Published in J Clin Invest on May 01, 1989
ideR, An essential gene in mycobacterium tuberculosis: role of IdeR in iron-dependent gene expression, iron metabolism, and oxidative stress response. Infect Immun (2002) 4.54
Identification of Legionella pneumophila genes required for growth within and killing of human macrophages. Infect Immun (1993) 3.97
Mycobacterium avium subsp. paratuberculosis in Veterinary Medicine. Clin Microbiol Rev (2001) 3.58
Activation of macrophages for destruction of Francisella tularensis: identification of cytokines, effector cells, and effector molecules. Infect Immun (1992) 3.09
Legionella pneumophila replication vacuoles mature into acidic, endocytic organelles. J Exp Med (2000) 2.40
Exochelins of Mycobacterium tuberculosis remove iron from human iron-binding proteins and donate iron to mycobactins in the M. tuberculosis cell wall. J Exp Med (1996) 2.35
Iron acquisition by Mycobacterium tuberculosis: isolation and characterization of a family of iron-binding exochelins. Proc Natl Acad Sci U S A (1995) 2.17
Biosynthesis of nitric oxide activates iron regulatory factor in macrophages. EMBO J (1993) 1.83
Response of Chlamydia trachomatis serovar E to iron restriction in vitro and evidence for iron-regulated chlamydial proteins. Infect Immun (1997) 1.81
Regulation of transferrin receptor expression and ferritin content in human mononuclear phagocytes. Coordinate upregulation by iron transferrin and downregulation by interferon gamma. J Clin Invest (1993) 1.78
Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogens. J Clin Invest (1991) 1.68
Abrogation of gamma interferon-induced inhibition of Ehrlichia chaffeensis infection in human monocytes with iron-transferrin. Infect Immun (1994) 1.68
Iron in innate immunity: starve the invaders. Curr Opin Immunol (2009) 1.64
Intraphagocytic growth induces an antibiotic-resistant phenotype of Legionella pneumophila. Antimicrob Agents Chemother (1995) 1.63
Replicative Legionella pneumophila lung infection in intratracheally inoculated A/J mice. A murine model of human Legionnaires' disease. Am J Pathol (1994) 1.63
Identification of fur, aconitase, and other proteins expressed by Mycobacterium tuberculosis under conditions of low and high concentrations of iron by combined two-dimensional gel electrophoresis and mass spectrometry. Infect Immun (1999) 1.59
Chloroquine induces human macrophage killing of Histoplasma capsulatum by limiting the availability of intracellular iron and is therapeutic in a murine model of histoplasmosis. J Clin Invest (1994) 1.56
Iron limitation and the gamma interferon-mediated antihistoplasma state of murine macrophages. Infect Immun (1991) 1.50
Gallium disrupts iron metabolism of mycobacteria residing within human macrophages. Infect Immun (2000) 1.49
L-arginine-dependent killing of intracellular Ehrlichia risticii by macrophages treated with gamma interferon. Infect Immun (1992) 1.46
Legionella pneumophila feoAB promotes ferrous iron uptake and intracellular infection. Infect Immun (2002) 1.42
Legionella pneumophila mutants that are defective for iron acquisition and assimilation and intracellular infection. Infect Immun (1996) 1.40
In vivo regulation of replicative Legionella pneumophila lung infection by endogenous tumor necrosis factor alpha and nitric oxide. Infect Immun (1995) 1.36
Ehrlichia chaffeensis inclusions are early endosomes which selectively accumulate transferrin receptor. Infect Immun (1997) 1.35
Iron metabolism and the innate immune response to infection. Microbes Infect (2011) 1.32
Iron homeostasis in host defence and inflammation. Nat Rev Immunol (2015) 1.28
An iron- and fur-repressed Legionella pneumophila gene that promotes intracellular infection and encodes a protein with similarity to the Escherichia coli aerobactin synthetases. Infect Immun (1997) 1.27
Role of transferrin, transferrin receptors, and iron in macrophage listericidal activity. J Exp Med (1991) 1.27
Inhibition of Legionella pneumophila growth by gamma interferon in permissive A/J mouse macrophages: role of reactive oxygen species, nitric oxide, tryptophan, and iron(III). Infect Immun (1994) 1.27
Role of iron in Nramp1-mediated inhibition of mycobacterial growth. Infect Immun (1999) 1.24
The siderophore 2,3-dihydroxybenzoic acid is not required for virulence of Brucella abortus in BALB/c mice. Infect Immun (1999) 1.24
Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection. J Exp Med (2013) 1.22
Ehrlichia chaffeensis and E. sennetsu, but not the human granulocytic ehrlichiosis agent, colocalize with transferrin receptor and up-regulate transferrin receptor mRNA by activating iron-responsive protein 1. Infect Immun (1999) 1.20
Tumor necrosis factor alpha (TNFalpha) promotes growth of virulent Mycobacterium tuberculosis in human monocytes iron-mediated growth suppression is correlated with decreased release of TNFalpha from iron-treated infected monocytes. J Clin Invest (1997) 1.20
The major iron-containing protein of Legionella pneumophila is an aconitase homologous with the human iron-responsive element-binding protein. J Bacteriol (1993) 1.18
Delayed translational silencing of ceruloplasmin transcript in gamma interferon-activated U937 monocytic cells: role of the 3' untranslated region. Mol Cell Biol (1999) 1.17
Acquisition of iron by Legionella pneumophila: role of iron reductase. Infect Immun (1991) 1.16
The secreted pyomelanin pigment of Legionella pneumophila confers ferric reductase activity. Infect Immun (2007) 1.16
Inhibition of Ehrlichia risticii infection in murine peritoneal macrophages by gamma interferon, a calcium ionophore, and concanavalin A. Infect Immun (1991) 1.14
Nitrogen monoxide-mediated control of ferritin synthesis: implications for macrophage iron homeostasis. Proc Natl Acad Sci U S A (2002) 1.14
The Legionella pneumophila iraAB locus is required for iron assimilation, intracellular infection, and virulence. Infect Immun (2000) 1.12
Metallomic analysis of macrophages infected with Histoplasma capsulatum reveals a fundamental role for zinc in host defenses. J Infect Dis (2010) 1.12
In vivo regulation of replicative Legionella pneumophila lung infection by endogenous interleukin-12. Infect Immun (1998) 1.11
A Legionella pneumophila gene that promotes hemin binding. Infect Immun (1996) 1.11
Upregulation of IFN-gamma receptor expression by proinflammatory cytokines influences IDO activation in epithelial cells. J Interferon Cytokine Res (2006) 1.09
Transient transgenic expression of gamma interferon promotes Legionella pneumophila clearance in immunocompetent hosts. Infect Immun (2001) 1.07
Discovery of a nonclassical siderophore, legiobactin, produced by strains of Legionella pneumophila. J Bacteriol (2000) 1.07
Definition of a lipopolysaccharide-responsive element in the 5'-flanking regions of MuRantes and crg-2. Mol Cell Biol (1994) 1.07
Comparative analysis of Legionella pneumophila and Legionella micdadei virulence traits. Infect Immun (1999) 1.06
Effector mechanisms responsible for gamma interferon-mediated host resistance to Legionella pneumophila lung infection: the role of endogenous nitric oxide differs in susceptible and resistant murine hosts. Infect Immun (1996) 1.06
Interferon-gamma-activated primary enterocytes inhibit Toxoplasma gondii replication: a role for intracellular iron. Immunology (1998) 1.05
Macrophage permissiveness for Legionella pneumophila growth modulated by iron. Infect Immun (1994) 1.04
Gamma interferon protects endothelial cells from damage by Candida albicans by inhibiting endothelial cell phagocytosis. Infect Immun (1996) 1.03
Ferric reduction is a potential iron acquisition mechanism for Histoplasma capsulatum. Infect Immun (1999) 1.02
Nitrite production by macrophages derived from BCG-resistant and -susceptible congenic mouse strains in response to IFN-gamma and infection with BCG. Immunology (1994) 1.02
Maturation of the Legionella pneumophila-containing phagosome into a phagolysosome within gamma interferon-activated macrophages. Infect Immun (2005) 1.02
Influence of iron status on risk of maternal or neonatal infection and on neonatal mortality with an emphasis on developing countries. Nutr Rev (2013) 1.00
Mechanisms involved in uptake of Bordetella bronchiseptica by mouse dendritic cells. Infect Immun (1994) 1.00
The cytochrome c maturation locus of Legionella pneumophila promotes iron assimilation and intracellular infection and contains a strain-specific insertion sequence element. Infect Immun (2002) 0.99
Influence of iron-limited continuous culture on physiology and virulence of Legionella pneumophila. Infect Immun (1995) 0.99
