Published in Tissue Barriers on April 03, 2014
Concomitant binding of Afadin to LGN and F-actin directs planar spindle orientation. Nat Struct Mol Biol (2016) 0.82
Cadherin controls nectin recruitment into adherens junctions by remodeling the actin cytoskeleton. J Cell Sci (2014) 0.78
Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions. Am J Physiol Gastrointest Liver Physiol (2015) 0.76
Tissue Barriers: Introducing an exciting new journal. Temperature (Austin) (2014) 0.75
EphA2 proteomics in human keratinocytes reveals a novel association with afadin and epidermal tight junctions. J Cell Sci (2016) 0.75
Mechanisms of epithelial cell-cell adhesion and cell compaction revealed by high-resolution tracking of E-cadherin-green fluorescent protein. J Cell Biol (1998) 5.03
A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis. PLoS Biol (2011) 3.76
Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein. J Cell Biol (1999) 3.47
Basal-to-apical cadherin flow at cell junctions. Nat Cell Biol (2006) 2.33
Biochemical and structural definition of the l-afadin- and actin-binding sites of alpha-catenin. J Biol Chem (2002) 2.31
The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin. Annu Rev Cell Dev Biol (2008) 2.30
The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins. Structure (2011) 2.19
Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis. J Cell Biol (1999) 1.96
Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteins. J Cell Biol (2000) 1.89
Principles of E-cadherin supramolecular organization in vivo. Curr Biol (2013) 1.79
P- and E-cadherin are in separate complexes in cells expressing both cadherins. Exp Cell Res (1993) 1.72
Interaction of nectin with afadin is necessary for its clustering at cell-cell contact sites but not for its cis dimerization or trans interaction. J Biol Chem (2000) 1.69
Endocytosis is required for E-cadherin redistribution at mature adherens junctions. Proc Natl Acad Sci U S A (2009) 1.67
Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions. J Cell Biol (1999) 1.62
Spontaneous assembly and active disassembly balance adherens junction homeostasis. Proc Natl Acad Sci U S A (2010) 1.59
Prominent role of the Ig-like V domain in trans-interactions of nectins. Nectin3 and nectin 4 bind to the predicted C-C'-C"-D beta-strands of the nectin1 V domain. J Biol Chem (2002) 1.54
Regulation of E-cadherin endocytosis by nectin through afadin, Rap1, and p120ctn. J Biol Chem (2005) 1.52
Absence of the tight junctional protein AF-6 disrupts epithelial cell-cell junctions and cell polarity during mouse development. Curr Biol (1999) 1.52
Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments. J Cell Biol (2004) 1.52
Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cells. J Biol Chem (2005) 1.46
Stable and unstable cadherin dimers: mechanisms of formation and roles in cell adhesion. Mol Biol Cell (2007) 1.42
Endocytosis of cadherin from intracellular junctions is the driving force for cadherin adhesive dimer disassembly. Mol Biol Cell (2006) 1.41
Binding to F-actin guides cadherin cluster assembly, stability, and movement. J Cell Biol (2013) 1.23
Cellular localization of nectin-1 and glycoprotein D during herpes simplex virus infection. J Virol (2003) 1.21
Antagonistic and agonistic effects of an extracellular fragment of nectin on formation of E-cadherin-based cell-cell adhesion. Genes Cells (2003) 1.20
Involvement of LMO7 in the association of two cell-cell adhesion molecules, nectin and E-cadherin, through afadin and alpha-actinin in epithelial cells. J Biol Chem (2004) 1.19
Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells. J Biol Chem (2009) 1.15
Cadherin exits the junction by switching its adhesive bond. J Cell Biol (2011) 1.12
Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis. Development (2010) 1.09
Mutations in PVRL4, encoding cell adhesion molecule nectin-4, cause ectodermal dysplasia-syndactyly syndrome. Am J Hum Genet (2010) 1.06
Regulation of epithelial wound closure and intercellular adhesion by interaction of AF6 with actin cytoskeleton. J Cell Sci (2006) 1.05
Nectin ectodomain structures reveal a canonical adhesive interface. Nat Struct Mol Biol (2012) 1.04
Crystal Structure of the cis-Dimer of Nectin-1: implications for the architecture of cell-cell junctions. J Biol Chem (2011) 1.01
ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions. J Biol Chem (2002) 0.98
Afadin controls p120-catenin-ZO-1 interactions leading to endothelial barrier enhancement by oxidized phospholipids. J Cell Physiol (2012) 0.97
Structural determinants of Junctional Adhesion Molecule A (JAM-A) function and mechanisms of intracellular signaling. Curr Opin Cell Biol (2009) 0.96
The cell adhesion gene PVRL3 is associated with congenital ocular defects. Hum Genet (2011) 0.96
Amino-terminal domain of classic cadherins determines the specificity of the adhesive interactions. J Cell Sci (2000) 0.94
Involvement of afadin in barrier function and homeostasis of mouse intestinal epithelia. J Cell Sci (2011) 0.94
Adherens junction assembly. Subcell Biochem (2012) 0.91
Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion. Proc Natl Acad Sci U S A (2012) 0.90
Involvement of nectin in the localization of IQGAP1 at the cell-cell adhesion sites through the actin cytoskeleton in Madin-Darby canine kidney cells. Oncogene (2003) 0.90
PICK-1: a scaffold protein that interacts with Nectins and JAMs at cell junctions. FEBS Lett (2005) 0.87
The adherens junction: a mosaic of cadherin and nectin clusters bundled by actin filaments. J Invest Dermatol (2013) 0.82
Role of AF6 protein in cell-to-cell spread of Herpes simplex virus 1. FEBS Lett (2007) 0.81