Published in Apoptosis on September 01, 2014
A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2. J Biol Chem (2014) 0.86
Time-Resolved Study of Nanoparticle Induced Apoptosis Using Microfabricated Single Cell Arrays. Microarrays (Basel) (2016) 0.75
Institutional profile: the national Swedish academic drug discovery & development platform at SciLifeLab. Future Sci OA (2017) 0.75
Inhibition of proteasome deubiquitinating activity as a new cancer therapy. Nat Med (2011) 4.09
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia. Genome Biol (2013) 1.57
Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination. Leuk Lymphoma (2008) 1.54
The mutational landscape in pediatric acute lymphoblastic leukemia deciphered by whole genome sequencing. Hum Mutat (2015) 1.46
Coagulation, fibrinolysis, and cell activation in patients and shed mediastinal blood during coronary artery bypass grafting with a new heparin-coated surface. J Thorac Cardiovasc Surg (2002) 1.44
DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia. Blood (2009) 1.42
The fluorometric microculture cytotoxicity assay. Nat Protoc (2008) 1.36
Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells. Nucleic Acids Res (2007) 1.36
Cyclotides: a novel type of cytotoxic agents. Mol Cancer Ther (2002) 1.32
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. J Med Chem (2008) 1.32
Aminopeptidase N (CD13) as a target for cancer chemotherapy. Cancer Sci (2011) 1.30
Characterization of the cytotoxic properties of the benzimidazole fungicides, benomyl and carbendazim, in human tumour cell lines and primary cultures of patient tumour cells. Anticancer Drugs (2010) 1.25
Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation. Diabetes (2007) 1.24
Polycomb target genes are silenced in multiple myeloma. PLoS One (2010) 1.21
ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing. PLoS One (2011) 1.21
Optimal heparin surface concentration and antithrombin binding capacity as evaluated with human non-anticoagulated blood in vitro. J Biomed Mater Res A (2003) 1.19
Cytotoxic cyclotides from Viola tricolor. J Nat Prod (2004) 1.18
Selective cytotoxicity evaluation in anticancer drug screening of fractionated plant extracts. J Biomol Screen (2002) 1.18
C3 adsorbed to a polymer surface can form an initiating alternative pathway convertase. J Immunol (2002) 1.13
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo. Int J Cancer (2012) 1.13
Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients. Biochem Pharmacol (2006) 1.12
Antimicrobial and cytotoxic activity of agelasine and agelasimine analogs. Bioorg Med Chem (2007) 1.11
High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation. Mol Cell Proteomics (2009) 1.10
STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines. Int J Cancer (2007) 1.09
Molecular markers for discrimination of benign and malignant follicular thyroid tumors. Tumour Biol (2006) 1.09
Safety and efficacy of NAD depleting cancer drugs: results of a phase I clinical trial of CHS 828 and overview of published data. Cancer Chemother Pharmacol (2009) 1.08
Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs. J Nat Prod (2009) 1.07
Inhibition of proteasome activity, nuclear factor-KappaB translocation and cell survival by the antialcoholism drug disulfiram. Int J Cancer (2006) 1.07
Supervised identification of allergen-representative peptides for in silico detection of potentially allergenic proteins. Bioinformatics (2004) 1.07
Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system. Exp Cell Res (2012) 1.06
Bayesian detection of periodic mRNA time profiles without use of training examples. BMC Bioinformatics (2006) 1.05
Piperlongumine induces inhibition of the ubiquitin-proteasome system in cancer cells. Biochem Biophys Res Commun (2013) 1.01
Effects of hypoxia on human cancer cell line chemosensitivity. BMC Cancer (2013) 1.00
Anticancer agent CHS 828 suppresses nuclear factor-kappa B activity in cancer cells through downregulation of IKK activity. Int J Cancer (2004) 0.99
Prediction of food protein allergenicity: a bioinformatic learning systems approach. In Silico Biol (2002) 0.98
Induction of the lysosomal apoptosis pathway by inhibitors of the ubiquitin-proteasome system. Int J Cancer (2009) 0.98
Multiparametric evaluation of apoptosis: effects of standard cytotoxic agents and the cyanoguanidine CHS 828. Mol Cancer Ther (2004) 0.96
Unbiased descriptor and parameter selection confirms the potential of proteochemometric modelling. BMC Bioinformatics (2005) 0.96
In vitro activity of bortezomib in cultures of patient tumour cells--potential utility in haematological malignancies. Med Oncol (2008) 0.94
A Phase I study of CHS 828 in patients with solid tumor malignancy. Clin Cancer Res (2002) 0.94
