Published in Sci Rep on June 26, 2014
The impact of recombination on human mutation load and disease. Philos Trans R Soc Lond B Biol Sci (2017) 0.75
The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res (2010) 97.51
Fast gapped-read alignment with Bowtie 2. Nat Methods (2012) 83.79
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res (2010) 43.51
Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science (2004) 21.65
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature (1983) 11.57
Genetic heterogeneity in human disease. Cell (2010) 10.67
Schizophrenia: a common disease caused by multiple rare alleles. Br J Psychiatry (2007) 7.00
Zinc finger proteins: new insights into structural and functional diversity. Curr Opin Struct Biol (2001) 4.92
Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13. Oncogene (1995) 2.91
What would you do if you could sequence everything? Nat Biotechnol (2008) 2.89
Unexpected allelic heterogeneity and spectrum of mutations in Fowler syndrome revealed by next-generation exome sequencing. Hum Mutat (2010) 1.76
Mechanisms underlying losses of heterozygosity in human colorectal cancers. Proc Natl Acad Sci U S A (2001) 1.68
Study of matrix metalloproteinases and their inhibitors in breast cancer. Br J Cancer (2007) 1.63
Idiographica: a general-purpose web application to build idiograms on-demand for human, mouse and rat. Bioinformatics (2007) 1.60
Functional modules, mutational load and human genetic disease. Trends Genet (2010) 1.45
High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss. Am J Pathol (2001) 1.36
Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation, and leads to apoptosis in malignant gliomas. Lab Invest (1998) 1.26
Loss of heterozygosity mapping at chromosome arm 16q in 712 breast tumors reveals factors that influence delineation of candidate regions. Cancer Res (2001) 1.23
Cancer metastasis. Br Med Bull (1991) 1.14
P-cadherin expression in breast carcinoma indicates poor survival. Cancer (1999) 1.09
Homologous recombination as a mechanism of carcinogenesis. Biochim Biophys Acta (2001) 0.96
Amentoflavone inhibits experimental tumor metastasis through a regulatory mechanism involving MMP-2, MMP-9, prolyl hydroxylase, lysyl oxidase, VEGF, ERK-1, ERK-2, STAT-1, NM23 and cytokines in lung tissues of C57BL/6 mice. Immunopharmacol Immunotoxicol (2008) 0.95
Neurobeachin (NBEA) is a target of recurrent interstitial deletions at 13q13 in patients with MGUS and multiple myeloma. Exp Hematol (2009) 0.93
Bradykinin stimulates the ERK-->Elk-1-->Fos/AP-1 pathway in mesangial cells. Am J Physiol (1998) 0.93
Cadherins as predictive markers of nodal metastasis in breast cancer. Mod Pathol (2001) 0.88
Loss of heterozygosity accumulation in primary breast carcinomas and additionally in corresponding distant metastases is associated with poor outcome. Clin Cancer Res (1999) 0.87
Protein expression analysis of ALCAM and CEACAM6 in breast cancer metastases reveals significantly increased ALCAM expression in metastases of the skin. J Clin Pathol (2011) 0.85
Clinicopathological significance of CEACAM1 gene expression in breast cancer. Chin J Physiol (2011) 0.83
Expression of the adhesion molecule CEACAM1 (CD66a, BGP, C-CAM) in breast cancer is associated with the expression of the tumor-suppressor genes Rb, Rb2, and p27. Virchows Arch (2002) 0.83
[Human carcinoembryonic antigen family proteins, structure and function]. Postepy Hig Med Dosw (Online) (2012) 0.77