Persistence of the bacterial pathogen Granulibacter bethesdensis in chronic granulomatous disease monocytes and macrophages lacking a functional NADPH oxidase. J Immunol (2013) 0.98
New challenges in studying nutrition-disease interactions in the developing world. J Clin Invest (2008) 0.98
Modulation of iron homeostasis in macrophages by bacterial intracellular pathogens. BMC Microbiol (2010) 0.97
Immunomodulatory role of endogenous interleukin-18 in gamma interferon-mediated resolution of replicative Legionella pneumophila lung infection. Infect Immun (2000) 0.95
Suppression by human recombinant gamma interferon of in vitro macrophage nonopsonic and opsonic phagocytosis and killing. Infect Immun (1991) 0.92
Iron sequestration by macrophages decreases the potential for extracellular hydroxyl radical formation. J Clin Invest (1993) 0.92
Inhibitory effect of deferoxamine or macrophage activation on transformation of Paracoccidioides brasiliensis conidia ingested by macrophages: reversal by holotransferrin. Infect Immun (1994) 0.92
Gamma interferon-activated human macrophages and Toxoplasma gondii, Chlamydia psittaci, and Leishmania donovani: antimicrobial role of limiting intracellular iron. Infect Immun (1991) 0.92
Coxiella burnetii infection increases transferrin receptors on J774A. 1 cells. Infect Immun (1999) 0.91
The nature of extracellular iron influences iron acquisition by Mycobacterium tuberculosis residing within human macrophages. Infect Immun (2004) 0.90
Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication. Infect Immun (2013) 0.89
Evidence for a role for interleukin-17, Th17 cells and iron homeostasis in protective immunity against tuberculosis in cynomolgus macaques. PLoS One (2014) 0.88
Differential morphologic and metabolic alterations in permissive versus nonpermissive murine macrophages infected with Legionella pneumophila. Infect Immun (1992) 0.88
Iron and infection in hemodialysis patients. Semin Dial (2013) 0.88
The role of cytokines and chemokines in Histoplasma capsulatum infection. Cytokine (2011) 0.87
Intracellular growth inhibition of Histoplasma capsulatum induced in murine macrophages by recombinant gamma interferon is not due to a limitation of the supply of methionine or cysteine to the fungus. Infect Immun (1992) 0.87
The Role of the Immune Response in Chlamydia trachomatis Infection of the Male Genital Tract: A Double-Edged Sword. Front Immunol (2014) 0.85
Prooxidant activity of transferrin and lactoferrin. J Exp Med (1990) 0.85
Difference in Legionella pneumophila growth permissiveness between J774.1 murine macrophage-like JA-4 cells and lipopolysaccharide (LPS)-resistant mutant cells, LPS1916, after stimulation with LPS. Infect Immun (1994) 0.85
Infection with Mycobacterium avium differentially regulates the expression of iron transport protein mRNA in murine peritoneal macrophages. Infect Immun (2001) 0.85
The alternative translational profile that underlies the immune-evasive state of persistence in Chlamydiaceae exploits differential tryptophan contents of the protein repertoire. Microbiol Mol Biol Rev (2012) 0.85
Phenylalanine hydroxylase from Legionella pneumophila is a thermostable enzyme with a major functional role in pyomelanin synthesis. PLoS One (2012) 0.84
Limited role for iron regulation in Coxiella burnetii pathogenesis. Infect Immun (2008) 0.84
Macrophage activation for intracellular killing as induced by a Ca2+ ionophore. Dependence on L-arginine-derived nitrogen oxidation products. Biochem J (1992) 0.82
Innate defects of the IL-12/IFN-γ axis in susceptibility to infections by mycobacteria and salmonella. J Interferon Cytokine Res (2013) 0.81
Gamma interferon confers resistance to infection with Staphylococcus aureus in human vascular endothelial cells by cooperative proinflammatory and enhanced intrinsic antibacterial activities. Infect Immun (2007) 0.81
Histoplasma capsulatum surmounts obstacles to intracellular pathogenesis. FEBS J (2015) 0.79
Metal acquisition and virulence in Brucella. Anim Health Res Rev (2012) 0.79
Nitric oxide-mediated intracellular growth restriction of pathogenic Rhodococcus equi can be prevented by iron. Infect Immun (2011) 0.78
2-Deoxy-D-glucose inhibits intracellular multiplication and promotes intracellular killing of Legionella pneumophila in A/J mouse macrophages. Infect Immun (1994) 0.78
