Voluntary Aerobic Exercise Reverses Frailty in Old Mice.

PubWeight™: 0.82‹?›

🔗 View Article (PMID 25271307)

Published in J Gerontol A Biol Sci Med Sci on September 30, 2014

Authors

Ted G Graber1, Lisa Ferguson-Stegall1, Haiming Liu1, LaDora V Thompson2

Author Affiliations

1: Department of Physical Medicine and Rehabilitation, University of Minnesota Medical School, Minneapolis.
2: Department of Physical Medicine and Rehabilitation, University of Minnesota Medical School, Minneapolis. thomp067@umn.edu.

Articles cited by this

Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci (2001) 42.21

FUNCTIONAL EVALUATION: THE BARTHEL INDEX. Md State Med J (1965) 38.57

Phenotype of frailty: characterization in the women's health and aging studies. J Gerontol A Biol Sci Med Sci (2006) 8.00

Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc (2006) 6.81

High-intensity strength training in nonagenarians. Effects on skeletal muscle. JAMA (1990) 5.45

A brief clinical instrument to classify frailty in elderly people. Lancet (1999) 3.27

Tests to assess motor phenotype in mice: a user's guide. Nat Rev Neurosci (2009) 2.60

Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse. J Appl Physiol (1985) (2001) 2.24

Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise. Proc Natl Acad Sci U S A (2010) 2.22

Skeletal muscle adaptations to endurance training in 60- to 70-yr-old men and women. J Appl Physiol (1985) (1992) 2.06

PGC1α and mitochondrial metabolism--emerging concepts and relevance in ageing and neurodegenerative disorders. J Cell Sci (2012) 1.73

PGC-1alpha plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle. Am J Physiol Cell Physiol (2009) 1.72

A clinical frailty index in aging mice: comparisons with frailty index data in humans. J Gerontol A Biol Sci Med Sci (2013) 1.69

Ca2+ and AMPK both mediate stimulation of glucose transport by muscle contractions. Diabetes (2004) 1.60

The functional effects of physical exercise training in frail older people : a systematic review. Sports Med (2008) 1.46

Compatibility of high-intensity strength and endurance training on hormonal and skeletal muscle adaptations. J Appl Physiol (1985) (1995) 1.46

A procedure for creating a frailty index based on deficit accumulation in aging mice. J Gerontol A Biol Sci Med Sci (2011) 1.41

Exercise as an intervention for frailty. Clin Geriatr Med (2011) 1.40

The physical and biological characterization of a frail mouse model. J Gerontol A Biol Sci Med Sci (2008) 1.39

C57BL/6 neuromuscular healthspan scoring system. J Gerontol A Biol Sci Med Sci (2013) 1.38

Changes in myosin heavy chain mRNA and protein expression in human skeletal muscle with age and endurance exercise training. J Appl Physiol (1985) (2005) 1.36

Improved physical performance in older adults undertaking a short-term programme of high-velocity resistance training. Gerontology (2005) 1.30

Effect of exercise on longevity, body weight, locomotor performance, and passive-avoidance memory of C57BL/6J mice. Neurobiol Aging (1985) 1.30

Effect of resistance training on skeletal muscle-specific force in elderly humans. J Appl Physiol (1985) (2003) 1.25

Aerobic exercise reverses arterial inflammation with aging in mice. Am J Physiol Heart Circ Physiol (2011) 1.18

Clinically relevant frailty index for mice. J Gerontol A Biol Sci Med Sci (2013) 1.10

Effect of voluntary wheel-running exercise on muscles of the mdx mouse. Neuromuscul Disord (1995) 1.09

Targeting strategies: an overview of criteria and outcomes. J Am Geriatr Soc (1991) 1.00

Measuring participation after stroke: a review of frequently used tools. Arch Phys Med Rehabil (2012) 0.95

Exercise dosing to retain resistance training adaptations in young and older adults. Med Sci Sports Exerc (2011) 0.91

The resist diabetes trial: Rationale, design, and methods of a hybrid efficacy/effectiveness intervention trial for resistance training maintenance to improve glucose homeostasis in older prediabetic adults. Contemp Clin Trials (2013) 0.91

Myosin heavy chain plasticity in aging skeletal muscle with aerobic exercise training. J Gerontol A Biol Sci Med Sci (2011) 0.90

The roles of myosin ATPase activity and myosin light chain relative content in the slowing of type IIB fibers with hindlimb unweighting in rats. Am J Physiol Cell Physiol (2007) 0.84

Functional status in the young-old: establishing a working prototype of an extended-instrumental activities of daily living scale. J Gerontol A Biol Sci Med Sci (2013) 0.83

IIx and slow myosin expression follow mitochondrial increases in transforming muscle fibers. Am J Physiol (1993) 0.81

Resistance Training Is an Effective Tool against Metabolic and Frailty Syndromes. Adv Prev Med (2010) 0.80

Concurrent and construct validity of scores on the Timed Movement Battery. Phys Ther (2001) 0.80

Sarcopenia and decreased muscle strength in the elderly woman: resistance training as a safe and effective intervention. J Women Aging (1999) 0.77