Published in Philos Trans R Soc Lond B Biol Sci on September 26, 2014
Biological properties of extracellular vesicles and their physiological functions. J Extracell Vesicles (2015) 3.02
Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. J Extracell Vesicles (2015) 1.30
Emerging roles of extracellular vesicles in the nervous system. J Neurosci (2014) 1.09
Extracellular vesicles round off communication in the nervous system. Nat Rev Neurosci (2016) 1.04
Neuroinflammation and Depression: Microglia Activation, Extracellular Microvesicles and microRNA Dysregulation. Front Cell Neurosci (2015) 0.97
Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons. J Extracell Vesicles (2014) 0.94
Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation. Acta Neuropathol (2015) 0.90
Extracellular vesicles and intercellular communication within the nervous system. J Clin Invest (2016) 0.87
Extracellular Vesicles and a Novel Form of Communication in the Brain. Front Neurosci (2016) 0.86
Extracellular Vesicles: Unique Intercellular Delivery Vehicles. Trends Cell Biol (2016) 0.85
Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche. Stem Cells Int (2016) 0.85
Focus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's Disease. Int J Mol Sci (2016) 0.84
Exosomes in stroke pathogenesis and therapy. J Clin Invest (2016) 0.84
Extracellular Membrane Vesicles as Vehicles for Brain Cell-to-Cell Interactions in Physiological as well as Pathological Conditions. Biomed Res Int (2015) 0.80
Schwann Cell Exosomes Mediate Neuron-Glia Communication and Enhance Axonal Regeneration. Cell Mol Neurobiol (2016) 0.80
Exosomes: The Messengers of Health and Disease. Curr Neuropharmacol (2016) 0.80
Exosomes as Novel Regulators of Adult Neurogenic Niches. Front Cell Neurosci (2016) 0.78
Regulation of neuronal excitability by release of proteins from glial cells. Philos Trans R Soc Lond B Biol Sci (2015) 0.78
The role of exosomes in the pathogenesis of Alzheimer' disease. Transl Neurodegener (2017) 0.78
Modulation of cellular function through immune-activated exosomes. DNA Cell Biol (2015) 0.77
Axonal maintenance, glia, exosomes, and heat shock proteins. F1000Res (2016) 0.76
Potential Modes of Intercellular α-Synuclein Transmission. Int J Mol Sci (2017) 0.76
Acellular approaches for regenerative medicine: on the verge of clinical trials with extracellular membrane vesicles? Stem Cell Res Ther (2015) 0.76
Local translation in neuronal compartments: how local is local? EMBO Rep (2017) 0.75
Exosomes and the Prion Protein: More than One Truth. Front Neurosci (2017) 0.75
Introduction. Philos Trans R Soc Lond B Biol Sci (2014) 0.75
Turing Revisited: Decoding the microRNA Messages in Brain Extracellular Vesicles for Early Detection of Neurodevelopmental Disorders. Curr Environ Health Rep (2016) 0.75
Port-to-port delivery: Mobilization of toxic sphingolipids via extracellular vesicles. J Neurosci Res (2016) 0.75
Evaluation of amniotic mesenchymal cell derivatives on cytokine production in equine alveolar macrophages: an in vitro approach to lung inflammation. Stem Cell Res Ther (2016) 0.75
Bioconductor: open software development for computational biology and bioinformatics. Genome Biol (2004) 143.19
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol (2007) 37.10
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol (2008) 19.86
Membrane vesicles as conveyors of immune responses. Nat Rev Immunol (2009) 14.72
Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science (1997) 11.48
GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci (2003) 10.89
Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol (2013) 10.02
Function and regulation of CREB family transcription factors in the nervous system. Neuron (2002) 7.99
Functional delivery of viral miRNAs via exosomes. Proc Natl Acad Sci U S A (2010) 6.72
Secreted monocytic miR-150 enhances targeted endothelial cell migration. Mol Cell (2010) 5.77
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev (1997) 5.58
Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron (1998) 5.05
JNK signaling in apoptosis. Oncogene (2008) 4.72
CREB is a regulatory target for the protein kinase Akt/PKB. J Biol Chem (1998) 4.12
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles (2013) 4.05
Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry (2003) 3.12
Exosomes are released by cultured cortical neurones. Mol Cell Neurosci (2006) 3.07
As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles (2013) 3.01
Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes. J Neurosci (2008) 2.95
Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation. J Neurosci (2007) 2.69
Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats. Exp Neurol (2005) 2.69
Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. Oncogene (1999) 2.66
Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol (2013) 2.61
The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB. Mol Brain (2012) 2.43
Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes. Nat Genet (2007) 2.30
Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis. J Cell Sci (2011) 2.25
Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. J Neurosci (1993) 2.23
Activated c-Jun N-terminal kinase is required for axon formation. J Neurosci (2006) 2.22
Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity. Mol Cell Neurosci (2010) 2.17
In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance. Brain Res (2001) 2.07
Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain. Nat Neurosci (2013) 1.98
The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron (2000) 1.95
Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. PLoS One (2010) 1.94
Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice. Neuroscience (2003) 1.80
A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons. Mol Cell (2006) 1.75
Exosomes: small vesicles participating in intercellular communication. Int J Biochem Cell Biol (2011) 1.68
Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases? Front Physiol (2012) 1.65
Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity. J Neurosci (2003) 1.64
Heat shock proteins and protection of the nervous system. Ann N Y Acad Sci (2007) 1.62
CREB: a multifaceted regulator of neuronal plasticity and protection. J Neurochem (2010) 1.58
Coupling gene expression to cAMP signalling: role of CREB and CREM. Int J Biochem Cell Biol (1998) 1.52
Is CREB a key to neuronal survival? Trends Neurosci (2000) 1.48
Evidence for secretion of Cu,Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis. Neurosci Lett (2007) 1.41
Doublecortin, a stabilizer of microtubules. Hum Mol Genet (1999) 1.41
The neuropeptide VGF produces antidepressant-like behavioral effects and enhances proliferation in the hippocampus. J Neurosci (2007) 1.34
Exosomes: vesicular carriers for intercellular communication in neurodegenerative disorders. Cell Tissue Res (2012) 1.31
Exosome formation during maturation of mammalian and avian reticulocytes: evidence that exosome release is a major route for externalization of obsolete membrane proteins. J Cell Physiol (1991) 1.31
Heat shock-like protein is transferred from glia to axon. Brain Res (1986) 1.30
Inhibition of myelin membrane sheath formation by oligodendrocyte-derived exosome-like vesicles. J Biol Chem (2010) 1.29
Schwann cell-derived exosomes enhance axonal regeneration in the peripheral nervous system. Glia (2013) 1.29
Role of the immediate early response 3 (IER3) gene in cellular stress response, inflammation and tumorigenesis. Eur J Cell Biol (2010) 1.28
Regulation of heat shock protein 70 release in astrocytes: role of signaling kinases. Dev Neurobiol (2007) 1.28
Emerging role of neuronal exosomes in the central nervous system. Front Physiol (2012) 1.25
Inhibition of GSK3beta is a common event in neuroprotection by different survival factors. Brain Res Mol Brain Res (2005) 1.24
Oligodendrocytes direct glycosyl phosphatidylinositol-anchored proteins to the myelin sheath in glycosphingolipid-rich complexes. J Biol Chem (1997) 1.22
Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism. EMBO J (2012) 1.16
The neurotrophin-inducible gene Vgf regulates hippocampal function and behavior through a brain-derived neurotrophic factor-dependent mechanism. J Neurosci (2008) 1.13
Hypoxia activates Akt and induces phosphorylation of GSK-3 in PC12 cells. Cell Signal (2001) 1.11
Self-organization of repetitive spike patterns in developing neuronal networks in vitro. Eur J Neurosci (2010) 1.10
Extracellular vesicles as mediators of neuron-glia communication. Front Cell Neurosci (2013) 1.08
Release of heat shock proteins (Hsps) and the effects of extracellular Hsps on neural cells and tissues. Int J Hyperthermia (2005) 1.04
MEK and ERK protect hypoxic cortical neurons via phosphorylation of Bad. J Neurochem (2002) 1.02
Concurrent assessment of calpain and caspase-3 activation after oxygen-glucose deprivation in primary septo-hippocampal cultures. J Cereb Blood Flow Metab (2001) 0.97
Genetic approaches to investigate the role of CREB in neuronal plasticity and memory. Mol Neurobiol (2011) 0.97
Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7. J Neurosci (2011) 0.92
Inhibition of glutamate release via recovery of ATP levels accounts for a neuroprotective effect of aspirin in rat cortical neurons exposed to oxygen-glucose deprivation. Stroke (2002) 0.90
LPS-induced microglial secretion of TNFα increases activity-dependent neuronal apoptosis in the neonatal cerebral cortex. Cereb Cortex (2012) 0.89
Changes in the expression of transcription factors ATF-2 and Fra-2 after axotomy and during regeneration in rat retinal ganglion cells. Brain Res Mol Brain Res (1996) 0.79
Co-expression of c-Jun and ATF-2 characterizes the surviving retinal ganglion cells which maintain axonal connections after partial optic nerve injury. Brain Res Mol Brain Res (1999) 0.78