Chapter 2: Use of iron to treat anemia in CKD. Kidney Int Suppl (2011) (2012) 0.77
Bafilomycin A1 and intracellular multiplication of Legionella pneumophila. Antimicrob Agents Chemother (1997) 0.77
Subversion of Cell-Autonomous Immunity and Cell Migration by Legionella pneumophila Effectors. Front Immunol (2015) 0.76
The exochelins of pathogenic mycobacteria: unique, highly potent, lipid- and water-soluble hexadentate iron chelators with multiple potential therapeutic uses. Antioxid Redox Signal (2014) 0.76
Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J Clin Invest (1980) 12.41
Primary isolation media for Legionnaires disease bacterium. J Clin Microbiol (1978) 11.86
Response of cultured macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes. J Exp Med (1971) 11.44
Interaction of L cells and Chlamydia psittaci: entry of the parasite and host responses to its development. J Bacteriol (1972) 11.22
The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J Exp Med (1983) 8.82
The interaction between Toxoplasma gondii and mammalian cells. II. The absence of lysosomal fusion with phagocytic vacuoles containing living parasites. J Exp Med (1972) 8.66
pH and the recycling of transferrin during receptor-mediated endocytosis. Proc Natl Acad Sci U S A (1983) 8.41
Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J Exp Med (1983) 7.65
Tumor-promoting phorbol esters stimulate C3b and C3b' receptor-mediated phagocytosis in cultured human monocytes. J Exp Med (1982) 7.10
Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway. Cell (1984) 6.50
Active oxygen species and the functions of phagocytic leukocytes. Annu Rev Biochem (1980) 5.86
Activation of macrophages in vivo and in vitro. Correlation between hydrogen peroxide release and killing of Trypanosoma cruzi. J Exp Med (1979) 5.22
Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol (1984) 4.88
Trypanosoma cruzi: mechanism of entry and intracellular fate in mammalian cells. J Exp Med (1976) 4.36
Induction of tryptophan catabolism is the mechanism for gamma-interferon-mediated inhibition of intracellular Chlamydia psittaci replication in T24 cells. Infect Immun (1986) 4.34
Activated human monocytes inhibit the intracellular multiplication of Legionnaires' disease bacteria. J Exp Med (1981) 4.08
Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes. J Exp Med (1983) 3.96
Phagocytosis of Legionella pneumophila is mediated by human monocyte complement receptors. J Exp Med (1987) 3.78
Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone. J Clin Invest (1984) 3.59
Multiplication of a human parasite (Leishmania donovani) in phagolysosomes of hamster macrophages in vitro. Science (1976) 3.55
Activation of human macrophages. Comparison of other cytokines with interferon-gamma. J Exp Med (1984) 3.02
Fusion of host cell secondary lysosomes with the parasitophorous vacuoles of Leishmania mexicana-infected macrophages. J Protozool (1975) 2.93
Interferon-gamma-activated human monocytes inhibit the intracellular multiplication of Legionella pneumophila. J Immunol (1986) 2.62
Cell-mediated immunity in Legionnaires' disease. J Clin Invest (1983) 2.30
Low molecular weight intracellular iron transport compounds. Blood (1977) 2.02
The pathology of the Legionella pneumonias. A review of 74 cases and the literature. Hum Pathol (1981) 1.94
IFN-gamma-activated human alveolar macrophages inhibit the intracellular multiplication of Legionella pneumophila. J Immunol (1988) 1.87
Dissociation of phagocytosis from stimulation of the oxidative metabolic burst in macrophages. J Exp Med (1984) 1.85
Absence of siderophore activity in Legionella species grown in iron-deficient media. J Bacteriol (1983) 1.77
Studies of in vitro infection by Trypanosoma cruzi. I. Ultrastructural studies on the invasion of macrophages and L-cells. Am J Trop Med Hyg (1975) 1.74
Interferon-gamma suppresses the growth of Toxoplasma gondii in human fibroblasts through starvation for tryptophan. Mol Biochem Parasitol (1986) 1.68
Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures. J Immunol (1987) 1.65
Susceptibility of Legionella pneumophila to oxygen-dependent microbicidal systems. J Immunol (1982) 1.61
Ligated complement receptors do not activate the arachidonic acid cascade in resident peritoneal macrophages. J Exp Med (1985) 1.60
