides, ferumoxtran, ferumoxsil. Magn Reson Imaging (1995) 2.67

The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates. J Am Chem Soc (2002) 2.28

MS-325: albumin-targeted contrast agent for MR angiography. Radiology (1998) 1.98

3D-micro-MR angiography of mice using macromolecular MR contrast agents with polyamidoamine dendrimer core with reference to their pharmacokinetic properties. Magn Reson Med (2001) 1.49

Stability of MRI paramagnetic contrast media: a proton relaxometric protocol for transmetallation assessment. Invest Radiol (2001) 1.48

MR angiography with blood pool contrast agents. Eur Radiol (2007) 1.28

Long-circulating liposomal contrast agents for magnetic resonance imaging. Magn Reson Med (2006) 1.17

Ternary Gd(III)L-HSA adducts: evidence for the replacement of inner-sphere water molecules by coordinating groups of the protein. Implications for the design of contrast agents for MRI. J Biol Inorg Chem (2000) 1.09

MRI monitoring of Avastin antiangiogenesis therapy using B22956/1, a new blood pool contrast agent, in an experimental model of human cancer. J Magn Reson Imaging (2004) 1.02

Polylysine-Gd-DTPAn and polylysine-Gd-DOTAn coupled to anti-CEA F(ab')2 fragments as potential immunocontrast agents. Relaxometry, biodistribution, and magnetic resonance imaging in nude mice grafted with human colorectal carcinoma. Invest Radiol (1998) 0.99

New generation of monomer-stabilized very small superparamagnetic iron oxide particles (VSOP) as contrast medium for MR angiography: preclinical results in rats and rabbits. J Magn Reson Imaging (2000) 0.96

Maximizing the relaxivity of HSA-bound gadolinium complexes by simultaneous optimization of rotation and water exchange. Chem Commun (Camb) (2007) 0.94

Tumor angiography using high-resolution, three-dimensional magnetic resonance imaging: comparison of gadopentetate dimeglumine and a macromolecular blood-pool contrast agent. Acad Radiol (1995) 0.89

Novel paramagnetic macromolecular complexes derived from the linkage of a macrocyclic Gd(III) complex to polyamino acids through a squaric acid moiety. Bioconjug Chem (1999) 0.85

Gd complexes of macrocyclic diethylenetriaminepentaacetic acid (DTPA) biphenyl-2,2'-bisamides as strong blood-pool magnetic resonance imaging contrast agents. J Med Chem (2011) 0.85

pH-sensitive paramagnetic liposomes as MRI contrast agents: in vitro feasibility studies. Magn Reson Imaging (2001) 0.82

Comprehensive investigation of the non-covalent binding of MRI contrast agents with human serum albumin. J Biol Inorg Chem (2007) 0.81

Preclinical profile and clinical potential of gadocoletic acid trisodium salt (B22956/1), a new intravascular contrast medium for MRI. Acad Radiol (2002) 0.80

Gd-complexes of macrocyclic DTPA conjugates of 1,1'-bis(amino)ferrocenes as high relaxivity MRI blood-pool contrast agents (BPCAs). Chem Commun (Camb) (2010) 0.77