Published in AAPS PharmSciTech on June 27, 2014
Drug delivery to the nail following topical application. Int J Pharm (2002) 1.35
Ciclopirox: recent nonclinical and clinical data relevant to its use as a topical antimycotic agent. Drugs (2010) 1.33
In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity. Br J Dermatol (2003) 1.18
Effect of a novel penetration enhancer on the ungual permeation of two antifungal agents. J Pharm Pharmacol (2010) 1.17
Chemical method to enhance transungual transport and iontophoresis efficiency. Int J Pharm (2008) 1.16
Nail swelling as a pre-formulation screen for the selection and optimisation of ungual penetration enhancers. Pharm Res (2007) 1.14
Drug permeation through the three layers of the human nail plate. J Pharm Pharmacol (1999) 0.98
Enhancing the nail permeability of topically applied drugs. Expert Opin Drug Deliv (2008) 0.91
Ciclopirox delivery into the human nail plate. J Pharm Sci (2004) 0.90
Ungual and transungual drug delivery. Drug Dev Ind Pharm (2011) 0.89
An investigation into keratinolytic enzymes to enhance ungual drug delivery. Int J Pharm (2006) 0.88
Hydration of nail plate: a novel screening model for transungual drug permeation enhancers. Int J Pharm (2012) 0.88
Evaluation of microdilution and disk diffusion methods for antifungal susceptibility testing of dermatophytes. Med Mycol (2007) 0.87
Iontophoretically enhanced ciclopirox delivery into and across human nail plate. J Pharm Sci (2009) 0.86
Investigation of nail permeation enhancement by chemical modification using water as a probe. J Pharm Sci (2002) 0.85
TranScreen-N: Method for rapid screening of trans-ungual drug delivery enhancers. J Pharm Sci (2009) 0.85
Ungual and trans-ungual iontophoretic delivery of terbinafine for the treatment of onychomycosis. J Pharm Sci (2009) 0.85
Histological structure of human nail as studied by synchrotron X-ray microdiffraction. Cell Mol Biol (Noisy-le-grand) (2000) 0.84
Alteration of the diffusional barrier property of the nail leads to greater terbinafine drug loading and permeation. Int J Pharm (2009) 0.83
Comparison between the standardized clinical and laboratory standards institute M38-A2 method and a 2,3-Bis(2-Methoxy-4-Nitro-5-[(Sulphenylamino)Carbonyl]-2H-tetrazolium hydroxide- based method for testing antifungal susceptibility of dermatophytes. J Clin Microbiol (2008) 0.82
Penetration of lucifer yellow into human skin: a lateral diffusion channel in the stratum corneum. J Histochem Cytochem (1993) 0.82
Validation of bovine hoof slices as a model for infected human toenails: in vitro ciclopirox transungual permeation. Br J Dermatol (2011) 0.82
Enhancing effect of N-acetyl-l-cysteine or 2-mercaptoethanol on the in vitro permeation of 5-fluorouracil or tolnaftate through the human nail plate. Chem Pharm Bull (Tokyo) (1998) 0.81
Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria. Int J Dermatol (2003) 0.81
Permeation of ciclopirox across porcine hoof membrane: effect of pressure sensitive adhesives and vehicles. Eur J Pharm Sci (2003) 0.81
Quantification of ciclopirox by high-performance liquid chromatography after pre-column derivatization. An example of efficient clean-up using silica-bonded cyano phases. J Chromatogr (1985) 0.79
A study on the effect of inorganic salts in transungual drug delivery of terbinafine. J Pharm Pharmacol (2009) 0.79
Photothermal imaging in 3D surface analysis of membrane drug delivery. Eur J Pharm Biopharm (2009) 0.78
Lateral diffusion of ibuprofen in human skin during permeation studies. Skin Pharmacol Physiol (2004) 0.78
Effect of polyethylene glycols on the trans-ungual delivery of terbinafine. Curr Drug Deliv (2010) 0.77
An ex vivo toe model used to assess applicators for the iontophoretic ungual delivery of terbinafine. Pharm Res (2009) 0.77
The effect of keratolytic agents on the permeability of three imidazole antimycotic drugs through the human nail. Drug Dev Ind Pharm (1998) 0.77
A preformulation strategy for the selection of penetration enhancers for a transungual formulation. AAPS PharmSciTech (2013) 0.77
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med (2004) 3.92
Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nat Genet (2011) 2.32
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol (2014) 1.95
Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation. Development (2004) 1.88
On the evolutionary history, population genetics and diversity among isolates of Salmonella Enteritidis PFGE pattern JEGX01.0004. PLoS One (2013) 1.69
