Published in Brain Behav Evol on September 20, 2014
Animal Models of Speech and Vocal Communication Deficits Associated With Psychiatric Disorders. Biol Psychiatry (2015) 0.79
Insights into the Neural and Genetic Basis of Vocal Communication. Cell (2016) 0.79
Sumoylation of FOXP2 Regulates Motor Function and Vocal Communication Through Purkinje Cell Development. Biol Psychiatry (2016) 0.77
Initial sequence of the chimpanzee genome and comparison with the human genome. Nature (2005) 25.67
Evolution at two levels in humans and chimpanzees. Science (1975) 21.07
A draft sequence of the Neandertal genome. Science (2010) 19.55
De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature (2012) 13.61
Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci (2006) 12.37
Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature (2011) 10.16
A forkhead-domain gene is mutated in a severe speech and language disorder. Nature (2001) 9.25
Spatio-temporal transcriptome of the human brain. Nature (2011) 9.19
Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature (2010) 8.99
Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP). Lancet (2006) 8.00
Functional organization of the transcriptome in human brain. Nat Neurosci (2008) 7.02
Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease. N Engl J Med (2014) 6.67
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med (2014) 6.50
A mesoscale connectome of the mouse brain. Nature (2014) 6.32
Molecular evolution of FOXP2, a gene involved in speech and language. Nature (2002) 5.89
Conservation and evolution of gene coexpression networks in human and chimpanzee brains. Proc Natl Acad Sci U S A (2006) 5.69
Functional and evolutionary insights into human brain development through global transcriptome analysis. Neuron (2009) 5.46
Epidemiology of autistic disorder and other pervasive developmental disorders. J Clin Psychiatry (2005) 5.30
Behavioural phenotyping assays for mouse models of autism. Nat Rev Neurosci (2010) 5.27
Pervasive developmental disorders in preschool children. JAMA (2001) 5.13
Neurogenic radial glia in the outer subventricular zone of human neocortex. Nature (2010) 5.10
A functional genetic link between distinct developmental language disorders. N Engl J Med (2008) 4.99
Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science (2006) 4.68
Global prevalence of autism and other pervasive developmental disorders. Autism Res (2012) 4.62
The autistic neuron: troubled translation? Cell (2008) 3.81
A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell (2009) 3.63
The derived FOXP2 variant of modern humans was shared with Neandertals. Curr Biol (2007) 3.39
The brain reward circuitry in mood disorders. Nat Rev Neurosci (2013) 3.08
Evolution of primate gene expression. Nat Rev Genet (2006) 3.04
Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain. J Comp Neurol (2003) 3.01
A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging. J Neurosci (2008) 2.97
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell (2013) 2.94
Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell (2013) 2.87
Genetic architecture in autism spectrum disorder. Curr Opin Genet Dev (2012) 2.86
Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways. Proc Natl Acad Sci U S A (2010) 2.85
Human-specific transcriptional networks in the brain. Neuron (2012) 2.80
Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene. Proc Natl Acad Sci U S A (2005) 2.76
FOXP2 and the neuroanatomy of speech and language. Nat Rev Neurosci (2005) 2.68
Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions. Mol Cell Biol (2004) 2.48
Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication. Cell (2012) 2.43
Human brain evolution: insights from microarrays. Nat Rev Genet (2004) 2.42
SRPX2 mutations in disorders of language cortex and cognition. Hum Mol Genet (2006) 2.34
Human-specific transcriptional regulation of CNS development genes by FOXP2. Nature (2009) 2.33
Differential L1 regulation in pluripotent stem cells of humans and apes. Nature (2013) 2.29
A de novo convergence of autism genetics and molecular neuroscience. Trends Neurosci (2013) 2.24
A neurocognitive perspective on language: the declarative/procedural model. Nat Rev Neurosci (2001) 2.16
Key role for gene dosage and synaptic homeostasis in autism spectrum disorders. Trends Genet (2010) 2.14
Sex differences in autism spectrum disorders. Curr Opin Neurol (2013) 2.11
Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain. Am J Hum Genet (2007) 2.08
Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation. Cell (2012) 2.02
Comparing the human and chimpanzee genomes: searching for needles in a haystack. Genome Res (2005) 1.95
The prevalence and epidemiology of Gilles de la Tourette syndrome. Part 1: the epidemiological and prevalence studies. J Psychosom Res (2008) 1.88
Age-related dendritic and spine changes in corticocortically projecting neurons in macaque monkeys. Cereb Cortex (2003) 1.83
Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia. Genome Res (2010) 1.83
The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans. Brain Struct Funct (2010) 1.71
The pyramidal cell in cognition: a comparative study in human and monkey. J Neurosci (2001) 1.71
Autism genetics: searching for specificity and convergence. Genome Biol (2012) 1.70
The human language-associated gene SRPX2 regulates synapse formation and vocalization in mice. Science (2013) 1.64
Adaptive evolution of genes underlying schizophrenia. Proc Biol Sci (2007) 1.58
Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain. PLoS Genet (2011) 1.56
Is schizophrenia on the autism spectrum? Brain Res (2010) 1.54
Deciphering the genetic basis of speech and language disorders. Annu Rev Neurosci (2003) 1.53
