Gefitinib treatment in EGFR mutated caucasian NSCLC: circulating-free tumor DNA as a surrogate for determination of EGFR status.

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Published in J Thorac Oncol on September 01, 2014

Authors

Jean-Yves Douillard1, Gyula Ostoros, Manuel Cobo, Tudor Ciuleanu, Rebecca Cole, Gael McWalter, Jill Walker, Simon Dearden, Alan Webster, Tsveta Milenkova, Rose McCormack

Author Affiliations

1: *Institut de Cancerologie, Centre René Gauducheau, Nantes, France; †National Koranyi Institute of Pulmonology, Budapest, Hungary; ‡Hospital Regional Universitario, Malaga, Spain; §Institutul Oncologic Prof. Dr. Ion Chiricuta and University of Medicine and Pharmacy Iuliu Hatieganu, Cluj-Napoca, Romania; and ‖AstraZeneca, Macclesfield, United Kingdom.

Associated clinical trials:

Efficacy, Safety, Tolerability of Gefitinib as 1st Line in Caucasian Patients With EGFR Mutation Positive Advanced NSCLC (IFUM) | NCT01203917

A Study of Avastin in Combination With Chemotherapy for Treatment of Colorectal Cancer and Non-Small Cell Lung Cancer (ARIES) (ARIES) | NCT00388206

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