Published in Nagoya J Med Sci on February 01, 2014
Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients. Oxid Med Cell Longev (2016) 1.38
Association between the NF-E2 Related Factor 2 Gene Polymorphism and Oxidative Stress, Anti-Oxidative Status, and Newly-Diagnosed Type 2 Diabetes Mellitus in a Chinese Population. Int J Mol Sci (2015) 0.78
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev (1999) 13.43
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An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen. Proc Natl Acad Sci U S A (2001) 4.49
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol Sci (2001) 4.02
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Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury. FASEB J (2007) 2.65
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The transcription factor NRF2 protects against pulmonary fibrosis. FASEB J (2004) 2.43
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Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. Oncogene (2001) 2.21
Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema. Thorax (2008) 1.70
Polymerase chain reaction with confronting two-pair primers for polymorphism genotyping. Jpn J Cancer Res (2000) 1.67
The role of heme oxygenase-1 in pulmonary disease. Am J Respir Cell Mol Biol (2006) 1.59
Identification of polymorphisms in the promoter region of the human NRF2 gene. Biochem Biophys Res Commun (2004) 1.40
Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells. J Biol Chem (2001) 1.39
Enhanced NAD(P)H:quinone reductase activity prevents glutamate toxicity produced by oxidative stress. J Neurochem (1991) 1.08
Level and course of FEV1 in relation to polymorphisms in NFE2L2 and KEAP1 in the general population. Respir Res (2009) 1.03
A randomized trial of adjuvant chemotherapy with uracil-tegafur for adenocarcinoma of the lung. N Engl J Med (2004) 6.36
Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature (2002) 5.62
Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population. Sci Transl Med (2009) 2.25
Glomerular hyperfiltration in prediabetes and prehypertension. Nephrol Dial Transplant (2011) 2.17
Height, weight, menstrual and reproductive factors and risk of gastric cancer among Japanese postmenopausal women: analysis by subsite and histologic subtype. Int J Cancer (2002) 1.74
Multivariate analysis of C-5 palsy incidence after cervical posterior fusion with instrumentation. J Neurosurg Spine (2012) 1.68
Allogeneic hematopoietic stem cell transplantation from family members other than HLA-identical siblings over the last decade (1991-2000). Blood (2003) 1.60
The relation between cognitive function and UI in healthy, community-dwelling, middle-aged and elderly people. Arch Gerontol Geriatr (2010) 1.41
Association of Lewis and Secretor gene polymorphisms and Helicobacter pylori seropositivity among Japanese-Brazilians. J Gastroenterol (2004) 1.41
Gene-environment interactions between the smoking habit and polymorphisms in the DNA repair genes, APE1 Asp148Glu and XRCC1 Arg399Gln, in Japanese lung cancer risk. Carcinogenesis (2004) 1.39
Association of a polymorphism of the phospholipase D2 gene with the prevalence of colorectal cancer. J Mol Med (Berl) (2003) 1.37
Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity. J Am Soc Nephrol (2002) 1.32
Common dysfunctional variants in ABCG2 are a major cause of early-onset gout. Sci Rep (2013) 1.28
An intervention study of smoking cessation with feedback on genetic cancer susceptibility in Japan. Prev Med (2005) 1.27
Back muscle strength and spinal mobility are predictors of quality of life in middle-aged and elderly males. Eur Spine J (2010) 1.25
Interactions of human organic anion transporters with diuretics. J Pharmacol Exp Ther (2003) 1.25
Protein-bound uremic toxins in hemodialysis patients measured by liquid chromatography/tandem mass spectrometry and their effects on endothelial ROS production. Anal Bioanal Chem (2012) 1.25
Oral health status and health-related quality of life: a systematic review. J Oral Sci (2006) 1.24
Two immunochemical assays to measure advanced glycation end-products in serum from dialysis patients. Clin Chem Lab Med (2005) 1.23
Indoxyl sulfate upregulates expression of ICAM-1 and MCP-1 by oxidative stress-induced NF-kappaB activation. Am J Nephrol (2010) 1.22
Associations between circulating microRNAs (miR-21, miR-34a, miR-122 and miR-451) and non-alcoholic fatty liver. Clin Chim Acta (2013) 1.21
Epidemiology of pancreatic cancer in Japan: a nested case-control study from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC). Int J Epidemiol (2003) 1.21
