Published in Front Immunol on July 22, 2014
A principle of organization which facilitates broad Lamarckian-like adaptations by improvisation. Biol Direct (2015) 0.83
Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma. Oncoimmunology (2015) 0.82
The RB tumor suppressor at the intersection of proliferation and immunity: relevance to disease immune evasion and immunotherapy. Cell Cycle (2015) 0.77
IL-13 from intraepithelial lymphocytes regulates tissue homeostasis and protects against carcinogenesis in the skin. Nat Commun (2016) 0.75
Long noncoding RNA FOXD3-AS1 regulates oxidative stress-induced apoptosis via sponging microRNA-150. FASEB J (2017) 0.75
Inflammation and cancer: back to Virchow? Lancet (2001) 27.40
The DNA-damage response in human biology and disease. Nature (2009) 17.86
Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med (1986) 17.64
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity (2005) 14.95
The danger model: a renewed sense of self. Science (2002) 13.85
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature (2001) 11.03
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature (2008) 8.22
The three Es of cancer immunoediting. Annu Rev Immunol (2004) 8.20
Natural innate and adaptive immunity to cancer. Annu Rev Immunol (2011) 7.09
Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature (2002) 7.07
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci U S A (1998) 6.82
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol (2011) 6.73
Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus. Nat Immunol (2009) 6.62
Hedgehog signaling in development and cancer. Dev Cell (2008) 6.60
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity (2001) 6.56
Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med (2002) 6.48
Regulation of cutaneous malignancy by gammadelta T cells. Science (2001) 5.83
House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med (2009) 5.55
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells. J Exp Med (2008) 5.42
Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis. Nature (2007) 4.68
Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity. Nature (2012) 4.64
Differential tumor surveillance by natural killer (NK) and NKT cells. J Exp Med (2000) 4.45
The age of cancer. Nature (2000) 4.32
Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. J Clin Invest (2009) 4.10
A role for TSLP in the development of inflammation in an asthma model. J Exp Med (2005) 4.08
Neutralizing tumor-promoting chronic inflammation: a magic bullet? Science (2013) 3.91
Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med (2007) 3.91
Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med (2005) 3.82
Six-of-the-best: unique contributions of γδ T cells to immunology. Nat Rev Immunol (2013) 3.77
Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells. J Exp Med (2007) 3.66
IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med (2007) 3.66
Skin immune sentinels in health and disease. Nat Rev Immunol (2009) 3.52
A role for skin gammadelta T cells in wound repair. Science (2002) 3.51
Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. J Exp Med (2006) 3.36
Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev (2008) 3.33
IL-33, a potent inducer of adaptive immunity to intestinal nematodes. J Immunol (2008) 3.31
Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors. Immunity (1994) 3.24
Gammadelta T cells and the lymphoid stress-surveillance response. Immunity (2009) 3.23
Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel. Nat Immunol (2010) 3.15
Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis. Nat Immunol (2008) 3.14
Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation. J Exp Med (2011) 3.12
Effect of NKG2D ligand expression on host immune responses. Immunol Rev (2010) 3.08
Regulation of ligands for the NKG2D activating receptor. Annu Rev Immunol (2013) 2.98
Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome. Nat Genet (2000) 2.85
Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4. Science (1991) 2.81
Mast cells can enhance resistance to snake and honeybee venoms. Science (2006) 2.72
Sensing the outside world: TSLP regulates barrier immunity. Nat Immunol (2010) 2.72
Eosinophils: changing perspectives in health and disease. Nat Rev Immunol (2012) 2.69
Protection of the intestinal mucosa by intraepithelial gamma delta T cells. Proc Natl Acad Sci U S A (2002) 2.69
Commensal-dependent expression of IL-25 regulates the IL-23-IL-17 axis in the intestine. J Exp Med (2008) 2.63
An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma. Immunity (2011) 2.57
DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity (1996) 2.56
IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1. J Biol Chem (2001) 2.50
The light and dark sides of intestinal intraepithelial lymphocytes. Nat Rev Immunol (2011) 2.46
DNA released from dying host cells mediates aluminum adjuvant activity. Nat Med (2011) 2.41
The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol (2011) 2.33
Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells. Nat Genet (2008) 2.31
Cancer; a biological approach. I. The processes of control. Br Med J (1957) 2.29
The molecular interaction of CAR and JAML recruits the central cell signal transducer PI3K. Science (2010) 2.26
Epithelial stem cells, wound healing and cancer. Nat Rev Cancer (2012) 2.23
Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis. Proc Natl Acad Sci U S A (2010) 2.22
The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling. Nat Immunol (2010) 2.20
Epithelial decision makers: in search of the 'epimmunome'. Nat Immunol (2010) 2.19
Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity (2007) 2.15
A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis. J Exp Med (2013) 2.11
Resident skin-specific gammadelta T cells provide local, nonredundant regulation of cutaneous inflammation. J Exp Med (2002) 2.08
Nectins and nectin-like molecules: roles in cell adhesion, migration, and polarization. Cancer Sci (2003) 2.03
The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation. Science (2010) 2.02
Induction of T helper type 2 immunity by a point mutation in the LAT adaptor. Science (2002) 2.01
Allergic host defences. Nature (2012) 1.99
The CD100 receptor interacts with its plexin B2 ligand to regulate epidermal γδ T cell function. Immunity (2012) 1.98
Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths. Nat Rev Immunol (2013) 1.96
The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice. Immunity (2000) 1.96
Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in alpha beta(+) T cells. Nature (1994) 1.94
Type VII collagen is required for Ras-driven human epidermal tumorigenesis. Science (2005) 1.94
Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1. Nat Immunol (2004) 1.92
Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. Immunity (2013) 1.88
Determinants of allergenicity. J Allergy Clin Immunol (2009) 1.87
Inflammasomes in carcinogenesis and anticancer immune responses. Nat Immunol (2012) 1.85
Programmed cell removal: a new obstacle in the road to developing cancer. Nat Rev Cancer (2011) 1.84
Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome. J Exp Med (2009) 1.83
Nod2-dependent Th2 polarization of antigen-specific immunity. J Immunol (2008) 1.78
The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy. Science (2011) 1.78
Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma. Blood (2002) 1.76
Cancer: a biological approach. III. Viruses associated with neoplastic conditions. IV. Practical applications. Br Med J (1957) 1.74
Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo. Proc Natl Acad Sci U S A (2009) 1.72
A beneficial role for immunoglobulin E in host defense against honeybee venom. Immunity (2013) 1.71
The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch. Cell (2013) 1.71
Autophagy and cellular immune responses. Immunity (2013) 1.71
Skin gammadelta T-cell functions in homeostasis and wound healing. Immunol Rev (2007) 1.69
Gene polymorphism in Netherton and common atopic disease. Nat Genet (2001) 1.66
Silica crystals and aluminum salts regulate the production of prostaglandin in macrophages via NALP3 inflammasome-independent mechanisms. Immunity (2011) 1.65
Viral modulation of NK cell immunity. Nat Rev Microbiol (2005) 1.62
Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells. Immunity (2011) 1.62
Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride. Hepatology (2009) 1.61
AllergoOncology: the role of IgE-mediated allergy in cancer. Allergy (2008) 1.59
The function of allergy: immunological defense against toxins. Q Rev Biol (1991) 1.58
Constitutive and inducible expression of b7 family of ligands by human airway epithelial cells. Am J Respir Cell Mol Biol (2005) 1.56