Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse.

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Published in PLoS Biol on September 23, 2014

Authors

Brooke Tata1, Lukas Huijbregts1, Sandrine Jacquier2, Zsolt Csaba2, Emmanuelle Genin3, Vincent Meyer4, Sofia Leka2, Joelle Dupont5, Perrine Charles6, Didier Chevenne7, Jean-Claude Carel8, Juliane Léger8, Nicolas de Roux9

Author Affiliations

1: Inserm, U1141, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Hôpital Robert Debré, Paris, France.
2: Inserm, U1141, Paris, France.
3: Inserm, U1078, Brest, France.
4: Genoscope, IG-DSV-CEA, Evry, France.
5: INRA, UMR85 Physiologie de la Reproduction et des Comportements, Nouzilly, France.
6: Genetics Department and Inserm US975, Université Pierre et Marie Curie, Hôpital la Pitié-Salpêtrière, Paris, France.
7: AP-HP, Laboratoire de Biochimie, Hôpital Robert Debré, Paris, France.
8: Inserm, U1141, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Hôpital Robert Debré, Paris, France; AP-HP, Service d'Endocrinologie Diabétologie Pédiatrique et Centre de Référence des Maladies Endocriniennes Rares de la Croissance, Hôpital Robert Debré, Paris, France.
9: Inserm, U1141, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Hôpital Robert Debré, Paris, France; AP-HP, Laboratoire de Biochimie, Hôpital Robert Debré, Paris, France.

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