Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scattering.

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Published in Nat Chem on May 25, 2014

Authors

Dan Fu1, Jing Zhou2, Wenjing Suzanne Zhu3, Paul W Manley4, Y Karen Wang3, Tami Hood3, Andrew Wylie3, X Sunney Xie5

Author Affiliations

1: 1] Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA [2].
2: 1] Novartis Institute for Biomedical Research, Cambridge, Massachusetts 02139, USA [2].
3: Novartis Institute for Biomedical Research, Cambridge, Massachusetts 02139, USA.
4: Novartis Institute for Biomedical Research, Basel CH-4002, Switzerland.
5: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Associated clinical trials:

Trial of Imatinib for Hospitalized Adults With COVID-19 | NCT04394416

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