Published in J Pharm Sci on August 29, 2014
Human renal organic anion transporter 4 operates as an asymmetric urate transporter. J Am Soc Nephrol (2007) 1.60
Organic anion transporters of the SLC22 family: biopharmaceutical, physiological, and pathological roles. Pharm Res (2007) 1.55
Glyoxylate is a substrate of the sulfate-oxalate exchanger, sat-1, and increases its expression in HepG2 cells. J Hepatol (2010) 1.47
Rat renal cortical OAT1 and OAT3 exhibit gender differences determined by both androgen stimulation and estrogen inhibition. Am J Physiol Renal Physiol (2004) 1.43
Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13). J Biol Chem (2008) 1.26
Gender differences in kidney function. Pflugers Arch (2007) 1.14
Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux. Cell Physiol Biochem (2003) 1.14
Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites. Am J Physiol Cell Physiol (2005) 1.07
Protein kinase C activation downregulates human organic anion transporter 1-mediated transport through carrier internalization. J Am Soc Nephrol (2003) 1.06
Acute regulation of Na/H exchanger NHE3 by adenosine A(1) receptors is mediated by calcineurin homologous protein. J Biol Chem (2003) 1.00
NH(4)(+) conductance in Xenopus laevis oocytes. III. Effect of NH(3). Pflugers Arch (2003) 1.00
Mutational analysis of the ABCC6 gene and the proximal ABCC6 gene promoter in German patients with pseudoxanthoma elasticum (PXE). Hum Mutat (2006) 0.99
Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy. Toxicology (2009) 0.98
Localization of the sulfate/anion exchanger in the rat liver. Am J Physiol Gastrointest Liver Physiol (2005) 0.97
Ability of sat-1 to transport sulfate, bicarbonate, or oxalate under physiological conditions. Am J Physiol Renal Physiol (2009) 0.97
The renal Na(+)-dependent dicarboxylate transporter, NaDC-3, translocates dimethyl- and disulfhydryl-compounds and contributes to renal heavy metal detoxification. J Am Soc Nephrol (2002) 0.97
Substrate specificity of the human renal sodium dicarboxylate cotransporter, hNaDC-3, under voltage-clamp conditions. Am J Physiol Renal Physiol (2004) 0.95
Torsemide renal clearance and genetic variation in luminal and basolateral organic anion transporters. Br J Clin Pharmacol (2006) 0.95
Human organic cation transporter 1 is expressed in lymphoma cells and increases susceptibility to irinotecan and paclitaxel. J Pharmacol Exp Ther (2011) 0.92
Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones. Am J Physiol Renal Physiol (2006) 0.92
The chloride dependence of the human organic anion transporter 1 (hOAT1) is blunted by mutation of a single amino acid. J Biol Chem (2007) 0.91
Piloting an outcome-based programme evaluation tool in undergraduate medical education. GMS Z Med Ausbild (2012) 0.91
Bimodal acute effects of A1 adenosine receptor activation on Na+/H+ exchanger 3 in opossum kidney cells. J Am Soc Nephrol (2003) 0.90
Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines. Biochem Pharmacol (2009) 0.90
Differential interaction of dicarboxylates with human sodium-dicarboxylate cotransporter 3 and organic anion transporters 1 and 3. Am J Physiol Renal Physiol (2011) 0.90
New clues for nephrotoxicity induced by ifosfamide: preferential renal uptake via the human organic cation transporter 2. Mol Pharm (2010) 0.89
Expression of human organic cation transporter 3 in kidney carcinoma cell lines increases chemosensitivity to melphalan, irinotecan, and vincristine. Cancer Res (2009) 0.89
Relative contribution of OAT and OCT transporters to organic electrolyte transport in rabbit proximal tubule. Am J Physiol Renal Physiol (2004) 0.88
URAT1 mutations cause renal hypouricemia type 1 in Iraqi Jews. Nephrol Dial Transplant (2010) 0.87
Presence of organic anion transporters 3 (OAT3) and 4 (OAT4) in human adrenocortical cells. Pflugers Arch (2004) 0.86
Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias. Pflugers Arch (2008) 0.85
Interactions of benzylpenicillin and non-steroidal anti-inflammatory drugs with the sodium-dependent dicarboxylate transporter NaDC-3. Cell Physiol Biochem (2004) 0.84
Torasemide transport by organic anion transporters contributes to hyperuricemia. J Am Soc Nephrol (2007) 0.84
The liver and kidney expression of sulfate anion transporter sat-1 in rats exhibits male-dominant gender differences. Pflugers Arch (2008) 0.83
The sodium-dependent di- and tricarboxylate transporter, NaCT, is not responsible for the uptake of D-, L-2-hydroxyglutarate and 3-hydroxyglutarate into neurons. J Inherit Metab Dis (2011) 0.83
Transport of cimetidine by flounder and human renal organic anion transporter 1. Am J Physiol Renal Physiol (2002) 0.82
