Published in Cell Transplant on October 06, 2014
Tolvaptan in patients with autosomal dominant polycystic kidney disease. N Engl J Med (2012) 9.88
Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res (2004) 6.34
Autosomal dominant polycystic kidney disease: the last 3 years. Kidney Int (2009) 3.66
Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. J Am Soc Nephrol (2004) 3.41
Validation of volume-pressure recording tail-cuff blood pressure measurements. Am J Hypertens (2008) 2.45
Endothelial progenitor cells restore renal function in chronic experimental renovascular disease. Circulation (2009) 2.24
Polycystin 1 is required for the structural integrity of blood vessels. Proc Natl Acad Sci U S A (2000) 2.23
Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium. Stem Cell Res (2008) 1.97
Understanding the coronary circulation through studies at the microvascular level. Circulation (1990) 1.76
Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging. Stem Cells (2009) 1.58
The pck rat: a new model that resembles human autosomal dominant polycystic kidney and liver disease. Kidney Int (2001) 1.56
Polycystic kidney disease: genes, proteins, animal models, disease mechanisms and therapeutic opportunities. J Intern Med (2007) 1.54
Molecular imaging of bone marrow mononuclear cell survival and homing in murine peripheral artery disease. JACC Cardiovasc Imaging (2012) 1.49
Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney disease. Am J Pathol (2004) 1.49
Noninvasive monitoring of oxidative stress in transplanted mesenchymal stromal cells. JACC Cardiovasc Imaging (2013) 1.45
Adipose tissue-derived mesenchymal stem cells improve revascularization outcomes to restore renal function in swine atherosclerotic renal artery stenosis. Stem Cells (2012) 1.44
Angiotensin II-NAD(P)H oxidase-stimulated superoxide modifies tubulovascular nitric oxide cross-talk in renal outer medulla. Hypertension (2003) 1.38
Stem cell options for kidney disease. J Pathol (2009) 1.38
Cardiovascular abnormalities in autosomal-dominant polycystic kidney disease. Nat Rev Nephrol (2009) 1.36
Endothelial dysfunction and reduced nitric oxide in resistance arteries in autosomal-dominant polycystic kidney disease. Kidney Int (2003) 1.29
Bone marrow mesenchymal stem cells ameliorate rat acute renal failure by differentiation into renal tubular epithelial-like cells. Int J Mol Med (2008) 1.28
Long term non-invasive imaging of embryonic stem cells using reporter genes. Nat Protoc (2009) 1.27
Analysis of the polycystins in aortic vascular smooth muscle cells. J Am Soc Nephrol (2003) 1.27
Increased renal medullary oxidative stress produces hypertension. Hypertension (2002) 1.24
Report of the National Heart, Lung, and Blood Institute working group on the translation of cardiovascular molecular imaging. Circulation (2011) 1.23
Increased left ventricular mass in children with autosomal dominant polycystic kidney disease and borderline hypertension. Kidney Int (2008) 1.21
The potential of bone marrow-derived cells to differentiate to glomerular mesangial cells. J Am Soc Nephrol (2001) 1.20
Mesenchymal stem cells and endothelial progenitor cells decrease renal injury in experimental swine renal artery stenosis through different mechanisms. Stem Cells (2013) 1.16
Bone marrow cells contribute to regeneration of damaged glomerular endothelial cells. Kidney Int (2005) 1.16
Improved survival of mesenchymal stromal cell after hypoxia preconditioning: role of oxidative stress. Life Sci (2010) 1.14
Mesenchymal stem cells improve medullary inflammation and fibrosis after revascularization of swine atherosclerotic renal artery stenosis. PLoS One (2013) 1.12
Intrarenal injection of bone marrow-derived angiogenic cells reduces endothelial injury and mesangial cell activation in experimental glomerulonephritis. J Am Soc Nephrol (2005) 1.11
Image-guided cardiac cell delivery using high-resolution small-animal ultrasound. Mol Ther (2005) 1.11
Asymmetric dimethylarginine and lipid peroxidation products in early autosomal dominant polycystic kidney disease. Am J Kidney Dis (2008) 1.08
Timing of bone marrow cell delivery has minimal effects on cell viability and cardiac recovery after myocardial infarction. Circ Cardiovasc Imaging (2009) 1.08
Altered myocardial microvascular 3D architecture in experimental hypercholesterolemia. Circulation (2000) 1.07
