Published in Cancer Lett on October 07, 2014
Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance. Nat Commun (2016) 0.87
PGRMC1 participates in late events of bovine granulosa cells mitosis and oocyte meiosis. Cell Cycle (2016) 0.84
Progesterone receptor membrane component 1 promotes survival of human breast cancer cells and the growth of xenograft tumors. Cancer Biol Ther (2016) 0.80
Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors. Nat Rev Mol Cell Biol (2016) 0.78
Conditional Ablation of Progesterone Receptor Membrane Component 1 Results in Subfertility in the Female and Development of Endometrial Cysts. Endocrinology (2016) 0.76
PGRMC1 Elevation in Multiple Cancers and Essential Role in Stem Cell Survival. Adv Lung Cancer (Irvine) (2016) 0.75
Membrane Associated Progesterone Receptors: Promiscuous Proteins with Pleiotropic Functions - Focus on Interactions with Cytochromes P450. Front Pharmacol (2017) 0.75
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen. Cell (2006) 18.81
Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial. JAMA (2003) 10.61
Endometrial carcinoma. N Engl J Med (1996) 3.31
Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes. Cell Metab (2007) 2.30
Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by 18F-FDG-microPET or external caliper. BMC Med Imaging (2008) 2.30
Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells. Nat Methods (2005) 2.24
Progesterone receptor membrane component 1: an integrative review. J Steroid Biochem Mol Biol (2007) 2.06
Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site. Nat Commun (2011) 1.86
Progesterone membrane receptor component 1 expression in the immature rat ovary and its role in mediating progesterone's antiapoptotic action. Endocrinology (2006) 1.75
Purification and partial sequencing of high-affinity progesterone-binding site(s) from porcine liver membranes. Eur J Biochem (1996) 1.70
The postimplantation embryo differentially regulates endometrial gene expression and decidualization. Endocrinology (2007) 1.62
PGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling, P450 activation and drug binding. Pharmacol Ther (2008) 1.41
Progestin alone as primary treatment of endometrial carcinoma in premenopausal women. Report of seven cases and review of the literature. Cancer (1997) 1.23
Progesterone receptor membrane component 1 (Pgrmc1): a heme-1 domain protein that promotes tumorigenesis and is inhibited by a small molecule. J Pharmacol Exp Ther (2010) 1.21
Progesterone regulation of human granulosa/luteal cell viability by an RU486-independent mechanism. J Clin Endocrinol Metab (2006) 1.20
Progesterone receptor membrane component 1--many tasks for a versatile protein. Steroids (2007) 1.19
Microarray profiling of progesterone-regulated endometrial genes during the rhesus monkey secretory phase. Reprod Biol Endocrinol (2004) 1.18
Progesterone increases rat neural progenitor cell cycle gene expression and proliferation via extracellularly regulated kinase and progesterone receptor membrane components 1 and 2. Endocrinology (2009) 1.15
Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1. J Clin Endocrinol Metab (2008) 1.14
Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. Eukaryot Cell (2003) 1.07
Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1. Breast Cancer Res (2008) 1.07
Expression of progesterone receptor membrane component 1 and its partner serpine 1 mRNA binding protein in uterine and placental tissues of the mouse and human. Mol Cell Endocrinol (2008) 1.07
A novel role for progesterone and progesterone receptor membrane component 1 in regulating spindle microtubule stability during rat and human ovarian cell mitosis. Biol Reprod (2010) 1.04
Overexpression of the cytochrome p450 activator hpr6 (heme-1 domain protein/human progesterone receptor) in tumors. Tumour Biol (2005) 1.04
Progesterone receptor membrane component-1 regulates the development and Cisplatin sensitivity of human ovarian tumors in athymic nude mice. Endocrinology (2009) 1.02
Proteomic characterization of midproliferative and midsecretory human endometrium. J Proteome Res (2009) 1.01
Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver. Carcinogenesis (1996) 1.01
Endometrial miR-181a and miR-98 expression is altered during transition from normal into cancerous state and target PGR, PGRMC1, CYP19A1, DDX3X, and TIMP3. J Clin Endocrinol Metab (2012) 1.00
Progesterone signaling mediated through progesterone receptor membrane component-1 in ovarian cells with special emphasis on ovarian cancer. Steroids (2011) 1.00
Localization and topology of ratp28, a member of a novel family of putative steroid-binding proteins. Biochim Biophys Acta (2000) 0.99
Endometrial cancer: hormonal factors, the perimenopausal "window of risk," and isoflavones. J Clin Endocrinol Metab (2002) 0.98
Elevated progesterone receptor membrane component 1/sigma-2 receptor levels in lung tumors and plasma from lung cancer patients. Int J Cancer (2011) 0.96
Evidence for a genomic mechanism of action for progesterone receptor membrane component-1. Steroids (2012) 0.95
Reversal of paclitaxel resistance in epithelial ovarian carcinoma cells by a MUC1 aptamer-let-7i chimera. Cancer Invest (2012) 0.94
Progesterone regulation of progesterone receptor membrane component 1 (PGRMC1) sumoylation and transcriptional activity in spontaneously immortalized granulosa cells. Endocrinology (2012) 0.94
Fertility sparing treatment of complex atypical hyperplasia and low grade endometrial cancer using oral progestin. Gynecol Oncol (2014) 0.94
Enhancement of cell surface expression and receptor functions of membrane progestin receptor α (mPRα) by progesterone receptor membrane component 1 (PGRMC1): evidence for a role of PGRMC1 as an adaptor protein for steroid receptors. Endocrinology (2014) 0.93
Involvement of let-7/miR-98 microRNAs in the regulation of progesterone receptor membrane component 1 expression in ovarian cancer cells. Oncol Rep (2011) 0.91
Non-canonical progesterone signaling in granulosa cell function. Reproduction (2014) 0.91
Progesterone receptor membrane component 1 and its role in ovarian follicle growth. Front Neurosci (2013) 0.91
Caenorhabditis elegans VEM-1, a novel membrane protein, regulates the guidance of ventral nerve cord-associated axons. J Neurosci (2004) 0.89
Signaling mechanisms in tumor necrosis factor alpha-induced death of microvascular endothelial cells of the corpus luteum. Reprod Biol Endocrinol (2003) 0.89
Old and new perspectives in the pharmacological treatment of advanced or recurrent endometrial cancer: Hormonal therapy, chemotherapy and molecularly targeted therapies. Crit Rev Oncol Hematol (2006) 0.88
Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle. Eur J Histochem (2011) 0.86
Progesterone receptor A and B expression and progestagen treatment in growth and spread of endometrial cancer cells in nude mice. Endocr Relat Cancer (2004) 0.86
Transcriptional analysis of novel hormone receptors PGRMC1 and PGRMC2 as potential biomarkers of breast adenocarcinoma staging. J Surg Res (2010) 0.85
Alterations in progesterone receptor membrane component 2 (PGRMC2) in the endometrium of macaques afflicted with advanced endometriosis. Mol Hum Reprod (2012) 0.84
Possible role of PGRMC1 in breast cancer development. Climacteric (2013) 0.83
Effect of progesterone on Th1/Th2/Th17 and regulatory T cell-related genes in peripheral blood mononuclear cells during pregnancy in cows. Vet Res Commun (2012) 0.82
Progestogens and membrane-initiated effects on the proliferation of human breast cancer cells. Climacteric (2012) 0.82
Oocytes isolated from dairy cows with reduced ovarian reserve have a high frequency of aneuploidy and alterations in the localization of progesterone receptor membrane component 1 and aurora kinase B. Biol Reprod (2013) 0.81
Advanced and recurrent endometrial carcinoma: hormonal therapy. Semin Oncol (1994) 0.81
Advantages of COS-1 monkey kidney epithelial cells as packaging host for small-volume production of high-quality recombinant lentiviruses. J Virol Methods (2009) 0.81
PGRMC1 and PGRMC2 in uterine physiology and disease. Front Neurosci (2013) 0.80
Progesterone receptors in endometrial cancer invasion and metastasis: development of a mouse model. Steroids (2003) 0.78