High resolution clustering of Salmonella enterica serovar Montevideo strains using a next-generation sequencing approach. BMC Genomics (2012) 1.68
Quantitative trait loci influence renal disease progression in a mouse model of Alport syndrome. Am J Pathol (2002) 1.67
Subcapsular renal haematoma after holmium:yttrium-aluminum-garnet laser ureterolithotripsy. BJU Int (2011) 1.55
Role of the pituitary tumor transforming gene 1 in the progression of hepatocellular carcinoma. Cancer Biol Ther (2011) 1.44
Transcriptional induction of slit diaphragm genes by Lmx1b is required in podocyte differentiation. J Clin Invest (2002) 1.39
Delineating an oncostatin M-activated STAT3 signaling pathway that coordinates the expression of genes involved in cell cycle regulation and extracellular matrix deposition of MCF-7 cells. Oncogene (2003) 1.33
Assessment of association of rs2200733 on chromosome 4q25 with atrial fibrillation and ischemic stroke in a Chinese Han population. Hum Genet (2009) 1.25
Baseline survey of the anatomical microbial ecology of an important food plant: Solanum lycopersicum (tomato). BMC Microbiol (2013) 1.21
N'-(2-Methoxy-benzyl-idene)nicotinohydrazide. Acta Crystallogr Sect E Struct Rep Online (2010) 1.19
Prognostic significance of AEG-1 expression in colorectal carcinoma. Int J Colorectal Dis (2010) 1.18
Comparative genomic analysis and virulence differences in closely related salmonella enterica serotype heidelberg isolates from humans, retail meats, and animals. Genome Biol Evol (2014) 1.16
Draft genome sequences of 21 Salmonella enterica serovar enteritidis strains. J Bacteriol (2012) 1.15
Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules. Proc Natl Acad Sci U S A (2011) 1.14
A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development. J Am Soc Nephrol (2002) 1.06
Analysis of the evolutionary forces shaping mitochondrial genomes of a Neotropical malaria vector complex. Mol Phylogenet Evol (2011) 1.06
Decreasing the spectral radius of a graph by link removals. Phys Rev E Stat Nonlin Soft Matter Phys (2011) 1.05
Adsorption of Pb(II) on activated carbon prepared from Polygonum orientale Linn.: kinetics, isotherms, pH, and ionic strength studies. Bioresour Technol (2010) 1.04
Minor allele C of chromosome 1p32 single nucleotide polymorphism rs11206510 confers risk of ischemic stroke in the Chinese Han population. Stroke (2010) 1.03
Synuclein gamma inhibits the mitotic checkpoint function and promotes chromosomal instability of breast cancer cells. Breast Cancer Res Treat (2005) 1.02
Over-expression of LAPTM4B is associated with poor prognosis and chemotherapy resistance in stages III and IV epithelial ovarian cancer. J Surg Oncol (2011) 1.01
LAPTM4B overexpression is a novel predictor of epithelial ovarian carcinoma metastasis. Int J Cancer (2010) 1.00
Molecular Phylogeny of Neotropical Anopheles (Nyssorhynchus) Albitarsis Species Complex (Diptera: Culicidae). Ann Entomol Soc Am (2005) 0.99
Two-order targeted brain tumor imaging by using an optical/paramagnetic nanoprobe across the blood brain barrier. ACS Nano (2011) 0.99
Ribosomal DNA ITS2 sequences differentiate six species in the Anopheles crucians complex (Diptera: Culicidae). J Med Entomol (2004) 0.99
Distribution and larval habitat characteristics of Anopheles Hyrcanus group and related mosquito species (Diptera: Culicidae) in South Korea. J Vector Ecol (2006) 0.99
Genome sequences of five Salmonella enterica serovar Heidelberg isolates associated with a 2011 multistate outbreak in the United States. J Bacteriol (2012) 0.98
A polysaccharide from the fungi of Huaier exhibits anti-tumor potential and immunomodulatory effects. Carbohydr Polym (2012) 0.97
Controllable growth and transfer of monolayer MoS2 on Au foils and its potential application in hydrogen evolution reaction. ACS Nano (2014) 0.97
Synthesis and biological evaluation of novel dihydro-aryl/alkylsulfanyl-cyclohexylmethyl-oxopyrimidines (S-DACOs) as high active anti-HIV agents. Bioorg Med Chem Lett (2010) 0.97
MET amplification is not rare and predicts unfavorable clinical outcomes in patients with recurrent/metastatic gastric cancer after chemotherapy. Cancer (2013) 0.96
A newly recognized species in the Anopheles (Nyssorhynchus) albitarsis complex (Diptera: Culicidae) from Puerto Carreno, Colombia. Am J Trop Med Hyg (2007) 0.96
Improvement in chewing activity reduces energy intake in one meal and modulates plasma gut hormone concentrations in obese and lean young Chinese men. Am J Clin Nutr (2011) 0.95