Complete inhibition of transferrin recycling by monensin in K562 cells. J Biol Chem (1984) 1.40
Plasmodium falciparum: inhibition of in vitro growth by desferrioxamine. Am J Trop Med Hyg (1982) 1.39
Interaction of primate alveolar macrophages and Legionella pneumophila. J Clin Invest (1984) 1.29
Expression of the transferrin receptor on murine peritoneal macrophages is modulated by in vitro treatment with interferon gamma. Cell Immunol (1984) 1.25
Chelate mediated transfer of iron from transferrin to desferrioxamine. Br J Haematol (1976) 1.23
Role of iron in intracellular growth of Trypanosoma cruzi. Infect Immun (1984) 1.23
Deferoxamine inhibition of malaria is independent of host iron status. J Exp Med (1988) 1.17
The site of action of desferrioxamine. Br J Haematol (1971) 1.16
Expression of the transferrin receptor in murine peritoneal macrophages is modulated in the different stages of activation. J Immunol (1984) 1.16
Expression of the transferrin receptor gene during the process of mononuclear phagocyte maturation. J Immunol (1986) 1.05
In vitro activation of the antibacterial activity of human pulmonary macrophages by recombinant gamma interferon. J Infect Dis (1987) 1.05
Expression of transferrin receptors and intracellular ferritin during terminal differentiation of human monocytes. Blut (1984) 1.02
Mobilisation of iron from peritoneal rat macrophages by desferrioxamine. Scand J Haematol (1981) 0.85
Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J Clin Invest (1980) 12.41
The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J Exp Med (1983) 8.82
Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J Exp Med (1983) 7.65
Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J Exp Med (1995) 6.62
Influence of the Escherichia coli capsule on complement fixation and on phagocytosis and killing by human phagocytes. J Clin Invest (1980) 6.61
Phagocytosis of Mycobacterium tuberculosis is mediated by human monocyte complement receptors and complement component C3. J Immunol (1990) 5.39
Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol (1984) 4.88
Activated human monocytes inhibit the intracellular multiplication of Legionnaires' disease bacteria. J Exp Med (1981) 4.08
Phagocytosis of the Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: engulfment within a pseudopod coil. Cell (1984) 4.00
Immunization with extracellular proteins of Mycobacterium tuberculosis induces cell-mediated immune responses and substantial protective immunity in a guinea pig model of pulmonary tuberculosis. Infect Immun (1992) 3.85
Intracellular multiplication of Legionnaires' disease bacteria (Legionella pneumophila) in human monocytes is reversibly inhibited by erythromycin and rifampin. J Clin Invest (1983) 3.79
Phagocytosis of Legionella pneumophila is mediated by human monocyte complement receptors. J Exp Med (1987) 3.78
Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone. J Clin Invest (1984) 3.59
The cutaneous infiltrates of leprosy: cellular characteristics and the predominant T-cell phenotypes. N Engl J Med (1982) 3.52
Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages. Proc Natl Acad Sci U S A (1992) 3.32
Interaction of the Legionnaires' disease bacterium (Legionella pneumophila) with human phagocytes. I. L. pneumophila resists killing by polymorphonuclear leukocytes, antibody, and complement. J Exp Med (1981) 3.27
Phagocytosis of microorganisms. Rev Infect Dis (1982) 2.68
Interferon-gamma-activated human monocytes inhibit the intracellular multiplication of Legionella pneumophila. J Immunol (1986) 2.62
Identification of macrophage and stress-induced proteins of Mycobacterium tuberculosis. J Clin Invest (1995) 2.43
Novel insights into the genetics, biochemistry, and immunocytochemistry of the 30-kilodalton major extracellular protein of Mycobacterium tuberculosis. Infect Immun (1996) 2.43
The Philippine cynomolgus monkey (Macaca fasicularis) provides a new nonhuman primate model of tuberculosis that resembles human disease. Nat Med (1996) 2.40
The Mycobacterium tuberculosis phagosome interacts with early endosomes and is accessible to exogenously administered transferrin. J Exp Med (1996) 2.37
