Published in PLoS One on August 18, 2014
Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell (2002) 3.28
The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways. Cell (1985) 3.28
The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus. Mol Cell Biol (1987) 2.30
Identification and characterization of the human ARD1-NATH protein acetyltransferase complex. Biochem J (2005) 1.96
Human arrest defective 1 acetylates and activates beta-catenin, promoting lung cancer cell proliferation. Cancer Res (2006) 1.53
Inactivation of androgen-induced regulator ARD1 inhibits androgen receptor acetylation and prostate tumorigenesis. Proc Natl Acad Sci U S A (2012) 1.52
Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF. J Biol Chem (2005) 1.38
An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development. J Biol Chem (2003) 1.29
ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Sci Signal (2010) 1.22
N-acetyltransferase ARD1-NAT1 regulates neuronal dendritic development. Genes Cells (2008) 1.19
N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity. Cancer Cell (2011) 1.17
Molecular basis for N-terminal acetylation by the heterodimeric NatA complex. Nat Struct Mol Biol (2013) 1.16
Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms. Thyroid (2005) 1.07
Characterization of ARD1 variants in mammalian cells. Biochem Biophys Res Commun (2005) 1.01
Arrest defective 1 autoacetylation is a critical step in its ability to stimulate cancer cell proliferation. Cancer Res (2010) 0.97
Arrest-defective-1 protein (ARD1): tumor suppressor or oncoprotein? Am J Transl Res (2010) 0.95
Correlation of expression of human arrest-defective-1 (hARD1) protein with breast cancer. Cancer Invest (2009) 0.92
Up-regulation of human arrest-defective 1 protein is correlated with metastatic phenotype and poor prognosis in breast cancer. Asian Pac J Cancer Prev (2011) 0.86
ARD1 binding to RIP1 mediates doxorubicin-induced NF-κB activation. Biochem Biophys Res Commun (2012) 0.84
Roles of arrest-defective protein 1(225) and hypoxia-inducible factor 1alpha in tumor growth and metastasis. J Natl Cancer Inst (2010) 0.84
Differential regulation of splicing, localization and stability of mammalian ARD1235 and ARD1225 isoforms. Biochem Biophys Res Commun (2006) 0.84
N-α-acetyltransferase 10 protein inhibits apoptosis through RelA/p65-regulated MCL1 expression. Carcinogenesis (2012) 0.82
Oligodendrocyte precursor cells support blood-brain barrier integrity via TGF-β signaling. PLoS One (2014) 0.89
AKAP12 mediates barrier functions of fibrotic scars during CNS repair. PLoS One (2014) 0.85