Paul W O'Toole

Author PubWeight™ 110.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Gut microbiota composition correlates with diet and health in the elderly. Nature 2012 6.94
2 Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci U S A 2010 5.02
3 Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine. PLoS One 2009 4.93
4 Comparison of two next-generation sequencing technologies for resolving highly complex microbiota composition using tandem variable 16S rRNA gene regions. Nucleic Acids Res 2010 4.17
5 Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118. Proc Natl Acad Sci U S A 2007 3.32
6 Genome-scale analyses of health-promoting bacteria: probiogenomics. Nat Rev Microbiol 2008 3.25
7 Diversity of bifidobacteria within the infant gut microbiota. PLoS One 2012 2.71
8 An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota. Gut 2011 2.49
9 Multireplicon genome architecture of Lactobacillus salivarius. Proc Natl Acad Sci U S A 2006 2.43
10 Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity. Gut 2012 2.24
11 Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor. Proc Natl Acad Sci U S A 2011 2.22
12 The Bifidobacterium dentium Bd1 genome sequence reflects its genetic adaptation to the human oral cavity. PLoS Genet 2009 1.64
13 Molecular dialogue between the human gut microbiota and the host: a Lactobacillus and Bifidobacterium perspective. Cell Mol Life Sci 2013 1.57
14 Diversity of the genus Lactobacillus revealed by comparative genomics of five species. Microbiology 2006 1.52
15 The gut microbiota and its relationship to diet and obesity: new insights. Gut Microbes 2012 1.52
16 Techniques used to characterize the gut microbiota: a guide for the clinician. Nat Rev Gastroenterol Hepatol 2012 1.51
17 Comparative and functional analysis of sortase-dependent proteins in the predicted secretome of Lactobacillus salivarius UCC118. Appl Environ Microbiol 2006 1.48
18 The genus Lactobacillus--a genomic basis for understanding its diversity. FEMS Microbiol Lett 2007 1.45
19 Clostridium difficile carriage in elderly subjects and associated changes in the intestinal microbiota. J Clin Microbiol 2011 1.34
20 Phylogenomic data support a seventh order of Methylotrophic methanogens and provide insights into the evolution of Methanogenesis. Genome Biol Evol 2013 1.33
21 Categorization of the gut microbiota: enterotypes or gradients? Nat Rev Microbiol 2012 1.31
22 Genomic diversity of Lactobacillus salivarius. Appl Environ Microbiol 2010 1.25
23 Genome sequence of "Candidatus Methanomethylophilus alvus" Mx1201, a methanogenic archaeon from the human gut belonging to a seventh order of methanogens. J Bacteriol 2012 1.24
24 The microbial eukaryote Blastocystis is a prevalent and diverse member of the healthy human gut microbiota. FEMS Microbiol Ecol 2014 1.21
25 Novel chromosomally encoded multidrug efflux transporter MdeA in Staphylococcus aureus. Antimicrob Agents Chemother 2004 1.21
26 Comparative genomics highlights the unique biology of Methanomassiliicoccales, a Thermoplasmatales-related seventh order of methanogenic archaea that encodes pyrrolysine. BMC Genomics 2014 1.18
27 Lactobacillus phylogenomics--towards a reclassification of the genus. Int J Syst Evol Microbiol 2008 1.14
28 Molecular basis of the interaction between the flagellar export proteins FliI and FliH from Helicobacter pylori. J Biol Chem 2005 1.13
29 Distribution of megaplasmids in Lactobacillus salivarius and other lactobacilli. J Bacteriol 2007 1.11
30 Characterization of pro-inflammatory flagellin proteins produced by Lactobacillus ruminis and related motile Lactobacilli. PLoS One 2012 1.09
31 Characterization of endogenous plasmids from Lactobacillus salivarius UCC118. Appl Environ Microbiol 2008 1.04
32 Allelic variation of bile salt hydrolase genes in Lactobacillus salivarius does not determine bile resistance levels. J Bacteriol 2009 1.01