Isolation and characterization of the cytoplasmic and outer membranes of the Legionnaires' disease bacterium (Legionella pneumophila). J Exp Med (1985) 2.37
Exochelins of Mycobacterium tuberculosis remove iron from human iron-binding proteins and donate iron to mycobactins in the M. tuberculosis cell wall. J Exp Med (1996) 2.35
Cell-mediated immunity in Legionnaires' disease. J Clin Invest (1983) 2.30
Glutamine synthetase of Mycobacterium tuberculosis: extracellular release and characterization of its enzymatic activity. Proc Natl Acad Sci U S A (1994) 2.26
Iron acquisition by Mycobacterium tuberculosis: isolation and characterization of a family of iron-binding exochelins. Proc Natl Acad Sci U S A (1995) 2.17
Vaccination with the major secretory protein of Legionella pneumophila induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease. J Exp Med (1989) 1.91
Purification of Legionella pneumophila major outer membrane protein and demonstration that it is a porin. J Bacteriol (1985) 1.91
IFN-gamma-activated human alveolar macrophages inhibit the intracellular multiplication of Legionella pneumophila. J Immunol (1988) 1.87
Complement component C3 fixes selectively to the major outer membrane protein (MOMP) of Legionella pneumophila and mediates phagocytosis of liposome-MOMP complexes by human monocytes. J Exp Med (1990) 1.79
Regulation of transferrin receptor expression and ferritin content in human mononuclear phagocytes. Coordinate upregulation by iron transferrin and downregulation by interferon gamma. J Clin Invest (1993) 1.78
Defective production of monocyte-activating cytokines in lepromatous leprosy. J Exp Med (1984) 1.74
Deviant expression of Rab5 on phagosomes containing the intracellular pathogens Mycobacterium tuberculosis and Legionella pneumophila is associated with altered phagosomal fate. Infect Immun (2000) 1.71
The HL-60 model for the interaction of human macrophages with the Legionnaires' disease bacterium. J Immunol (1990) 1.70
Chloroquine inhibits the intracellular multiplication of Legionella pneumophila by limiting the availability of iron. A potential new mechanism for the therapeutic effect of chloroquine against intracellular pathogens. J Clin Invest (1991) 1.68
Membrane sorting during phagocytosis: selective exclusion of major histocompatibility complex molecules but not complement receptor CR3 during conventional and coiling phagocytosis. J Exp Med (1992) 1.67
Phagocytosis of leprosy bacilli is mediated by complement receptors CR1 and CR3 on human monocytes and complement component C3 in serum. J Clin Invest (1990) 1.66
Treatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-L-glutamate/glutamine cell wall structure, and bacterial replication. Proc Natl Acad Sci U S A (2000) 1.65
Identification of fur, aconitase, and other proteins expressed by Mycobacterium tuberculosis under conditions of low and high concentrations of iron by combined two-dimensional gel electrophoresis and mass spectrometry. Infect Immun (1999) 1.59
Purification, characterization, and genetic analysis of Mycobacterium tuberculosis urease, a potentially critical determinant of host-pathogen interaction. J Bacteriol (1995) 1.43
High-level heterologous expression and secretion in rapidly growing nonpathogenic mycobacteria of four major Mycobacterium tuberculosis extracellular proteins considered to be leading vaccine candidates and drug targets. Infect Immun (1997) 1.42
Major cytoplasmic membrane protein of Legionella pneumophila, a genus common antigen and member of the hsp 60 family of heat shock proteins, induces protective immunity in a guinea pig model of Legionnaires' disease. J Clin Invest (1993) 1.41
An immunoprotective molecule, the major secretory protein of Legionella pneumophila, is not a virulence factor in a guinea pig model of Legionnaires' disease. J Clin Invest (1990) 1.41
An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase. J Mol Biol (2001) 1.40
Outbreaks of waterborne disease in the United States, 1974. J Infect Dis (1976) 1.38
Expression and efficient export of enzymatically active Mycobacterium tuberculosis glutamine synthetase in Mycobacterium smegmatis and evidence that the information for export is contained within the protein. J Biol Chem (1997) 1.36
Hypoexpression of major histocompatibility complex molecules on Legionella pneumophila phagosomes and phagolysosomes. Infect Immun (1993) 1.35
Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7. Infect Immun (2000) 1.31
Phenolic glycolipid-1 of Mycobacterium leprae binds complement component C3 in serum and mediates phagocytosis by human monocytes. J Exp Med (1991) 1.27
Identification of iron-regulated proteins of Mycobacterium tuberculosis and cloning of tandem genes encoding a low iron-induced protein and a metal transporting ATPase with similarities to two-component metal transport systems. Microb Pathog (1998) 1.22
A role for natural antibody in the pathogenesis of leprosy: antibody in nonimmune serum mediates C3 fixation to the Mycobacterium leprae surface and hence phagocytosis by human mononuclear phagocytes. Infect Immun (1994) 1.21
The major iron-containing protein of Legionella pneumophila is an aconitase homologous with the human iron-responsive element-binding protein. J Bacteriol (1993) 1.18
Food-borne botulism in the United States, 1970-1975. J Infect Dis (1977) 1.10
T-cell epitope mapping of the three most abundant extracellular proteins of Mycobacterium tuberculosis in outbred guinea pigs. Infect Immun (1999) 1.08
A live avirulent mutant Legionella pneumophila vaccine induces protective immunity against lethal aerosol challenge. J Clin Invest (1989) 1.07
Characterization of exochelins of Mycobacterium avium: evidence for saturated and unsaturated and for acid and ester forms. J Bacteriol (1996) 1.03
Effect of recombinant interferon-gamma on hydrogen peroxide-releasing capacity of monocyte-derived macrophages from patients with lepromatous leprosy. J Immunol (1986) 1.01
A large outbreak of foodborne salmonellosis on the Navajo Nation Indian Reservation, epidemiology and secondary transmission. Am J Public Health (1977) 1.00
Characterization of exochelins of the Mycobacterium bovis type strain and BCG substrains. Infect Immun (1999) 0.99
Laboratory diagnosis of botulism complicated by pyridostigmine treatment of the patient. A method for selectively removing interfering substances from clinical specimens. Am J Clin Pathol (1976) 0.98
Vaccination with Legionella pneumophila membranes induces cell-mediated and protective immunity in a guinea pig model of Legionnaires' disease. Protective immunity independent of the major secretory protein of Legionella pneumophila. J Clin Invest (1991) 0.95
Foodborne disease outbreaks of chemical etiology in the United States, 1970-1974. Am J Epidemiol (1977) 0.94
Lipophilic siderophores of Mycobacterium tuberculosis prevent cardiac reperfusion injury. Proc Natl Acad Sci U S A (1998) 0.90
An exochelin of Mycobacterium tuberculosis reversibly arrests growth of human vascular smooth muscle cells in vitro. J Biol Chem (2000) 0.89
The roles of the Fc and C3 receptors in the phagocytosis and killing of bacteria by human phagocytes. J Reticuloendothel Soc (1980) 0.88
Legionella pneumophila invasion of mononuclear phagocytes. Curr Top Microbiol Immunol (1996) 0.87
A novel iron chelator in combination with a P-selectin antagonist prevents ischemia/reperfusion injury in a rat liver model. Transplantation (2001) 0.85
Aberrantly low transferrin receptor expression on human monocytes is associated with nonpermissiveness for Legionella pneumophila growth. J Infect Dis (2000) 0.84
Specific diagnosis of foodborne disease. Gastroenterology (1977) 0.84
Desferri-exochelin induces death by apoptosis in human breast cancer cells but does not kill normal breast cells. Breast Cancer Res Treat (2001) 0.83
Type A botulism from commercially canned beef stew. South Med J (1977) 0.83
Symbiotic interactions between Legionella pneumophila and human leukocytes. Int Rev Cytol Suppl (1983) 0.83
An iron-binding exochelin prevents restenosis due to coronary artery balloon injury in a porcine model. Circulation (2001) 0.82
Nursery outbreak of peritonitis with pneumoperitoneum probably caused by thermometer-induced rectal perforation. Am J Epidemiol (1976) 0.80
Interferon-gamma and antibiotics fail to act synergistically to kill Legionella pneumophila in human monocytes. J Interferon Res (1988) 0.78
Phagosome-lysosome fusion. Biochem Soc Trans (1986) 0.77
A continuing common-source outbreak of botulism in a family. Lancet (1975) 0.75
From the center of disease control. Outbreaks of food-borne disease in the United States, 1974. J Infect Dis (1976) 0.75