Characteristics of hypertension in young adults with autosomal dominant polycystic kidney disease compared with the general U.S. population. Am J Hypertens (2004) 1.07
Preconditioning promotes survival and angiomyogenic potential of mesenchymal stem cells in the infarcted heart via NF-kappaB signaling. Antioxid Redox Signal (2010) 1.07
Genetic deficiency of Smad3 protects the kidneys from atrophy and interstitial fibrosis in 2K1C hypertension. Am J Physiol Renal Physiol (2012) 1.05
Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1. Hum Mol Genet (2009) 1.03
Antioxidants improve early survival of cardiomyoblasts after transplantation to the myocardium. Mol Imaging Biol (2009) 1.02
Microcomputed tomography of kidneys following chronic bile duct ligation. Kidney Int (2000) 0.95
Polycystic kidney disease in 2011: Connecting the dots toward a polycystic kidney disease therapy. Nat Rev Nephrol (2011) 0.93
Effect of calcium-sensing receptor activation in models of autosomal recessive or dominant polycystic kidney disease. Nephrol Dial Transplant (2008) 0.92
ETA receptor blockade induces tubular cell proliferation and cyst growth in rats with polycystic kidney disease. J Am Soc Nephrol (2003) 0.87
Paracrine factors from human placental multipotent mesenchymal stromal cells protect endothelium from oxidative injury via STAT3 and manganese superoxide dismutase activation. Biol Reprod (2010) 0.86
Intra-renal arterial injection of autologous bone marrow mesenchymal stromal cells ameliorates cisplatin-induced acute kidney injury in a rhesus Macaque mulatta monkey model. Cytotherapy (2014) 0.86
The genetics of vascular complications in autosomal dominant polycystic kidney disease (ADPKD). Curr Hypertens Rev (2013) 0.84
C-kit(+) cells isolated from developing kidneys are a novel population of stem cells with regenerative potential. Stem Cells (2013) 0.82
Polycystic kidneys have decreased vascular density: a micro-CT study. Microcirculation (2013) 0.81
In-center hemodialysis six times per week versus three times per week. N Engl J Med (2010) 10.73
Autosomal dominant polycystic kidney disease. Lancet (2007) 8.55
Volume progression in polycystic kidney disease. N Engl J Med (2006) 7.16
Endothelial dysfunction: a marker of atherosclerotic risk. Arterioscler Thromb Vasc Biol (2003) 6.04
Progress and prospects in rat genetics: a community view. Nat Genet (2008) 6.01
Blood pressure in early autosomal dominant polycystic kidney disease. N Engl J Med (2014) 5.01
The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat Genet (2002) 4.54
Inhibition of renal cystic disease development and progression by a vasopressin V2 receptor antagonist. Nat Med (2003) 3.78
Autosomal dominant polycystic kidney disease: the last 3 years. Kidney Int (2009) 3.66
Randomized clinical trial of long-acting somatostatin for autosomal dominant polycystic kidney and liver disease. J Am Soc Nephrol (2010) 3.47
Comprehensive molecular diagnostics in autosomal dominant polycystic kidney disease. J Am Soc Nephrol (2007) 3.26
Assessment of endothelial function by non-invasive peripheral arterial tonometry predicts late cardiovascular adverse events. Eur Heart J (2010) 3.22
The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat. Nat Genet (2006) 3.19
US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. Radiology (2008) 3.15
Effective treatment of an orthologous model of autosomal dominant polycystic kidney disease. Nat Med (2004) 3.09
Incompletely penetrant PKD1 alleles suggest a role for gene dosage in cyst initiation in polycystic kidney disease. Kidney Int (2009) 2.99
Mechanisms of Disease: autosomal dominant and recessive polycystic kidney diseases. Nat Clin Pract Nephrol (2006) 2.95
Effectiveness of vasopressin V2 receptor antagonists OPC-31260 and OPC-41061 on polycystic kidney disease development in the PCK rat. J Am Soc Nephrol (2005) 2.92
Kidney volume and functional outcomes in autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol (2012) 2.78
Vasopressin directly regulates cyst growth in polycystic kidney disease. J Am Soc Nephrol (2007) 2.71
Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3',5'-cyclic monophosphate. Gastroenterology (2006) 2.68
High leukocyte count is associated with peripheral vascular dysfunction in individuals with low cardiovascular risk. Circ J (2012) 2.61
The interaction between coronary endothelial dysfunction, local oxidative stress, and endogenous nitric oxide in humans. Hypertension (2008) 2.56
Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia. Hum Mol Genet (2003) 2.55
Chronic proteasome inhibition contributes to coronary atherosclerosis. Circ Res (2007) 2.55
Trends in cause of death after percutaneous coronary intervention. Circulation (2014) 2.52
Clinical and molecular characterization defines a broadened spectrum of autosomal recessive polycystic kidney disease (ARPKD). Medicine (Baltimore) (2006) 2.34
Endothelial progenitor cells restore renal function in chronic experimental renovascular disease. Circulation (2009) 2.24
Comparison of mathematic models for assessment of glomerular filtration rate with electron-beam CT in pigs. Radiology (2007) 2.17
Preserved oxygenation despite reduced blood flow in poststenotic kidneys in human atherosclerotic renal artery stenosis. Hypertension (2010) 2.17
Assessment of renal hemodynamics and function in pigs with 64-section multidetector CT: comparison with electron-beam CT. Radiology (2007) 2.14
Characterization of PKD protein-positive exosome-like vesicles. J Am Soc Nephrol (2009) 2.13
Molecular pathogenesis of ADPKD: the polycystin complex gets complex. Kidney Int (2005) 2.13
The long-term effect of coronary stenting on epicardial and microvascular endothelial function. Circ Cardiovasc Interv (2012) 2.03
Distinct renal injury in early atherosclerosis and renovascular disease. Circulation (2002) 2.01
Lipoprotein-associated phospholipase A2 is an independent marker for coronary endothelial dysfunction in humans. Arterioscler Thromb Vasc Biol (2005) 2.00
Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. J Am Soc Nephrol (2006) 1.95
Mechanisms of renal structural alterations in combined hypercholesterolemia and renal artery stenosis. Arterioscler Thromb Vasc Biol (2003) 1.91
Local production of lipoprotein-associated phospholipase A2 and lysophosphatidylcholine in the coronary circulation: association with early coronary atherosclerosis and endothelial dysfunction in humans. Circulation (2007) 1.89
The chemokine monocyte chemoattractant protein-1 contributes to renal dysfunction in swine renovascular hypertension. J Hypertens (2009) 1.88
Cortical microvascular remodeling in the stenotic kidney: role of increased oxidative stress. Arterioscler Thromb Vasc Biol (2004) 1.87
Ubiquitin and ubiquitin-like proteins in protein regulation. Circ Res (2007) 1.87
Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat. Gastroenterology (2003) 1.80
Simvastatin abates development of renal fibrosis in experimental renovascular disease. J Hypertens (2008) 1.78
Expression of lipoprotein-associated phospholipase A(2) in carotid artery plaques predicts long-term cardiac outcome. Eur Heart J (2009) 1.77
Long-term outcomes of fractional flow reserve-guided vs. angiography-guided percutaneous coronary intervention in contemporary practice. Eur Heart J (2013) 1.76
Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity. J Clin Invest (2012) 1.74
Potential role of the ubiquitin-proteasome system in atherosclerosis: aspects of a protein quality disease. J Am Coll Cardiol (2008) 1.74
Human ADPKD primary cyst epithelial cells with a novel, single codon deletion in the PKD1 gene exhibit defective ciliary polycystin localization and loss of flow-induced Ca2+ signaling. Am J Physiol Renal Physiol (2006) 1.72
Follow-up of intracranial aneurysms in autosomal-dominant polycystic kidney disease. Kidney Int (2004) 1.71
Antioxidant intervention blunts renal injury in experimental renovascular disease. J Am Soc Nephrol (2004) 1.70
Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia. FASEB J (2006) 1.69
Efficacy and safety of atrasentan in patients with cardiovascular risk and early atherosclerosis. Hypertension (2008) 1.67
A complete mutation screen of the ADPKD genes by DHPLC. Kidney Int (2002) 1.66
Human renovascular disease: estimating fractional tissue hypoxia to analyze blood oxygen level-dependent MR. Radiology (2013) 1.65
Angiotensin blockade in late autosomal dominant polycystic kidney disease. N Engl J Med (2014) 1.64
Molecular diagnostics of Meckel-Gruber syndrome highlights phenotypic differences between MKS1 and MKS3. Hum Genet (2007) 1.64
Prognostic value of circulating pregnancy-associated plasma protein levels in patients with chronic stable angina. Eur Heart J (2006) 1.63