6-Cyclo-hexyl-methyl-2-cyclo-hexyl-sul-fanyl-5-isopropyl-pyrimidin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online (2008) 0.94
Primary tumor standardized uptake value measured on F18-Fluorodeoxyglucose positron emission tomography is of prediction value for survival and local control in non-small-cell lung cancer receiving radiotherapy: meta-analysis. J Thorac Oncol (2014) 0.94
Cu(I) and Pb(II) complexes containing new tris(7-naphthyridyl)methane derivatives: synthesis, structures, spectroscopy and geometric conversion. Dalton Trans (2011) 0.94
The Arabidopsis U-box/ARM repeat E3 ligase AtPUB4 influences growth and degeneration of tapetal cells, and its mutation leads to conditional male sterility. Plant J (2013) 0.94
The long-term efficacy of neoadjuvant chemotherapy followed by radical hysterectomy compared with radical surgery alone or concurrent chemoradiotherapy on locally advanced-stage cervical cancer. Int J Gynecol Cancer (2011) 0.93
Dynamic changes in serum soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) and its gene polymorphisms are associated with sepsis prognosis. Inflammation (2012) 0.93
PMMA/PDMS valves and pumps for disposable microfluidics. Lab Chip (2009) 0.93
Anopheles belenrae, a potential vector of Plasmodium vivax in the Republic of Korea. J Am Mosq Control Assoc (2010) 0.92
Applications of molecular MRI and optical imaging in cancer. Future Med Chem (2010) 0.92
Expression of astrocyte elevated gene-1: a novel marker of the pathogenesis, progression, and poor prognosis for endometrial cancer. Int J Gynecol Cancer (2010) 0.91
(E)-N'-(3,5-Dibromo-2-hydroxy-benzyl-idene)nicotinohydrazide. Acta Crystallogr Sect E Struct Rep Online (2010) 0.91
Photodynamic inhibitory effects of three perylenequinones on human colorectal carcinoma cell line and primate embryonic stem cell line. World J Gastroenterol (2003) 0.91
6-Cyclo-hexyl-meth-yl-5-ethyl-2-[(2-oxo-2-phenyl-eth-yl)sulfan-yl]pyrimidin-4(3H)-one. Acta Crystallogr Sect E Struct Rep Online (2011) 0.90
Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents. Bioorg Med Chem Lett (2008) 0.88
Minimal fat renal angiomyolipoma: the initial study with contrast-enhanced ultrasonography. Ultrasound Med Biol (2012) 0.88
A Tourist-like MITE insertion in the upstream region of the BnFLC.A10 gene is associated with vernalization requirement in rapeseed (Brassica napus L.). BMC Plant Biol (2012) 0.88
Genetic structure of Anopheles (Nyssorhynchus) marajoara (Diptera: Culicidae) in Colombia. Am J Trop Med Hyg (2010) 0.87
Overcoming the blood-brain barrier for delivering drugs into the brain by using adenosine receptor nanoagonist. ACS Nano (2014) 0.86
New members of fluorescent 1,8-naphthyridine-based BF2 compounds: selective binding of BF2 with terminal bidentate N^N^O and N^C^O groups and tunable spectroscopy properties. Dalton Trans (2014) 0.86
Mitochondrial reactive oxygen species and nitric oxide-mediated cancer cell apoptosis in 2-butylamino-2-demethoxyhypocrellin B photodynamic treatment. Free Radic Biol Med (2006) 0.86
Identification of Egr1 as the oncostatin M-induced transcription activator that binds to sterol-independent regulatory element of human LDL receptor promoter. J Lipid Res (2002) 0.86
The Association Study between Twenty One Polymorphisms in Seven Candidate Genes and Coronary Heart Diseases in Chinese Han Population. PLoS One (2013) 0.86
Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population. Exp Lung Res (2013) 0.86
Investigation of the inclusions of puerarin and daidzin with beta-cyclodextrin by molecular dynamics simulation. J Phys Chem B (2010) 0.86
Longstanding living polymerization of ethylene: substituent effect on bridging carbon of 2-pyridinemethanamine nickel catalysts. Chem Commun (Camb) (2010) 0.85
Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemia. Mol Cancer Ther (2014) 0.85
Non-invasive imaging of endothelial progenitor cells in tumor neovascularization using a novel dual-modality paramagnetic/near-infrared fluorescence probe. PLoS One (2012) 0.84
Density functional theory calculations for resveratrol. Bioorg Med Chem Lett (2003) 0.84
SiLEA14, a novel atypical LEA protein, confers abiotic stress resistance in foxtail millet. BMC Plant Biol (2014) 0.84
Impact of hepatitis B virus infection on outcome following resection for intrahepatic cholangiocarcinoma. J Surg Oncol (2010) 0.84
Evaluation of chemotherapy response with serum squamous cell carcinoma antigen level in cervical cancer patients: a prospective cohort study. PLoS One (2013) 0.84
