Published in PLoS One on June 16, 2014
Neonatal exposure to sevoflurane may not cause learning and memory deficits and behavioral abnormality in the childhood of Cynomolgus monkeys. Sci Rep (2015) 0.83
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Efficacy of rutin in inhibiting neuronal apoptosis and cognitive disturbances in sevoflurane or propofol exposed neonatal mice. Int J Clin Exp Med (2015) 0.76
Effects of propofol versus sevoflurane on cerebral oxygenation and cognitive outcome in patients with impaired cerebral oxygenation. Ther Clin Risk Manag (2016) 0.76
Propofol Affects Neurodegeneration and Neurogenesis by Regulation of Autophagy via Effects on Intracellular Calcium Homeostasis. Anesthesiology (2017) 0.76
Repeated brief isoflurane anesthesia during early postnatal development produces negligible changes on adult behavior in male mice. PLoS One (2017) 0.75
Propofol-Induced Neurotoxicity in the Fetal Animal Brain and Developments in Modifying These Effects-An Updated Review of Propofol Fetal Exposure in Laboratory Animal Studies. Brain Sci (2016) 0.75
TNF-α receptor antagonist attenuates isoflurane-induced cognitive impairment in aged rats. Exp Ther Med (2016) 0.75
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General Anesthetics Regulate Autophagy via Modulating the Inositol 1,4,5-Trisphosphate Receptor: Implications for Dual Effects of Cytoprotection and Cytotoxicity. Sci Rep (2017) 0.75
Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci (2003) 7.42
Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain. Anesthesiology (2010) 4.44
Cognitive and behavioral outcomes after early exposure to anesthesia and surgery. Pediatrics (2011) 3.76
Inhibition of p75 neurotrophin receptor attenuates isoflurane-mediated neuronal apoptosis in the neonatal central nervous system. Anesthesiology (2009) 3.26
Ketamine-induced neuronal cell death in the perinatal rhesus monkey. Toxicol Sci (2007) 3.22
Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline. Proc Natl Acad Sci U S A (2010) 2.70
The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo. Ann Neurol (2008) 2.54
Comparison of the neuroapoptotic properties of equipotent anesthetic concentrations of desflurane, isoflurane, or sevoflurane in neonatal mice. Anesthesiology (2011) 2.42
Characterization and quantification of isoflurane-induced developmental apoptotic cell death in mouse cerebral cortex. Anesth Analg (2013) 2.41
Isoflurane causes greater neurodegeneration than an equivalent exposure of sevoflurane in the developing brain of neonatal mice. Anesthesiology (2010) 2.08
Subanesthetic doses of propofol induce neuroapoptosis in the infant mouse brain. Anesth Analg (2008) 1.96
Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. Anesthesiology (2013) 1.93
Resolving postoperative neuroinflammation and cognitive decline. Ann Neurol (2011) 1.92
Effect of hypercarbia and isoflurane on brain cell death and neurocognitive dysfunction in 7-day-old rats. Anesthesiology (2009) 1.82
Xenon mitigates isoflurane-induced neuronal apoptosis in the developing rodent brain. Anesthesiology (2007) 1.80
The common inhalational anesthetic isoflurane induces apoptosis via activation of inositol 1,4,5-trisphosphate receptors. Anesthesiology (2008) 1.79
Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory. Ann Neurol (2012) 1.76
Isoflurane-induced apoptosis of oligodendrocytes in the neonatal primate brain. Ann Neurol (2012) 1.70
Dual effects of isoflurane on proliferation, differentiation, and survival in human neuroprogenitor cells. Anesthesiology (2013) 1.68
Neonatal desflurane exposure induces more robust neuroapoptosis than do isoflurane and sevoflurane and impairs working memory. Anesthesiology (2011) 1.68
Early childhood general anaesthesia exposure and neurocognitive development. Br J Anaesth (2010) 1.67
The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β. Neurobiol Aging (2010) 1.62
Developmental neurotoxicity of sedatives and anesthetics: a concern for neonatal and pediatric critical care medicine? Pediatr Crit Care Med (2010) 1.62
Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain. Anesthesiology (2012) 1.59
Inhalational anesthetics induce cell damage by disruption of intracellular calcium homeostasis with different potencies. Anesthesiology (2008) 1.52
Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain. Neurobiol Dis (2005) 1.52
Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain. Acta Anaesthesiol Scand (2009) 1.50
Propofol limits microglial activation after experimental brain trauma through inhibition of nicotinamide adenine dinucleotide phosphate oxidase. Anesthesiology (2013) 1.49
Isoflurane induces hippocampal cell injury and cognitive impairments in adult rats. Neuropharmacology (2011) 1.47
Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain. Br J Anaesth (2013) 1.47
Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci (2008) 1.44
Anesthesia, calcium homeostasis and Alzheimer's disease. Curr Alzheimer Res (2009) 1.37
General anesthesia causes long-lasting disturbances in the ultrastructural properties of developing synapses in young rats. Neurotox Res (2009) 1.37
Neurotransmitters and apoptosis in the developing brain. Biochem Pharmacol (2001) 1.37
General Anesthesia Causes Long-term Impairment of Mitochondrial Morphogenesis and Synaptic Transmission in Developing Rat Brain. Anesthesiology (2011) 1.36
Reliability of S100B in predicting severity of central nervous system injury. Neurocrit Care (2007) 1.34
Effects of fetal exposure to isoflurane on postnatal memory and learning in rats. Neuropharmacology (2007) 1.31
Inhalation anesthetic-induced neuronal damage in the developing rhesus monkey. Neurotoxicol Teratol (2011) 1.30
Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation. Anesthesiology (2012) 1.21
A presenilin-1 mutation renders neurons vulnerable to isoflurane toxicity. Anesth Analg (2008) 1.18
Anesthetic-induced neurodegeneration mediated via inositol 1,4,5-trisphosphate receptors. J Pharmacol Exp Ther (2010) 1.17
Repeated exposure to propofol potentiates neuroapoptosis and long-term behavioral deficits in neonatal rats. Neurosci Lett (2013) 1.13
Isoflurane induces learning impairment that is mediated by interleukin 1β in rodents. PLoS One (2012) 1.11
Anesthesia-induced neurodegeneration in fetal rat brains. Pediatr Res (2009) 1.07
The effects of L-carnitine on the combination of, inhalation anesthetic-induced developmental, neuronal apoptosis in the rat frontal cortex. Neuroscience (2007) 1.06
GABAergic excitotoxicity injury of the immature hippocampal pyramidal neurons' exposure to isoflurane. Anesth Analg (2011) 1.06
Ketamine activates cell cycle signaling and apoptosis in the neonatal rat brain. Anesthesiology (2010) 1.04
Surgery results in exaggerated and persistent cognitive decline in a rat model of the Metabolic Syndrome. Anesthesiology (2013) 1.03
Neurological biomarkers in the perioperative period. Br J Anaesth (2011) 0.98
Pyrrolidine dithiocarbamate attenuates surgery-induced neuroinflammation and cognitive dysfunction possibly via inhibition of nuclear factor κB. Neuroscience (2013) 0.97
Lower isoflurane concentration affects spatial learning and neurodegeneration in adult mice compared with higher concentrations. Anesthesiology (2010) 0.95
The role of calcium dysregulation in anesthetic-mediated neurotoxicity. Anesth Analg (2011) 0.95
Modulation of murine Alzheimer pathogenesis and behavior by surgery. Ann Surg (2013) 0.94
Inhaled sevoflurane may promote progression of amnestic mild cognitive impairment: a prospective, randomized parallel-group study. Am J Med Sci (2013) 0.94
The common inhaled anesthetic isoflurane increases aggregation of huntingtin and alters calcium homeostasis in a cell model of Huntington's disease. Toxicol Appl Pharmacol (2010) 0.89
The toxic effects of s(+)-ketamine on differentiating neurons in vitro as a consequence of suppressed neuronal Ca2+ oscillations. Anesth Analg (2011) 0.88
Propofol protects against focal cerebral ischemia via inhibition of microglia-mediated proinflammatory cytokines in a rat model of experimental stroke. PLoS One (2013) 0.88
Propofol's effects on phagocytosis, proliferation, nitrate production, and cytokine secretion in pressure-stimulated microglial cells. Surgery (2011) 0.87
Anesthetic modulation of neuroinflammation in Alzheimer's disease. Curr Opin Anaesthesiol (2011) 0.86
Propofol induces neuronal apoptosis in infant rat brain under hypoxic conditions. Brain Res Bull (2011) 0.83