Quantitative assessment of hepatic fibrosis in an animal model with magnetic resonance elastography. Magn Reson Med (2007) 1.61
Ciliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3. Hum Mol Genet (2009) 1.61
The position of the polycystic kidney disease 1 (PKD1) gene mutation correlates with the severity of renal disease. J Am Soc Nephrol (2002) 1.60
Genotype-phenotype correlations in autosomal dominant and autosomal recessive polycystic kidney disease. J Am Soc Nephrol (2007) 1.60
Simvastatin preserves diastolic function in experimental hypercholesterolemia independently of its lipid lowering effect. Atherosclerosis (2011) 1.59
Role of circulating osteogenic progenitor cells in calcific aortic stenosis. J Am Coll Cardiol (2012) 1.59
Coronary endothelial dysfunction in patients with early coronary artery disease is associated with the increase in intravascular lipid core plaque. Eur Heart J (2013) 1.59
Characterization of large rearrangements in autosomal dominant polycystic kidney disease and the PKD1/TSC2 contiguous gene syndrome. Kidney Int (2008) 1.58
Coronary microcirculatory vasodilator function in relation to risk factors among patients without obstructive coronary disease and low to intermediate Framingham score. Eur Heart J (2009) 1.58
Simvastatin preserves the structure of coronary adventitial vasa vasorum in experimental hypercholesterolemia independent of lipid lowering. Circulation (2002) 1.57
Identification of gene mutations in autosomal dominant polycystic kidney disease through targeted resequencing. J Am Soc Nephrol (2012) 1.57
Early experimental obesity is associated with coronary endothelial dysfunction and oxidative stress. Am J Physiol Heart Circ Physiol (2006) 1.56
Renal vein cytokine release as an index of renal parenchymal inflammation in chronic experimental renal artery stenosis. Nephrol Dial Transplant (2013) 1.56
Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex. J Biol Chem (2002) 1.56
Incompletely penetrant PKD1 alleles mimic the renal manifestations of ARPKD. J Am Soc Nephrol (2010) 1.52
Enhanced expression of Lp-PLA2 and lysophosphatidylcholine in symptomatic carotid atherosclerotic plaques. Stroke (2008) 1.52
The use of magnetic resonance to evaluate tissue oxygenation in renal artery stenosis. J Am Soc Nephrol (2008) 1.51
Normal vascular function as a prerequisite for the absence of coronary calcification in patients free of cardiovascular disease and diabetes. Circ J (2012) 1.51
The ENOS polymorphism is not associated with severity of renal disease in polycystic kidney disease 1. Am J Kidney Dis (2003) 1.51
Blood oxygen level-dependent measurement of acute intra-renal ischemia. Kidney Int (2004) 1.50
Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney disease. Am J Pathol (2004) 1.49
Association of mutation position in polycystic kidney disease 1 (PKD1) gene and development of a vascular phenotype. Lancet (2003) 1.47
The ubiquitin-proteasome system in cardiovascular diseases-a hypothesis extended. Cardiovasc Res (2004) 1.46
Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia. Circulation (2004) 1.46
B9D1 is revealed as a novel Meckel syndrome (MKS) gene by targeted exon-enriched next-generation sequencing and deletion analysis. Hum Mol Genet (2011) 1.45
Noninvasive monitoring of oxidative stress in transplanted mesenchymal stromal cells. JACC Cardiovasc Imaging (2013) 1.45
Reversal of experimental renovascular hypertension restores coronary microvascular function and architecture. Am J Hypertens (2011) 1.45
Adipose tissue-derived mesenchymal stem cells improve revascularization outcomes to restore renal function in swine atherosclerotic renal artery stenosis. Stem Cells (2012) 1.44
Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. Hum Mol Genet (2002) 1.43
PKHD1 mutations in autosomal recessive polycystic kidney disease (ARPKD). Hum Mutat (2004) 1.40
Comprehensive mutation screening in 55 probands with type 1 primary hyperoxaluria shows feasibility of a gene-based diagnosis. J Am Soc Nephrol (2007) 1.39
Kidney in early atherosclerosis. Hypertension (2005) 1.39
A polycystin-1 multiprotein complex is disrupted in polycystic kidney disease cells. Mol Biol Cell (2004) 1.39
Pkd2 haploinsufficiency alters intracellular calcium regulation in vascular smooth muscle cells. Hum Mol Genet (2003) 1.39
Simvastatin prevents coronary microvascular remodeling in renovascular hypertensive pigs. J Am Soc Nephrol (2007) 1.38