Screening of an annotated compound library for drug activity in a resistant myeloma cell line. Cancer Chemother Pharmacol (2006) 0.93
Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer. J Cancer Res Clin Oncol (2013) 0.93
(+)-agelasine D: improved synthesis and evaluation of antibacterial and cytotoxic activities. J Nat Prod (2006) 0.91
Evaluation of the blood compatibility of materials, cells, and tissues: basic concepts, test models, and practical guidelines. Adv Exp Med Biol (2013) 0.90
The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death. Mol Pharmacol (2014) 0.90
Induction of tumor cell apoptosis by a proteasome deubiquitinase inhibitor is associated with oxidative stress. Antioxid Redox Signal (2013) 0.90
Towards high-throughput single cell/clone cultivation and analysis. Electrophoresis (2008) 0.89
Significant cytotoxic activity in vitro of the EGFR tyrosine kinase inhibitor gefitinib in acute myeloblastic leukaemia. Eur J Haematol (2008) 0.89
Image-based screening for the identification of novel proteasome inhibitors. J Biomol Screen (2007) 0.89
Improved variance estimation of classification performance via reduction of bias caused by small sample size. BMC Bioinformatics (2006) 0.88
Identification of agents that induce apoptosis of multicellular tumour spheroids: enrichment for mitotic inhibitors with hydrophobic properties. Chem Biol Drug Des (2011) 0.88
Identification and evaluation of potential anti-cancer drugs on human neuroendocrine tumor cell lines. Anticancer Res (2007) 0.88
Antitumor efficacy and acute toxicity of the novel dipeptide melphalanyl-p-L-fluorophenylalanine ethyl ester (J1) in vivo. Invest New Drugs (2004) 0.88
Multivariate statistical analysis of large-scale IgE antibody measurements reveals allergen extract relationships in sensitized individuals. J Allergy Clin Immunol (2007) 0.88
Cytotoxicity and pharmacokinetics of cladribine metabolite, 2-chloroadenine in patients with leukemia. Cancer Lett (2004) 0.88
Novel activity of acriflavine against colorectal cancer tumor cells. Cancer Sci (2011) 0.87
Increased in vitro cellular drug resistance is related to poor outcome in high-risk childhood acute lymphoblastic leukaemia. Br J Haematol (2003) 0.86
Action of a novel anticancer agent, CHS 828, on mouse fibroblasts: increased sensitivity of cells lacking poly (ADP-Ribose) polymerase-1. Cancer Res (2002) 0.86
Drug repositioning from bench to bedside: tumour remission by the antihelmintic drug mebendazole in refractory metastatic colon cancer. Acta Oncol (2013) 0.86
Modulation of pyridyl cyanoguanidine (CHS 828) induced cytotoxicity by 3-aminobenzamide in U-937 GTB cells. Biochem Pharmacol (2002) 0.86
Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma. BMC Cancer (2012) 0.85
EVALLER: a web server for in silico assessment of potential protein allergenicity. Nucleic Acids Res (2007) 0.85
Identification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transporters. PLoS One (2009) 0.85
Gene expression profiles in mouse lung tissue after administration of two cationic polymers used for nonviral gene delivery. Pharm Res (2006) 0.85
Alpha terpineol: a potential anticancer agent which acts through suppressing NF-kappaB signalling. Anticancer Res (2010) 0.85
The novel melphalan prodrug J1 inhibits neuroblastoma growth in vitro and in vivo. Mol Cancer Ther (2007) 0.85
Activity of hydrolytic enzymes in tumour cells is a determinant for anti-tumour efficacy of the melphalan containing prodrug J1. J Drug Target (2003) 0.85
Assessing relative bioactivity of chemical substances using quantitative molecular network topology analysis. J Chem Inf Model (2012) 0.84
Translocation t(12;21) is related to in vitro cellular drug sensitivity to doxorubicin and etoposide in childhood acute lymphoblastic leukemia. Blood (2004) 0.84
Bioactive heparin immobilized onto microfluidic channels in poly(dimethylsiloxane) results in hydrophilic surface properties. Colloids Surf B Biointerfaces (2005) 0.84
The alkylating prodrug J1 can be activated by aminopeptidase N, leading to a possible target directed release of melphalan. Biochem Pharmacol (2010) 0.84
Phenotype-based screening of mechanistically annotated compounds in combination with gene expression and pathway analysis identifies candidate drug targets in a human squamous carcinoma cell model. J Biomol Screen (2006) 0.84
Automated QuantMap for rapid quantitative molecular network topology analysis. Bioinformatics (2013) 0.84
Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis. Tissue Eng Part A (2010) 0.84
Measuring the degree of plasma contact activation induced by artificial materials. Thromb Res (2002) 0.84
In vitro evaluation of clinical activity and toxicity of anticancer drugs using tumor cells from patients and cells representing normal tissues. Cancer Chemother Pharmacol (2011) 0.84