Schizophrenia as the price that homo sapiens pays for language: a resolution of the central paradox in the origin of the species. Brain Res Brain Res Rev (2000) 1.52
Evolution of genetic and genomic features unique to the human lineage. Nat Rev Genet (2012) 1.44
Spatial organization of neurons in the frontal pole sets humans apart from great apes. Cereb Cortex (2010) 1.42
The evolution of distributed association networks in the human brain. Trends Cogn Sci (2013) 1.40
Accelerated recruitment of new brain development genes into the human genome. PLoS Biol (2011) 1.39
Specific role of VTA dopamine neuronal firing rates and morphology in the reversal of anxiety-related, but not depression-related behavior in the ClockΔ19 mouse model of mania. Neuropsychopharmacology (2011) 1.37
The 'big bang' theory of the origin of psychosis and the faculty of language. Schizophr Res (2008) 1.36
Accelerated FoxP2 evolution in echolocating bats. PLoS One (2007) 1.34
Density and morphology of dendritic spines in mouse neocortex. Neuroscience (2006) 1.34
Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling. Neuron (2011) 1.34
Weighted gene coexpression network analysis: state of the art. J Biopharm Stat (2010) 1.32
Temporal specification and bilaterality of human neocortical topographic gene expression. Neuron (2013) 1.26
FOXP2 in focus: what can genes tell us about speech and language? Trends Cogn Sci (2003) 1.22
Autism spectrum disorder diagnoses in Stockholm preschoolers. Res Dev Disabil (2010) 1.21
DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics. Mol Autism (2014) 1.20
Human prefrontal cortex: evolution, development, and pathology. Prog Brain Res (2012) 1.19
Molecular networks implicated in speech-related disorders: FOXP2 regulates the SRPX2/uPAR complex. Hum Mol Genet (2010) 1.17
Modeling the functional genomics of autism using human neurons. Mol Psychiatry (2011) 1.17
Human brain evolution: transcripts, metabolites and their regulators. Nat Rev Neurosci (2013) 1.16
Two gene co-expression modules differentiate psychotics and controls. Mol Psychiatry (2012) 1.15
Diminished FoxP2 levels affect dopaminergic modulation of corticostriatal signaling important to song variability. Neuron (2013) 1.14
Development of rostral prefrontal cortex and cognitive and behavioural disorders. Dev Med Child Neurol (2008) 1.13
A recent evolutionary change affects a regulatory element in the human FOXP2 gene. Mol Biol Evol (2012) 1.08
The distinct and overlapping phenotypic spectra of FOXP1 and FOXP2 in cognitive disorders. Hum Genet (2012) 1.08
Regulation of MET by FOXP2, genes implicated in higher cognitive dysfunction and autism risk. J Neurosci (2011) 1.07
Translational animal models of autism and neurodevelopmental disorders. Dialogues Clin Neurosci (2012) 1.06
Autism spectrum disorder and the cerebellum. Int Rev Neurobiol (2013) 1.05
The developmental transcriptome of the human brain: implications for neurodevelopmental disorders. Curr Opin Neurol (2014) 1.04
Conservation and diversity of Foxp2 expression in muroid rodents: functional implications. J Comp Neurol (2009) 1.04
Affiliation, empathy, and the origins of theory of mind. Proc Natl Acad Sci U S A (2013) 1.03
"Seq-ing" insights into the epigenetics of neuronal gene regulation. Neuron (2013) 1.03
A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples. Arch Gen Psychiatry (2012) 1.02
Basal ganglia and language: phonology modulates dopaminergic release. Neuroreport (2005) 1.01
FoxP2 regulates neurogenesis during embryonic cortical development. J Neurosci (2013) 1.01
Dendritic morphology of pyramidal neurons in the chimpanzee neocortex: regional specializations and comparison to humans. Cereb Cortex (2012) 1.00
Human brain evolution: harnessing the genomics (r)evolution to link genes, cognition, and behavior. Neuron (2010) 0.99
When brain clocks lose track of time: cause or consequence of neuropsychiatric disorders. Curr Opin Neurobiol (2011) 0.97
Developmental origins of brain disorders: roles for dopamine. Front Cell Neurosci (2013) 0.94
Functional organization of the transcriptome in human brain. Nat Neurosci (2008) 7.02
Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev (2008) 2.61
Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc Natl Acad Sci U S A (2006) 2.25
Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain. Am J Hum Genet (2007) 2.08
Neuroscience in the era of functional genomics and systems biology. Nature (2009) 1.80
RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. Hum Mol Genet (2012) 1.51
HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells. Development (2011) 1.50
Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness. J Neurosci (2008) 1.36
Divergent whole-genome methylation maps of human and chimpanzee brains reveal epigenetic basis of human regulatory evolution. Am J Hum Genet (2012) 1.31
Regulation of MET by FOXP2, genes implicated in higher cognitive dysfunction and autism risk. J Neurosci (2011) 1.07
STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation. J Neurosci (2012) 0.87
The role of the FOXP family of transcription factors in ASD. Dis Markers (2012) 0.83
Lens epithelium-derived growth factor (LEDGF/p75) expression in fetal and adult human brain. Exp Eye Res (2004) 0.83
Connecting signaling pathways underlying communication to ASD vulnerability. Int Rev Neurobiol (2013) 0.79
Neuroscience: Genes and human brain evolution. Nature (2012) 0.79
Influencing circadian and sleep-wake regulation for prevention and intervention in mood and anxiety disorders: what makes a good homeostat? Ann N Y Acad Sci (2014) 0.77
Decoding human gene expression signatures in the brain. Transcription (2013) 0.76
Differential functional constraints on the evolution of postsynaptic density proteins in neocortical laminae. PLoS One (2012) 0.75