Published in Immunity on June 12, 2014
Schizophrenia interactome with 504 novel protein-protein interactions. NPJ Schizophr (2016) 1.40
OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines. Genome Res (2014) 1.09
RIG-I-like receptor regulation in virus infection and immunity. Curr Opin Virol (2015) 1.07
ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA. Elife (2015) 0.98
Central role of ULK1 in type I interferon signaling. Cell Rep (2015) 0.90
Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases. Exp Mol Med (2015) 0.89
Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses. Proc Natl Acad Sci U S A (2016) 0.86
Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types. Front Immunol (2014) 0.85
Shared signatures between rheumatoid arthritis, systemic lupus erythematosus and Sjögren's syndrome uncovered through gene expression meta-analysis. Arthritis Res Ther (2014) 0.84
Interferons and the Immunogenic Effects of Cancer Therapy. Trends Immunol (2015) 0.84
OASL-a new player in controlling antiviral innate immunity. Curr Opin Virol (2015) 0.83
Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3. Proc Natl Acad Sci U S A (2015) 0.83
ADAR1 Suppresses the Activation of Cytosolic RNA-Sensing Signaling Pathways to Protect the Liver from Ischemia/Reperfusion Injury. Sci Rep (2016) 0.81
Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape. PLoS Genet (2015) 0.80
Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase Activity. J Virol (2016) 0.80
ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry. PLoS Pathog (2015) 0.79
Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling. Nucleic Acids Res (2015) 0.79
2'-5'-Oligoadenylate Synthetase-Like Protein Inhibits Respiratory Syncytial Virus Replication and Is Targeted by the Viral Nonstructural Protein 1. J Virol (2015) 0.78
Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State. Antimicrob Agents Chemother (2016) 0.77
MOV10 Provides Antiviral Activity against RNA Viruses by Enhancing RIG-I-MAVS-Independent IFN Induction. J Immunol (2016) 0.77
The Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate Response. Int J Mol Sci (2016) 0.76
Could boosting the oligoadenylate synthetase-like pathway bring a new era of antiviral therapy? Future Virol (2015) 0.75
Quantitative Proteomic Analysis of Duck Ovarian Follicles Infected with Duck Tembusu Virus by Label-Free LC-MS. Front Microbiol (2016) 0.75
Unique nonstructural proteins of Pneumonia Virus of Mice (PVM) promote degradation of interferon (IFN) pathway components and IFN-stimulated gene proteins. Sci Rep (2016) 0.75
The dynamic interacting landscape of MAPL reveals essential functions for SUMOylation in innate immunity. Sci Rep (2017) 0.75
What is the oligoadenylate synthetases-like protein and does it have therapeutic potential for influenza? Expert Rev Respir Med (2014) 0.75
Identification of Interferon-Stimulated Gene Proteins That Inhibit Human Parainfluenza Virus Type 3. J Virol (2016) 0.75
Host and Viral Modulation of RIG-I-Mediated Antiviral Immunity. Front Immunol (2017) 0.75
Translation inhibition and stress granules in the antiviral immune response. Nat Rev Immunol (2017) 0.75
Genomic Programming of Human Neonatal Dendritic Cells in Congenital Systemic and In Vitro Cytomegalovirus Infection Reveal Plastic and Robust Immune Pathway Biology Responses. Front Immunol (2017) 0.75
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol (2004) 26.12
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature (2006) 22.65
Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A (2013) 16.74
A diverse range of gene products are effectors of the type I interferon antiviral response. Nature (2011) 12.86
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science (2012) 10.47
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell (2009) 10.11
Interferon-inducible antiviral effectors. Nat Rev Immunol (2008) 9.68
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature (2007) 8.87
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. Nat Immunol (2009) 6.97
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell (2010) 5.83
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe (2009) 5.12
Immune signaling by RIG-I-like receptors. Immunity (2011) 5.02
Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity. Nature (2013) 4.45
Viral evasion and subversion of pattern-recognition receptor signalling. Nat Rev Immunol (2008) 4.16
Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Cell (2011) 4.11
Structural insights into RNA recognition by RIG-I. Cell (2011) 3.25
Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science (2013) 3.10
Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response. Immunity (2012) 3.07
Structural basis of RNA recognition and activation by innate immune receptor RIG-I. Nature (2011) 3.05
Intrinsic antiviral immunity. Nat Immunol (2012) 2.71
Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5. Cell (2012) 2.34
Novel functions of proteins encoded by viral stress-inducible genes. Pharmacol Ther (2004) 2.25
Positional cloning of the murine flavivirus resistance gene. Proc Natl Acad Sci U S A (2002) 2.22
Systematic identification of type I and type II interferon-induced antiviral factors. Proc Natl Acad Sci U S A (2012) 2.18
Viral tricks to grid-lock the type I interferon system. Curr Opin Microbiol (2010) 2.17
Single nucleotide polymorphisms in genes for 2'-5'-oligoadenylate synthetase and RNase L inpatients hospitalized with West Nile virus infection. J Infect Dis (2005) 2.11
Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition. Proc Natl Acad Sci U S A (2011) 1.99
A ligation-independent cloning technique for high-throughput assembly of transcription activator–like effector genes. Nat Biotechnol (2013) 1.98
OASL1 inhibits translation of the type I interferon-regulating transcription factor IRF7. Nat Immunol (2013) 1.87
The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. J Interferon Cytokine Res (2010) 1.59
RIG-I forms signaling-competent filaments in an ATP-dependent, ubiquitin-independent manner. Mol Cell (2013) 1.57
Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity. PLoS One (2012) 1.55
ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon. EMBO Rep (2013) 1.54
The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling. EMBO Rep (2011) 1.47
Regulation of mitochondrial antiviral signaling pathways. Immunity (2008) 1.44
p59OASL, a 2'-5' oligoadenylate synthetase like protein: a novel human gene related to the 2'-5' oligoadenylate synthetase family. Nucleic Acids Res (1998) 1.17
PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin. EMBO J (2011) 1.13
Differential regulation of the OASL and OAS1 genes in response to viral infections. J Interferon Cytokine Res (2009) 1.13
Genetic and phenotypic characterization of sylvatic dengue virus type 2 strains. Virology (2008) 1.04
The powerstroke and camshaft of the RIG-I antiviral RNA detection machine. Cell (2011) 1.04
Molecular cloning and characterization of two related and interferon-induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase. Eur J Biochem (1998) 1.03
The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain. J Gen Virol (2008) 1.02
Characterization of the 2'-5'-oligoadenylate synthetase ubiquitin-like family. Nucleic Acids Res (2003) 1.01
Viral degradasome hijacks mitochondria to suppress innate immunity. Cell Res (2013) 0.99
Structural insights into the activation of RIG-I, a nanosensor for viral RNAs. EMBO Rep (2011) 0.97
Ubiquitin-mediated modulation of the cytoplasmic viral RNA sensor RIG-I. J Biochem (2011) 0.94
Candidate genes responsible for human hepatocellular carcinoma identified from differentially expressed genes in hepatocarcinogenesis of the tree shrew (Tupaia belangeri chinesis). Hepatol Res (2007) 0.84