MicroRNA-196a and -196b as Potential Biomarkers for the Early Detection of Familial Pancreatic Cancer.

PubWeight™: 1.00‹?› | Rank: Top 15%

🔗 View Article (PMC 4202799)

Published in Transl Oncol on June 21, 2014

Authors

Emily P Slater1, Konstantin Strauch2, Susanne Rospleszcz2, Annette Ramaswamy3, Irene Esposito4, Günter Klöppel4, Elvira Matthäi5, Kristin Heeger5, Volker Fendrich5, Peter Langer5, Detlef K Bartsch5

Author Affiliations

1: Department of Surgery, Philipps University of Marburg, Marburg, Germany. Electronic address: slater@med.uni-marburg.de.
2: Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
3: Department of Pathology, Philipps University of Marburg, Marburg, Germany.
4: Institute of Pathology, Technical University of Munich, Munich, Germany.
5: Department of Surgery, Philipps University of Marburg, Marburg, Germany.

Articles citing this

Circulating RNAs as new biomarkers for detecting pancreatic cancer. World J Gastroenterol (2015) 1.01

Clinical implications of miRNAs in the pathogenesis, diagnosis and therapy of pancreatic cancer. Adv Drug Deliv Rev (2014) 1.00

MicroRNA in pancreatic ductal adenocarcinoma and its precursor lesions. World J Gastrointest Oncol (2016) 0.87

MicroRNA Targeted Therapeutic Approach for Pancreatic Cancer. Int J Biol Sci (2016) 0.84

miR-196, an Emerging Cancer Biomarker for Digestive Tract Cancers. J Cancer (2016) 0.82

Application of a Serum Protein Signature for Pancreatic Cancer to Separate Cases from Controls in a Pancreatic Surveillance Cohort. Transl Oncol (2016) 0.81

Liquid biopsy in patients with pancreatic cancer: Circulating tumor cells and cell-free nucleic acids. World J Gastroenterol (2016) 0.80

New combined microRNA and protein plasmatic biomarker panel for pancreatic cancer. Oncotarget (2016) 0.79

Noncoding RNAs as novel biomarkers in pancreatic cancer: what do we know? Future Oncol (2016) 0.78

Plasma miR-15b-5p, miR-338-5p, and miR-764 as Biomarkers for Hepatocellular Carcinoma. Med Sci Monit (2015) 0.77

miRNAs As Diagnostic and Prognostic Biomarkers in Pancreatic Ductal Adenocarcinoma and Its Precursor Lesions: A Review. Biomark Insights (2015) 0.76

High Expression of MicroRNA-196a Indicates Poor Prognosis in Resected Pancreatic Neuroendocrine Tumor. Medicine (Baltimore) (2015) 0.76

Methods and outcomes of screening for pancreatic adenocarcinoma in high-risk individuals. World J Gastrointest Endosc (2015) 0.76

Dilemmas in the management of screen-detected lesions in patients at high risk for pancreatic cancer. Fam Cancer (2017) 0.75

Clinically relevant circulating microRNA profiling studies in pancreatic cancer using meta-analysis. Oncotarget (2017) 0.75

Molecular Imaging with MRI: Potential Application in Pancreatic Cancer. Biomed Res Int (2015) 0.75

Novel biomarkers and endoscopic techniques for diagnosing pancreaticobiliary malignancy. F1000Res (2017) 0.75

Articles cited by this

Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer (2006) 46.47

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell (2003) 15.43

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell (2005) 14.21

MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA (2007) 9.97

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature (1985) 9.78

Serum microRNAs are promising novel biomarkers. PLoS One (2008) 8.69

Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev (2006) 8.26

MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene (2007) 4.46

MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease. Cancer Prev Res (Phila) (2009) 3.55

BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst (2003) 3.37

ATM mutations in patients with hereditary pancreatic cancer. Cancer Discov (2011) 3.27

Five years of prospective screening of high-risk individuals from families with familial pancreatic cancer. Gut (2009) 3.24

Frequent detection of pancreatic lesions in asymptomatic high-risk individuals. Gastroenterology (2012) 2.69

Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis. World J Surg (2009) 2.31

Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer. Transl Oncol (2010) 2.03

MicroRNA miR-155 is a biomarker of early pancreatic neoplasia. Cancer Biol Ther (2009) 2.01

PALB2 mutations in European familial pancreatic cancer families. Clin Genet (2010) 1.99

MicroRNA alterations of pancreatic intraepithelial neoplasias. Clin Cancer Res (2011) 1.97

MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions. Clin Chem (2010) 1.95

The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer. Gut (2009) 1.91

Analysis of microRNAs in pancreatic fine-needle aspirates can classify benign and malignant tissues. Clin Chem (2008) 1.87

Combination of plasma microRNAs with serum CA19-9 for early detection of pancreatic cancer. Int J Cancer (2011) 1.68

Advances in counselling and surveillance of patients at risk for pancreatic cancer. Gut (2007) 1.68

Combined serum CA19-9 and miR-27a-3p in peripheral blood mononuclear cells to diagnose pancreatic cancer. Cancer Prev Res (Phila) (2013) 1.66

Identification of serum microRNAs as novel non-invasive biomarkers for early detection of gastric cancer. PLoS One (2012) 1.66

Increased Prevalence of Precursor Lesions in Familial Pancreatic Cancer Patients. Clin Cancer Res (2009) 1.65

New biomarkers and targets in pancreatic cancer and their application to treatment. Nat Rev Gastroenterol Hepatol (2012) 1.57

Global microRNA expression profiling of microdissected tissues identifies miR-135b as a novel biomarker for pancreatic ductal adenocarcinoma. Int J Cancer (2011) 1.47

Clinical impact of circulating miR-221 in plasma of patients with pancreatic cancer. Br J Cancer (2013) 1.39

Familial and second primary pancreatic cancers: a nationwide epidemiologic study from Sweden. Int J Cancer (2003) 1.39

Diagnosis of pancreatic ductal adenocarcinoma and chronic pancreatitis by measurement of microRNA abundance in blood and tissue. PLoS One (2012) 1.36

Pancreatic intraepithelial neoplasia revisited and updated. Pancreatology (2008) 1.35

Aberrant MicroRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma. Pancreatology (2010) 1.31

Familial pancreatic cancer--current knowledge. Nat Rev Gastroenterol Hepatol (2012) 1.27

CDKN2A germline mutations in familial pancreatic cancer. Ann Surg (2002) 1.18

Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma. Int J Cancer (2012) 1.18

Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues. J Pathol (2012) 1.14

Tissue and serum microRNAs in the Kras(G12D) transgenic animal model and in patients with pancreatic cancer. PLoS One (2011) 1.12

MicroRNAs as diagnostic markers for pancreatic ductal adenocarcinoma and its precursor, pancreatic intraepithelial neoplasm. Cancer Genet (2013) 1.08

Prevalence of familial pancreatic cancer in Germany. Int J Cancer (2004) 1.02

Multiple small "imaging" branch-duct type intraductal papillary mucinous neoplasms (IPMNs) in familial pancreatic cancer: indicator for concomitant high grade pancreatic intraepithelial neoplasia? Fam Cancer (2013) 0.94

Diagnostic value of microRNA for pancreatic cancer: a meta-analysis. Arch Med Sci (2012) 0.93

Prevalence of BRCA2 and CDKN2a mutations in German familial pancreatic cancer families. Fam Cancer (2010) 0.88

MicroRNAs in pancreatic ductal adenocarcinoma: new diagnostic and therapeutic clues. Pancreatology (2008) 0.86