Karl E Kadler

Author PubWeight™ 54.14‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Procollagen trafficking, processing and fibrillogenesis. J Cell Sci 2005 3.54
2 Coalignment of plasma membrane channels and protrusions (fibripositors) specifies the parallelism of tendon. J Cell Biol 2004 2.19
3 Transcription factor EGR1 directs tendon differentiation and promotes tendon repair. J Clin Invest 2013 1.79
4 Actin filaments are required for fibripositor-mediated collagen fibril alignment in tendon. J Biol Chem 2006 1.39
5 Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP. Hum Mol Genet 2007 1.35
6 Tension is required for fibripositor formation. Matrix Biol 2008 1.35
7 Proteinases of the bone morphogenetic protein-1 family convert procollagen VII to mature anchoring fibril collagen. J Biol Chem 2002 1.32
8 Using transmission electron microscopy and 3View to determine collagen fibril size and three-dimensional organization. Nat Protoc 2013 1.31
9 Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo. Circ Res 2008 1.30
10 Age-related changes on the surface of vitreous collagen fibrils. Invest Ophthalmol Vis Sci 2004 1.22
11 Targeted induction of endoplasmic reticulum stress induces cartilage pathology. PLoS Genet 2009 1.21
12 Paired basic/Furin-like proprotein convertase cleavage of Pro-BMP-1 in the trans-Golgi network. J Biol Chem 2003 1.18
13 Decreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation. Hum Mol Genet 2007 1.18
14 The initiation of embryonic-like collagen fibrillogenesis by adult human tendon fibroblasts when cultured under tension. Biomaterials 2010 1.16
15 The cellular biology of flexor tendon adhesion formation: an old problem in a new paradigm. Am J Pathol 2009 1.13
16 The angiogenic inhibitor long pentraxin PTX3 forms an asymmetric octamer with two binding sites for FGF2. J Biol Chem 2010 1.13
17 The 10+4 microfibril structure of thin cartilage fibrils. Proc Natl Acad Sci U S A 2006 1.11
18 Collagen XXVII is developmentally regulated and forms thin fibrillar structures distinct from those of classical vertebrate fibrillar collagens. J Biol Chem 2007 1.10
19 Role of dimerization and substrate exclusion in the regulation of bone morphogenetic protein-1 and mammalian tolloid. Proc Natl Acad Sci U S A 2009 1.09
20 Temporal and spatial expression of collagens during murine atrioventricular heart valve development and maintenance. Dev Dyn 2008 1.04
21 Bone morphogenetic protein-1 (BMP-1). Identification of the minimal domain structure for procollagen C-proteinase activity. J Biol Chem 2003 1.04
22 Identification of the minimal domain structure of bone morphogenetic protein-1 (BMP-1) for chordinase activity: chordinase activity is not enhanced by procollagen C-proteinase enhancer-1 (PCPE-1). J Biol Chem 2005 1.03
23 Tendon development requires regulation of cell condensation and cell shape via cadherin-11-mediated cell-cell junctions. Mol Cell Biol 2007 1.01
24 Active negative control of collagen fibrillogenesis in vivo. Intracellular cleavage of the type I procollagen propeptides in tendon fibroblasts without intracellular fibrils. J Biol Chem 2008 1.01
25 Tendon is covered by a basement membrane epithelium that is required for cell retention and the prevention of adhesion formation. PLoS One 2011 1.01
26 A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia. Hum Mol Genet 2010 1.00
27 An experimental model for studying the biomechanics of embryonic tendon: Evidence that the development of mechanical properties depends on the actinomyosin machinery. Matrix Biol 2010 0.97
28 Nonmuscle myosin II powered transport of newly formed collagen fibrils at the plasma membrane. Proc Natl Acad Sci U S A 2013 0.95
29 Deletion of epidermal growth factor-like domains converts mammalian tolloid into a chordinase and effective procollagen C-proteinase. J Biol Chem 2004 0.94
30 Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke. Hum Mol Genet 2013 0.93
31 Electron microscopy of collagen fibril structure in vitro and in vivo including three-dimensional reconstruction. Methods Cell Biol 2008 0.92
32 Three-dimensional aspects of matrix assembly by cells in the developing cornea. Proc Natl Acad Sci U S A 2014 0.92
33 Synthesis of embryonic tendon-like tissue by human marrow stromal/mesenchymal stem cells requires a three-dimensional environment and transforming growth factor β3. Matrix Biol 2010 0.92
34 Collagen XXVII organises the pericellular matrix in the growth plate. PLoS One 2011 0.90
35 Slow stretching that mimics embryonic growth rate stimulates structural and mechanical development of tendon-like tissue in vitro. Dev Dyn 2011 0.90
36 3-D ultrastructure and collagen composition of healthy and overloaded human tendon: evidence of tenocyte and matrix buckling. J Anat 2014 0.88
37 Analysis of collagen fibril diameter distribution in connective tissues using small-angle X-ray scattering. Biochim Biophys Acta 2004 0.87
38 Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase. FEBS Lett 2009 0.86
39 The precision of lateral size control in the assembly of corneal collagen fibrils. J Mol Biol 2005 0.85
40 Post-translational modification of bone morphogenetic protein-1 is required for secretion and stability of the protein. J Biol Chem 2002 0.85
41 Electron microscopy in cell-matrix research. Methods 2008 0.84
42 Growth of collagen fibril seeds from embryonic tendon: fractured fibril ends nucleate new tip growth. J Mol Biol 2010 0.81
43 Tendon functional extracellular matrix. J Orthop Res 2015 0.81
44 A complete domain structure of Drosophila tolloid is required for cleavage of short gastrulation. J Biol Chem 2006 0.80
45 Stepwise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ. Biochem J 2012 0.80
46 Modification of the composition of articular cartilage collagen fibrils with increasing age. Connect Tissue Res 2008 0.80
47 First evidence of bone morphogenetic protein 1 expression and activity in sheep ovarian follicles. Biol Reprod 2010 0.78
48 Fibrin gels exhibit improved biological, structural, and mechanical properties compared with collagen gels in cell-based tendon tissue-engineered constructs. Tissue Eng Part A 2014 0.78
49 Serial block face-scanning electron microscopy: a tool for studying embryonic development at the cell-matrix interface. Birth Defects Res C Embryo Today 2015 0.76