Short- and long-term A3 adenosine receptor activation inhibits the Na+/H+ exchanger NHE3 activity and expression in opossum kidney cells. J Cell Physiol (2008) 0.82
Mycophenolic acid (MPA) and its glucuronide metabolites interact with transport systems responsible for excretion of organic anions in the basolateral membrane of the human kidney. Nephrol Dial Transplant (2007) 0.82
Molecular aspects of acute inhibition of Na(+)-H(+) exchanger NHE3 by A(2)-adenosine receptor agonists. J Physiol (2002) 0.82
Expression studies and functional characterization of renal human organic anion transporter 1 isoforms. Drug Metab Dispos (2004) 0.81
Organic anion transporter 3 (OAT3) and renal transport of the metal chelator 2,3-dimercapto-1-propanesulfonic acid (DMPS). Can J Physiol Pharmacol (2010) 0.81
Regulation of sodium-dicarboxylate cotransporter-3 from winter flounder kidney by protein kinase C. Am J Physiol Renal Physiol (2003) 0.81
Uptake of chemically reactive, DNA-damaging sulfuric acid esters into renal cells by human organic anion transporters. J Am Soc Nephrol (2006) 0.80
Cloning of the pig renal organic anion transporter 1 (pOAT1). Biochimie (2002) 0.79
RT-PCR-based evidence for the in vivo stimulation of renal tubularp-aminohippurate (PAH) transport by triiodothyronine (T3) or dexamethasone (DEXA) in kidney tissue of immature and adult rats. Exp Toxicol Pathol (2003) 0.79
Glutathione is a low-affinity substrate of the human sodium-dependent dicarboxylate transporter. Nephron Physiol (2013) 0.79
Regulation of steroid hormone biosynthesis enzymes and organic anion transporters by forskolin and DHEA-S treatment in adrenocortical cells. Am J Physiol Endocrinol Metab (2006) 0.79
Tripeptides of RS1 (RSC1A1) inhibit a monosaccharide-dependent exocytotic pathway of Na+-D-glucose cotransporter SGLT1 with high affinity. J Biol Chem (2007) 0.79
Pharmacogenomics of diuretic drugs: data on rare monogenic disorders and on polymorphisms and requirements for further research. Pharmacogenomics (2003) 0.79
Oxalate: from the environment to kidney stones. Arh Hig Rada Toksikol (2013) 0.78
On a fully closed state of native human type-1 VDAC enriched in Nonidet P40. Mol Genet Metab (2012) 0.78
3-Hydroxyglutaric acid is transported via the sodium-dependent dicarboxylate transporter NaDC3. J Mol Med (Berl) (2007) 0.77
Basolateral localization of flounder Na+-dicarboxylate cotransporter (fNaDC-3) in the kidney of Pleuronectes americanus. Pflugers Arch (2003) 0.77
Functional expression of pig renal organic anion transporter 3 (pOAT3). Biochimie (2005) 0.77
[A contribution to the needs assessment of faculty development measures in medical schools]. Med Klin (Munich) (2009) 0.77
Interaction of cysteine conjugates with human and rabbit organic anion transporter 1. J Pharmacol Exp Ther (2003) 0.76
Immunocytochemical characterization of the incubated rat renal cortical slices. Pflugers Arch (2005) 0.76
Male-dominant activation of rat renal organic anion transporter 1 (Oat1) and 3 (Oat3) expression by transcription factor BCL6. PLoS One (2012) 0.76
In female rats, ethylene glycol treatment elevates protein expression of hepatic and renal oxalate transporter sat-1 (Slc26a1) without inducing hyperoxaluria. Croat Med J (2015) 0.76
SLC22 transporter family proteins as targets for cytostatic uptake into tumor cells. Biol Chem (2011) 0.76
Interaction of human multidrug and toxin extrusion 1 (MATE1) transporter with antineoplastic agents. Drug Metabol Drug Interact (2011) 0.76
Functional roles of cationic amino acid residues in the sodium-dicarboxylate cotransporter 3 (NaDC-3) from winter flounder. Am J Physiol Renal Physiol (2006) 0.75
AAV-mediated gene therapy for metabolic diseases: dosage and reapplication studies in the molybdenum cofactor deficiency model. Genet Vaccines Ther (2009) 0.75
Human organic anion transporter OAT1 is not responsible for glutathione transport but mediates transport of glutamate derivatives. Am J Physiol Renal Physiol (2012) 0.75
Professor Karl Julius Ullrich--in memoriam. Kidney Int (2010) 0.75
α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4). Pflugers Arch (2012) 0.75
Interaction of Excitatory Amino Acid Transporters 1 - 3 (EAAT1, EAAT2, EAAT3) with N-Carbamoylglutamate and N-Acetylglutamate. Cell Physiol Biochem (2017) 0.75
A multi-faceted world of transporters. Naunyn Schmiedebergs Arch Pharmacol (2006) 0.75
Mutation of amino acid 475 of rat organic cation transporter 2 (rOCT2) impairs organic cation transport. Biochimie (2004) 0.75
The Isoquinolone Derived Prolyl Hydroxylase Inhibitor ICA Is a Potent Substrate of the Organic Anion Transporters 1 and 3. Nephron (2015) 0.75