SAMSN1 is a tumor suppressor gene in multiple myeloma.

PubWeight™: 0.82‹?›

🔗 View Article (PMC 4198825)

Published in Neoplasia on July 01, 2014

Authors

Jacqueline E Noll1, Duncan R Hewett1, Sharon A Williams1, Kate Vandyke1, Chung Kok2, Luen B To3, Andrew C W Zannettino4

Author Affiliations

1: Myeloma Research Laboratory, School of Medical Sciences, Faculty of Health Science, University of Adelaide, Adelaide, Australia; Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
2: Acute Myeloid Leukaemia Laboratory, Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
3: Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia.
4: Myeloma Research Laboratory, School of Medical Sciences, Faculty of Health Science, University of Adelaide, Adelaide, Australia; Department of Haematology, Centre for Cancer Biology, SA Pathology, Adelaide, Australia. Electronic address: andrew.zannettino@adelaide.edu.au.

Articles cited by this

Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27

Cancer statistics, 2012. CA Cancer J Clin (2012) 87.38

A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat Genet (1997) 12.94

A long-term study of prognosis in monoclonal gammopathy of undetermined significance. N Engl J Med (2002) 8.63

Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome. Blood (2007) 5.55

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review. Leukemia (2009) 4.91

Clinical and biologic implications of recurrent genomic aberrations in myeloma. Blood (2003) 4.67

A monoclonal gammopathy precedes multiple myeloma in most patients. Blood (2009) 3.98

AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies. Cancer Cell (2008) 2.84

Idiopathic paraproteinemia. II. Transplantation of the paraprotein-producing clone from old to young C57BL/KaLwRij mice. J Immunol (1979) 2.60

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression. Blood (2002) 2.38

The structure and function of proline recognition domains. Sci STKE (2003) 2.25

Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis. Blood (2003) 2.23

Animal model of human disease. Multiple myeloma. Am J Pathol (1988) 2.08

Chromosome 13 abnormalities identified by FISH analysis and serum beta2-microglobulin produce a powerful myeloma staging system for patients receiving high-dose therapy. Blood (2001) 1.95

SAM domains: uniform structure, diversity of function. Trends Biochem Sci (2003) 1.94

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma. Blood (2007) 1.93

Host-derived adiponectin is tumor-suppressive and a novel therapeutic target for multiple myeloma and the associated bone disease. Blood (2011) 1.88

Prognostic value of chromosome 1q21 gain by fluorescent in situ hybridization and increase CKS1B expression in myeloma. Leukemia (2006) 1.71

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma. Blood (2010) 1.67

A murine model of human myeloma bone disease. Bone (1997) 1.53

Idiopathic paraproteinaemia. I. Studies in an animal model--the ageing C57BL/KaLwRij mouse. Clin Exp Immunol (1978) 1.48

TWIST family of basic helix-loop-helix transcription factors mediate human mesenchymal stem cell growth and commitment. Stem Cells (2009) 1.47

Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells. Cancer Res (2008) 1.46

Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer. Genes Chromosomes Cancer (2008) 1.41

Expected long-term survival of patients diagnosed with multiple myeloma in 2006-2010. Haematologica (2009) 1.39

Organ involvement and phenotypic adhesion profile of 5T2 and 5T33 myeloma cells in the C57BL/KaLwRij mouse. Br J Cancer (1997) 1.30

A simple and efficient procedure for generating stable expression libraries by cDNA cloning in a retroviral vector. Mol Cell Biol (1994) 1.30

Regulated proliferation of primitive hematopoietic progenitor cells in long-term human marrow cultures. Blood (1985) 1.28

The progression from MGUS to smoldering myeloma and eventually to multiple myeloma involves a clonal expansion of genetically abnormal plasma cells. Clin Cancer Res (2011) 1.28

Detection of myeloma in skeleton of mice by whole-body optical fluorescence imaging. Mol Cancer Ther (2007) 1.28

PSGL-1-mediated adhesion of human hematopoietic progenitors to P-selectin results in suppression of hematopoiesis. Immunity (1999) 1.27

Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas. Blood (2007) 1.23

Differential repetitive DNA methylation in multiple myeloma molecular subgroups. Carcinogenesis (2009) 1.18

Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation. J Clin Invest (1995) 1.13

Advances in the diagnosis, classification, risk stratification, and management of monoclonal gammopathy of undetermined significance: implications for recategorizing disease entities in the presence of evolving scientific evidence. Mayo Clin Proc (2010) 1.11

HACS1 encodes a novel SH3-SAM adaptor protein differentially expressed in normal and malignant hematopoietic cells. Oncogene (2001) 1.11

Myeloma is characterized by stage-specific alterations in DNA methylation that occur early during myelomagenesis. J Immunol (2013) 1.07

The SH3-SAM adaptor HACS1 is up-regulated in B cell activation signaling cascades. J Exp Med (2004) 1.05

A murine model of myeloma that allows genetic manipulation of the host microenvironment. Dis Model Mech (2009) 1.04

Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma. Haematologica (2011) 1.01

Targeted disruption of the CXCL12/CXCR4 axis inhibits osteolysis in a murine model of myeloma-associated bone loss. J Bone Miner Res (2009) 1.00

Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells. Haematologica (2013) 0.97

Enhanced adaptive immunity in mice lacking the immunoinhibitory adaptor Hacs1. FASEB J (2009) 0.89

Immunoinhibitory adapter protein Src homology domain 3 lymphocyte protein 2 (SLy2) regulates actin dynamics and B cell spreading. J Biol Chem (2011) 0.85

Osteoblast gene expression in rat long bones: effects of ovariectomy and dihydrotestosterone on mRNA levels. Calcif Tissue Int (2000) 0.81

Translocation t(11;14) (q13;q32) and genomic imbalances in multi-ethnic multiple myeloma patients: a Malaysian study. Hematol Rep (2012) 0.81