Activation of mGluR2/3 underlies the effects of N-acetylcystein on amygdala-associated autism-like phenotypes in a valproate-induced rat model of autism.

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Published in Front Behav Neurosci on June 17, 2014

Authors

Yu-Wen Chen1, Hui-Ching Lin2, Ming-Chong Ng3, Ya-Hsin Hsiao1, Chao-Chuan Wang4, Po-Wu Gean1, Po See Chen5

Author Affiliations

1: Department of Pharmacology, College of Medicine, National Cheng-Kung University Tainan, Taiwan.
2: Department and Institute of Physiology, School of Medicine, National Yang-Ming University Taipei, Taiwan ; Brain Research Center, National Yang-Ming University Taipei, Taiwan.
3: Department of Psychiatry, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University Tainan, Taiwan.
4: Department of Anatomy, College of Medicine, Kaohsiung Medical University Kaohsiung, Taiwan.
5: Department of Psychiatry, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University Tainan, Taiwan ; Addiction Research Center, National Cheng Kung University Tainan, Taiwan.

Associated clinical trials:

Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1 (DoDNAC) | NCT04481048

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