Polymorphisms in ERCC1 C8092A predict progression-free survival in metastatic/recurrent nasopharyngeal carcinoma treated with cisplatin-based chemotherapy. Cancer Chemother Pharmacol (2013) 0.84
[Prognosis of hepatocellular carcinoma: a study of 832 cases]. Zhonghua Zhong Liu Za Zhi (2013) 0.83
In vitro selection of highly efficient G-quadruplex-based DNAzymes. Anal Chem (2012) 0.83
Synthesis and antioxidant activity of novel Mannich base of 1,3,4-oxadiazole derivatives possessing 1,4-benzodioxan. Bioorg Med Chem (2013) 0.83
Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants. Hum Genet (2013) 0.83
Imaging acidosis in tumors using a pH-activated near-infrared fluorescence probe. Chem Commun (Camb) (2012) 0.83
MicroRNA-146a enhances Helicobacter pylori induced cell apoptosis in human gastric cancer epithelial cells. Asian Pac J Cancer Prev (2014) 0.83
Protective effects of estrogen against reperfusion arrhythmias following severe myocardial ischemia in rats. Circ J (2010) 0.83
Astrocyte elevated gene-1 (AEG-1) shRNA sensitizes Huaier polysaccharide (HP)-induced anti-metastatic potency via inactivating downstream P13K/Akt pathway as well as augmenting cell-mediated immune response. Tumour Biol (2013) 0.83
Cerebroside C increases tolerance to chilling injury and alters lipid composition in wheat roots. PLoS One (2013) 0.82
Comprehensive evaluation of SNP identification with the Restriction Enzyme-based Reduced Representation Library (RRL) method. BMC Genomics (2012) 0.82
Highly parallel single-molecule amplification approach based on agarose droplet polymerase chain reaction for efficient and cost-effective aptamer selection. Anal Chem (2011) 0.82
Serum HER 2 extracellular domain level is correlated with tissue HER 2 status in metastatic gastric or gastro-oesophageal junction adenocarcinoma. PLoS One (2013) 0.82
Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity. Bioorg Med Chem Lett (2010) 0.82
Thinning segregated graphene layers on high carbon solubility substrates of rhodium foils by tuning the quenching process. ACS Nano (2012) 0.82
Panax ginseng polysaccharide suppresses metastasis via modulating Twist expression in gastric cancer. Int J Biol Macromol (2013) 0.82
A novel genetic locus for familial febrile seizures and epilepsy on chromosome 3q26.2-q26.33. Hum Genet (2008) 0.81
Inferring functional interaction and transition patterns via dynamic Bayesian variable partition models. Hum Brain Mapp (2013) 0.81
Molecular mapping of a powdery mildew resistance gene in common wheat landrace Baihulu and its allelism with Pm24. Theor Appl Genet (2012) 0.81
Genome-wide analysis of long noncoding RNA profile in human gastric epithelial cell response to Helicobacter pylori. Jpn J Infect Dis (2014) 0.81
Laminins alpha2 and alpha4 in pancreatic acinar basement membranes are required for basal receptor localization. J Histochem Cytochem (2004) 0.81
Prodrug enzymes and their applications in image-guided therapy of cancer: tracking prodrug enzymes to minimize collateral damage. Drug Deliv Transl Res (2012) 0.81
Meta-analysis of the relationship between obestatin and ghrelin levels and the ghrelin/obestatin ratio with respect to obesity. Am J Med Sci (2011) 0.81
Astrocyte elevated gene-1: a novel independent prognostic biomarker for metastatic ovarian tumors. Tumour Biol (2014) 0.81
Accelerating haplotype-based genome-wide association study using perfect phylogeny and phase-known reference data. PLoS One (2011) 0.81
Astrocyte elevated gene-1 is a novel biomarker of epithelial-mesenchymal transition and progression of hepatocellular carcinoma in two China regions. Tumour Biol (2013) 0.81
Impact of COD/N ratio on nitrous oxide emission from microcosm wetlands and their performance in removing nitrogen from wastewater. Bioresour Technol (2009) 0.81
Overexpression of mitochondrial uncoupling protein conferred resistance to heat stress and Botrytis cinerea infection in tomato. Plant Physiol Biochem (2013) 0.80
Herb medicine Gan-fu-kang attenuates liver injury in a rat fibrotic model. J Ethnopharmacol (2010) 0.80
Nitrogen transformations and balance in constructed wetlands for slightly polluted river water treatment using different macrophytes. Environ Sci Pollut Res Int (2012) 0.80
Expression characteristics of proteins of the insulin-like growth factor axis in non-small cell lung cancer patients with preexisting type 2 diabetes mellitus. Asian Pac J Cancer Prev (2013) 0.80