Correlation of apical fluid-regulating channel proteins with lung function in human COPD lungs.

Therapeutic Approaches to Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Chronic Bronchitis. Ann Am Thorac Soc (2016) 0.87

Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases. Sci Rep (2016) 0.75

Elastase-Induced Parenchymal Disruption and Airway Hyper Responsiveness in Mouse Precision Cut Lung Slices: Toward an Ex vivo COPD Model. Front Physiol (2017) 0.75

Epithelial Sodium and Chloride Channels and Asthma. Chin Med J (Engl) (2015) 0.75

Global burden of COPD: systematic review and meta-analysis. Eur Respir J (2006) 7.00

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice. Nat Med (2004) 5.24

A quantification of the lung surface area in emphysema using computed tomography. Am J Respir Crit Care Med (1999) 2.68

Functional ion channels in pulmonary alveolar type I cells support a role for type I cells in lung ion transport. Proc Natl Acad Sci U S A (2006) 2.06

Meta-analyses on suspected chronic obstructive pulmonary disease genes: a summary of 20 years' research. Am J Respir Crit Care Med (2009) 2.04

Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B. Biochem J (2002) 2.02

Alveolar epithelial type I cells contain transport proteins and transport sodium, supporting an active role for type I cells in regulation of lung liquid homeostasis. Proc Natl Acad Sci U S A (2002) 1.95

Genetic risk factors for chronic obstructive pulmonary disease. Eur Respir J (1997) 1.79

Airway surface liquid volume regulates ENaC by altering the serine protease-protease inhibitor balance: a mechanism for sodium hyperabsorption in cystic fibrosis. J Biol Chem (2006) 1.77

The contribution of epithelial sodium channels to alveolar function in health and disease. Annu Rev Physiol (2009) 1.72

Exhaled breath condensate biomarkers in COPD. Eur Respir J (2008) 1.71

Regulation of airway surface liquid volume by human airway epithelia. Pflugers Arch (2002) 1.66

Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice. Am J Respir Crit Care Med (2008) 1.64

Development of chronic bronchitis and emphysema in beta-epithelial Na+ channel-overexpressing mice. Am J Respir Crit Care Med (2007) 1.60

Global lung health: the colliding epidemics of tuberculosis, tobacco smoking, HIV and COPD. Eur Respir J (2010) 1.57

Characteristics of Cl- uptake in rat alveolar type I cells. Am J Physiol Lung Cell Mol Physiol (2009) 1.56

Aquaporin-5 dependent fluid secretion in airway submucosal glands. J Biol Chem (2001) 1.53

Correlation of lung surface area to apoptosis and proliferation in human emphysema. Eur Respir J (2005) 1.51

The mysterious pulmonary brush cell: a cell in search of a function. Am J Respir Crit Care Med (2005) 1.50

Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C{delta}-mediated mechanism. Am J Pathol (2005) 1.50

Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM. Proc Natl Acad Sci U S A (2010) 1.44

An overview of the pathogenesis of cystic fibrosis lung disease. Adv Drug Deliv Rev (2002) 1.41

Noncoordinate regulation of epithelial Na channel and Na pump subunit mRNAs in kidney and colon by aldosterone. Am J Physiol (1997) 1.40

The cytosolic termini of the beta- and gamma-ENaC subunits are involved in the functional interactions between cystic fibrosis transmembrane conductance regulator and epithelial sodium channel. J Biol Chem (2000) 1.23

Mucus secretion by single tracheal submucosal glands from normal and cystic fibrosis transmembrane conductance regulator knockout mice. J Physiol (2007) 1.21

Assessment of the CFTR and ENaC association. Mol Biosyst (2008) 1.19

Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment. J Immunol (2009) 1.17

Role of aquaporin water channels in airway fluid transport, humidification, and surface liquid hydration. J Gen Physiol (2001) 1.16

Critical modifier role of membrane-cystic fibrosis transmembrane conductance regulator-dependent ceramide signaling in lung injury and emphysema. J Immunol (2010) 1.14

Epithelial sodium channels regulate cystic fibrosis transmembrane conductance regulator chloride channels in Xenopus oocytes. J Biol Chem (2000) 1.09

Superoxide dismutase 3 polymorphism associated with reduced lung function in two large populations. Am J Respir Crit Care Med (2008) 1.09

Critical role of CFTR-dependent lipid rafts in cigarette smoke-induced lung epithelial injury. Am J Physiol Lung Cell Mol Physiol (2011) 1.09

Asthma and chronic obstructive pulmonary disease: common genes, common environments? Am J Respir Crit Care Med (2011) 1.06

Invited review: Active fluid clearance from the distal air spaces of the lung. J Appl Physiol (1985) (2002) 1.06

In vivo monitoring of cystic fibrosis-like lung disease in mice by volumetric computed tomography. Eur Respir J (2011) 1.05

Modulation of alveolar fluid clearance by reactive oxygen-nitrogen intermediates. Am J Physiol Lung Cell Mol Physiol (2007) 1.00

Decreased expression of human aquaporin-5 correlated with mucus overproduction in airways of chronic obstructive pulmonary disease. Acta Pharmacol Sin (2007) 0.98

Cigarette smoke and CFTR: implications in the pathogenesis of COPD. Am J Physiol Lung Cell Mol Physiol (2013) 0.96

Cystic fibrosis transmembrane conductance regulator differentially regulates human and mouse epithelial sodium channels in Xenopus oocytes. J Biol Chem (2004) 0.94

Epithelial sodium channels in the adult lung--important modulators of pulmonary health and disease. Adv Exp Med Biol (2007) 0.93

Superoxide dismutases, lung function and bronchial responsiveness in a general population. Eur Respir J (2009) 0.93

Importance of ENaC-mediated sodium transport in alveolar fluid clearance using genetically-engineered mice. Cell Physiol Biochem (2009) 0.91

Expression and regulation of normal and polymorphic epithelial sodium channel by human lymphocytes. J Biol Chem (2000) 0.87

Expression of cystic fibrosis transmembrane conductance regulator in the human distal lung. Hum Pathol (2007) 0.85

Animal models of pulmonary emphysema. Curr Drug Targets Inflamm Allergy (2005) 0.85

Malondialdehyde and superoxide dismutase correlate with FEV(1) in patients with COPD associated with wood smoke exposure and tobacco smoking. Inhal Toxicol (2010) 0.84

Delta F508 mutation of cystic fibrosis gene is not found in chronic bronchitis with severe obstruction in Japan. Am Rev Respir Dis (1992) 0.83

Amiloride-sensitive sodium conductance in human B lymphoid cells. Am J Physiol (1993) 0.83

Genetic variation of αENaC influences lung diffusion during exercise in humans. Respir Physiol Neurobiol (2011) 0.82

Impaired stimulus-evoked mucus secretion in cystic fibrosis bronchi. Exp Lung Res (1993) 0.81

Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels. Respir Res (2014) 0.81

Smoking and COPD increase sputum levels of extracellular superoxide dismutase. Free Radic Biol Med (2011) 0.80

Morphological analysis of the trachea and pattern of breathing in βENaC-Tg mice. Respir Physiol Neurobiol (2011) 0.77

Nonhuman Primate IFITM Proteins Are Potent Inhibitors of HIV and SIV. PLoS One (2016) 0.78