33 Diet-microbiota interactions and their implications for healthy living. Nutrients 2013 1.01
34 Targeting the microbiota to address diet-induced obesity: a time dependent challenge. PLoS One 2013 1.01
35 The FliK protein and flagellar hook-length control. Protein Sci 2007 1.00
36 Effect of Lactobacillus salivarius bacteriocin Abp118 on the mouse and pig intestinal microbiota. PLoS One 2012 1.00
37 Helicobacter pylori flagellar hook-filament transition is controlled by a FliK functional homolog encoded by the gene HP0906. J Bacteriol 2005 0.99
38 Alterations in intestinal microbiota of elderly Irish subjects post-antibiotic therapy. J Antimicrob Chemother 2012 0.99
39 Genome Sequence of "Candidatus Methanomassiliicoccus intestinalis" Issoire-Mx1, a Third Thermoplasmatales-Related Methanogenic Archaeon from Human Feces. Genome Announc 2013 0.97
40 Strain-specific inhibition of Helicobacter pylori by Lactobacillus salivarius and other lactobacilli. J Antimicrob Chemother 2008 0.95
41 Functional metagenomic profiling of intestinal microbiome in extreme ageing. Aging (Albany NY) 2013 0.95
42 Genome sequences and comparative genomics of two Lactobacillus ruminis strains from the bovine and human intestinal tracts. Microb Cell Fact 2011 0.95
43 Microbial diversity in the human intestine and novel insights from metagenomics. Front Biosci (Landmark Ed) 2009 0.94
44 Resource partitioning in relation to cohabitation of Lactobacillus species in the mouse forestomach. ISME J 2011 0.93
45 Posttranscriptional regulation of flagellin synthesis in Helicobacter pylori by the RpoN chaperone HP0958. J Bacteriol 2008 0.92
46 Mechanism of protection of transepithelial barrier function by Lactobacillus salivarius: strain dependence and attenuation by bacteriocin production. Am J Physiol Gastrointest Liver Physiol 2012 0.91
47 The microbiota link to irritable bowel syndrome: an emerging story. Gut Microbes 2012 0.91
48 The individual-specific and diverse nature of the preterm infant microbiota. Arch Dis Child Fetal Neonatal Ed 2013 0.91
49 Detection and genomic characterization of motility in Lactobacillus curvatus: confirmation of motility in a species outside the Lactobacillus salivarius clade. Appl Environ Microbiol 2015 0.90
50 Lactobacillus salivarius modulates cytokine induction and virulence factor gene expression in Helicobacter pylori. J Med Microbiol 2009 0.89
51 The human gut chip "HuGChip", an explorative phylogenetic microarray for determining gut microbiome diversity at family level. PLoS One 2013 0.88
52 Challenges and implications for biomedical research and intervention studies in older populations: insights from the ELDERMET study. Gerontology 2012 0.88
53 Model for substrate interactions in C5a peptidase from Streptococcus pyogenes: A 1.9 A crystal structure of the active form of ScpA. J Mol Biol 2009 0.88
54 Pro-inflammatory flagellin proteins of prevalent motile commensal bacteria are variably abundant in the intestinal microbiome of elderly humans. PLoS One 2013 0.87
55 Production of multiple bacteriocins from a single locus by gastrointestinal strains of Lactobacillus salivarius. J Bacteriol 2011 0.87
56 Cloning and expression of an oligopeptidase, PepO, with novel specificity from Lactobacillus rhamnosus HN001 (DR20). Appl Environ Microbiol 2002 0.87
57 HP0958 is an essential motility gene in Helicobacter pylori. FEMS Microbiol Lett 2005 0.87
58 Influence of adhesion and bacteriocin production by Lactobacillus salivarius on the intestinal epithelial cell transcriptional response. Appl Environ Microbiol 2012 0.86
59 Lactobacillus: host-microbe relationships. Curr Top Microbiol Immunol 2013 0.86
60 Carbohydrate catabolic flexibility in the mammalian intestinal commensal Lactobacillus ruminis revealed by fermentation studies aligned to genome annotations. Microb Cell Fact 2011 0.86
