Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.

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Published in Cell Rep on September 18, 2014

Authors

Anetta Ptasinska1, Salam A Assi2, Natalia Martinez-Soria3, Maria Rosaria Imperato1, Jason Piper4, Pierre Cauchy1, Anna Pickin1, Sally R James5, Maarten Hoogenkamp1, Dan Williamson3, Mengchu Wu6, Daniel G Tenen6, Sascha Ott4, David R Westhead7, Peter N Cockerill1, Olaf Heidenreich8, Constanze Bonifer9

Author Affiliations

1: School of Cancer Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham B15 2TT, UK.
2: School of Cancer Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham B15 2TT, UK; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
3: Northern Institute for Cancer Research, University of Newcastle, Newcastle upon Tyne NE2 4HH, UK.
4: Warwick Systems Biology Centre, University of Warwick, Coventry CV4 7AL, UK.
5: Section of Experimental Haematology, Leeds Institute for Molecular Medicine, University of Leeds, Leeds LS2 9JT, UK.
6: Cancer Science Institute, National University of Singapore, Republic of Singapore, Singapore 117456, Singapore.
7: School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.
8: Northern Institute for Cancer Research, University of Newcastle, Newcastle upon Tyne NE2 4HH, UK. Electronic address: olaf.heidenreich@ncl.ac.uk.
9: School of Cancer Sciences, College of Medicine and Dentistry, University of Birmingham, Birmingham B15 2TT, UK. Electronic address: c.bonifer@bham.ac.uk.

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