Metabolomic search for uremic toxins as indicators of the effect of an oral sorbent AST-120 by liquid chromatography/tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2010) 1.20
Baseline data of Shizuoka area in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study). Nagoya J Med Sci (2009) 1.19
Multivariate analysis of the pathologic features of esophageal squamous cell cancer: tumor budding is a significant independent prognostic factor. Ann Surg Oncol (2008) 1.19
Indoxyl sulphate promotes aortic calcification with expression of osteoblast-specific proteins in hypertensive rats. Nephrol Dial Transplant (2008) 1.17
Elevated C-reactive protein levels in patients with polypoidal choroidal vasculopathy and patients with neovascular age-related macular degeneration. Ophthalmology (2007) 1.15
A Model of Practical Cancer Prevention for Out-patients Visiting a Hospital: the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC). Asian Pac J Cancer Prev (2000) 1.14
Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells. Nephrol Dial Transplant (2009) 1.14
Indoxyl sulfate inhibits nitric oxide production and cell viability by inducing oxidative stress in vascular endothelial cells. Am J Nephrol (2009) 1.14
BMI-1 is highly expressed in M0-subtype acute myeloid leukemia. Int J Hematol (2005) 1.13
Bifidobacterium in gastro-resistant seamless capsule reduces serum levels of indoxyl sulfate in patients on hemodialysis. Am J Kidney Dis (2003) 1.12
Quantum dots labeling using octa-arginine peptides for imaging of adipose tissue-derived stem cells. Biomaterials (2010) 1.08
ABO genotype and the risk of gastric cancer, atrophic gastritis, and Helicobacter pylori infection. Cancer Epidemiol Biomarkers Prev (2011) 1.06
Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. J Pharmacol Exp Ther (2002) 1.05
Metabolomic analysis of uremic toxins by liquid chromatography/electrospray ionization-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 1.05
Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma. Haematologica (2003) 1.04
HIV prevalence and factors associated with HIV infection among male injection drug users under 30: a cross-sectional study in Long An, Vietnam. BMC Public Health (2006) 1.03
Linguistic adaptation and validation of the General Oral Health Assessment Index (GOHAI) in an elderly Japanese population. J Public Health Dent (2006) 1.02
NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells. Am J Physiol Cell Physiol (2011) 1.02
Common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility. Hum Cell (2013) 1.02
No association between EGF gene polymorphism and gastric cancer. Cancer Epidemiol Biomarkers Prev (2005) 1.01
Potential cardiovascular risk factors in chronic kidney disease: AGEs, total homocysteine and metabolites, and the C-reactive protein. Kidney Int (2004) 1.01
Urinary excretion of 3-phenoxybenzoic acid in middle-aged and elderly general population of Japan. Environ Res (2008) 1.00
Association of prostate stem cell antigen gene polymorphisms with the risk of stomach cancer in Japanese. Int J Cancer (2009) 1.00
Transforming growth factor B1 T29C polymorphism and breast cancer risk in Japanese women. Breast Cancer (2003) 1.00
Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress. Am J Physiol Cell Physiol (2012) 1.00
Polymorphisms of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 and colorectal cancer risk in Chinese males. World J Gastroenterol (2008) 0.99
Indoxyl sulfate reduces superoxide scavenging activity in the kidneys of normal and uremic rats. Am J Nephrol (2007) 0.99
Methionine Synthase Reductase Gene A66G Polymorphism is Associated with Risk of Colorectal Cancer. Asian Pac J Cancer Prev (2002) 0.99
Cardiovascular disease mortality and serum carotenoid levels: a Japanese population-based follow-up study. J Epidemiol (2006) 0.98
Association between serum pepsinogens and polymorphismof PTPN11 encoding SHP-2 among Helicobacter pylori seropositive Japanese. Int J Cancer (2006) 0.98
Coronary artery calcification score is associated with mortality in Japanese hemodialysis patients. J Ren Nutr (2012) 0.98
KLOTHO gene polymorphisms G-395A and C1818T are associated with lipid and glucose metabolism, bone mineral density and systolic blood pressure in Japanese healthy subjects. Clin Chim Acta (2009) 0.98
Toll-like receptor 4 +3725 G/C polymorphism, Helicobacter pylori seropositivity, and the risk of gastric atrophy and gastric cancer in Japanese. Helicobacter (2009) 0.97
Sirtuin 1 gene polymorphisms are associated with body fat and blood pressure in Japanese. Transl Res (2011) 0.97
Dietary factors and the risk of gastric cancer among Japanese women: a comparison between the differentiated and non-differentiated subtypes. Ann Epidemiol (2003) 0.97
Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition. J Biol Chem (2002) 0.97
Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma. Am J Hematol (2004) 0.96
Indoxyl sulfate upregulates renal expression of MCP-1 via production of ROS and activation of NF-κB, p53, ERK, and JNK in proximal tubular cells. Life Sci (2012) 0.96
Combined effect of miR-146a rs2910164 G/C polymorphism and Toll-like receptor 4 +3725 G/C polymorphism on the risk of severe gastric atrophy in Japanese. Dig Dis Sci (2010) 0.96
Common variant of leucine-rich repeat-containing 16A (LRRC16A) gene is associated with gout susceptibility. Hum Cell (2013) 0.96
Healthcare waste management in the capital city of Mongolia. Waste Manag (2007) 0.96
Beneficial effects of Bifidobacteria in a gastroresistant seamless capsule on hyperhomocysteinemia in hemodialysis patients. J Ren Nutr (2005) 0.96
Genetic polymorphisms of TGF-beta1 & TNF-beta and breast cancer risk. Breast Cancer Res Treat (2005) 0.95
Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-ĸB. Am J Nephrol (2011) 0.95
Controls for monitoring the deterioration of stored blood samples in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study). Nagoya J Med Sci (2008) 0.95
Association of gene polymorphisms with intervertebral disc degeneration and vertebral osteophyte formation. Spine (Phila Pa 1976) (2007) 0.95
Genetic polymorphisms of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro and the risk of cervical cancer in Japanese. Cancer Lett (2004) 0.95
Interleukin-2 gene polymorphisms associated with increased risk of gastric atrophy from Helicobacter pylori infection. Helicobacter (2005) 0.94
Indoxyl sulfate reduces klotho expression and promotes senescence in the kidneys of hypertensive rats. J Ren Nutr (2011) 0.94
Consumption of soy foods and the risk of breast cancer: findings from the Japan Collaborative Cohort (JACC) Study. Cancer Causes Control (2007) 0.94
Dietary factors protective against breast cancer in Japanese premenopausal and postmenopausal women. Int J Cancer (2003) 0.94
Efficacy of genotype notification to Japanese smokers on smoking cessation--an intervention study at workplace. Cancer Epidemiol (2009) 0.94
A population-based follow-up study on mortality from cancer or cardiovascular disease and serum carotenoids, retinol and tocopherols in Japanese inhabitants. Asian Pac J Cancer Prev (2007) 0.93
Adjacent Segment Disease After Posterior Lumbar Interbody Fusion: Based on Cases With a Minimum of 10 Years of Follow-up. Spine (Phila Pa 1976) (2015) 0.93
Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development. Pharmacogenetics (2003) 0.93
Duplex polymerase chain reaction with confronting two-pair primers (PCR-CTPP) for genotyping alcohol dehydrogenase beta subunit (ADH2) and aldehyde dehydrogenase 2 (ALDH2). Alcohol Alcohol (2003) 0.93
Increased levels of advanced glycation end products in human cataractous lenses. J Cataract Refract Surg (2003) 0.93
Effects of dental treatment on the quality of life and activities of daily living in institutionalized elderly in Japan. Arch Gerontol Geriatr (2009) 0.93
Senescence and dysfunction of proximal tubular cells are associated with activated p53 expression by indoxyl sulfate. Am J Physiol Cell Physiol (2010) 0.92
Polymorphism in resistin promoter region at -420 determines the serum resistin levels and may be a risk marker of stroke in Japanese type 2 diabetic patients. Diabetes Res Clin Pract (2009) 0.92
Quantum dots for labeling adipose tissue-derived stem cells. Cell Transplant (2009) 0.92
AST-120 ameliorates epithelial-to-mesenchymal transition and interstitial fibrosis in the kidneys of chronic kidney disease rats. J Ren Nutr (2012) 0.92
A pilot study to evaluate stomach cancer risk reduction by Helicobacter pylori eradication. Am J Gastroenterol (2002) 0.92
An oral sorbent, AST-120, increases Klotho expression and inhibits cell senescence in the kidney of uremic rats. Am J Nephrol (2009) 0.92
C9-R95X polymorphism in patients with neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci (2012) 0.92
Report of the Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer. Cancer Sci (2013) 0.91
Indoxyl sulfate and atherosclerotic risk factors in hemodialysis patients. Am J Nephrol (2007) 0.91
hOGG1 Ser326Cys polymorphism and breast cancer risk among Asian women. Breast Cancer Res Treat (2003) 0.91
Association of transporter associated with antigen processing (TAP) gene polymorphisms in donors with acute cellular rejection in living donor liver transplantation. J Gastrointestin Liver Dis (2013) 0.91
Advanced glycation end-products and peritoneal sclerosis. Semin Nephrol (2004) 0.91