61 The role of the microbiota in ageing: current state and perspectives. Wiley Interdiscip Rev Syst Biol Med 2015 0.85
62 Polyphasic analysis indicates that Lactobacillus salivarius subsp. salivarius and Lactobacillus salivarius subsp. salicinius do not merit separate subspecies status. Int J Syst Evol Microbiol 2006 0.85
63 Next-generation sequencing technologies and their impact on microbial genomics. Brief Funct Genomics 2013 0.85
64 Isolation of lactococcal prolate phage-phage recombinants by an enrichment strategy reveals two novel host range determinants. J Bacteriol 2005 0.85
65 Transcriptional and metabolomic consequences of LuxS inactivation reveal a metabolic rather than quorum-sensing role for LuxS in Lactobacillus reuteri 100-23. J Bacteriol 2012 0.84
66 HorB (HP0127) is a gastric epithelial cell adhesin. Helicobacter 2007 0.83
67 Catabolic flexibility of mammalian-associated lactobacilli. Microb Cell Fact 2013 0.83
68 Fibrinogen-binding and platelet-aggregation activities of a Lactobacillus salivarius septicaemia isolate are mediated by a novel fibrinogen-binding protein. Mol Microbiol 2012 0.83
69 Bifidobacterium breve with α-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome. PLoS One 2012 0.82
70 The 2.2-Å structure of the HP0958 protein from Helicobacter pylori reveals a kinked anti-parallel coiled-coil hairpin domain and a highly conserved ZN-ribbon domain. J Mol Biol 2010 0.82
71 Prevalence and characterization of Clostridium perfringens from the faecal microbiota of elderly Irish subjects. J Med Microbiol 2012 0.80
72 Microbiota diversity and stability of the preterm neonatal ileum and colon of two infants. Microbiologyopen 2013 0.80
73 Sequence diversity and functional conservation of the origin of replication in lactococcal prolate phages. Appl Environ Microbiol 2003 0.80
74 Draft genome sequences of Helicobacter pylori strains 17874 and P79. J Bacteriol 2012 0.79
75 The dissemination of C10 cysteine protease genes in Bacteroides fragilis by mobile genetic elements. BMC Microbiol 2010 0.79
76 Evaluating the latest high-throughput molecular techniques for the exploration of microbial gut communities. Gut Microbes 2010 0.79
77 Special issue: The Human Intestinal Microbiota. Microbiology 2010 0.78
78 Host-microbe interactions and spatial variation of cancer in the gut. Nat Rev Cancer 2014 0.78
79 Genetic tools for investigating the biology of commensal lactobacilli. Front Biosci (Landmark Ed) 2009 0.78
80 Structure of ribose 5-phosphate isomerase from the probiotic bacterium Lactobacillus salivarius UCC118. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 0.78
81 Essentiality of the early transcript in the replication origin of the lactococcal prolate phage c2. J Bacteriol 2004 0.76
82 Draft Genome Sequence of Lactobacillus crispatus EM-LC1, an Isolate with Antimicrobial Activity Cultured from an Elderly Subject. Genome Announc 2013 0.76
83 Molecular methods for studying methanogens of the human gastrointestinal tract: current status and future directions. Appl Microbiol Biotechnol 2015 0.76
84 The HP0256 gene product is involved in motility and cell envelope architecture of Helicobacter pylori. BMC Microbiol 2010 0.76
85 The effect of environmental conditions on expression of Bacteroides fragilis and Bacteroides thetaiotaomicron C10 protease genes. BMC Microbiol 2012 0.76
86 Effect of FliK mutation on the transcriptional activity of the {sigma}54 sigma factor RpoN in Helicobacter pylori. Microbiology 2009 0.76
87 The Genome of the Predominant Equine Lactobacillus Species, Lactobacillus equi, Is Reflective of Its Lifestyle Adaptations to an Herbivorous Host. Genome Announc 2014 0.75
88 Phenotypic variation of Helicobacter pylori isolates from geographically distinct regions detected by lectin typing. J Clin Microbiol 2002 0.75
89 Dietary glycaemic load associated with cognitive performance in elderly subjects. Eur J Nutr 2014 0.75