Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome.

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Published in World J Gastroenterol on October 21, 2014

Authors

Carly E Kelley1, Ann J Brown1, Anna Mae Diehl1, Tracy L Setji1

Author Affiliations

1: Carly E Kelley, Ann J Brown, Tracy L Setji, Department of Medicine, Division of Endocrinology, Duke University Medical Center, Durham, NC 27710, United States.

Associated clinical trials:

The Farnesoid X Receptor (FXR) Ligand Obeticholic Acid in NASH Treatment Trial(FLINT) (FLINT) | NCT01265498

Spironolactone Therapy In Young Women With NASH | NCT03576755

Saroglitazar Magnesium 4 mg in the Treatment of NAFLD in Women With PCOS (EVIDENCES VII) | NCT03617263

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Nonalcoholic fatty liver disease. N Engl J Med (2002) 22.41

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Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril (2004) 12.87

Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology (1999) 11.76

The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology (2012) 11.03

Updated definitions of healthy ranges for serum alanine aminotransferase levels. Ann Intern Med (2002) 10.78

Thiazolidinediones. N Engl J Med (2004) 9.42

Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology (2006) 9.34

The prevalence and etiology of elevated aminotransferase levels in the United States. Am J Gastroenterol (2003) 8.23

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Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment Pharmacol Ther (2011) 7.91

Nonalcoholic steatohepatitis. Ann Intern Med (1997) 5.74

Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study. Hepatology (2009) 4.82

Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an Androgen Excess Society guideline. J Clin Endocrinol Metab (2006) 4.56

NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology (2002) 4.44

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The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Hum Reprod (2009) 3.74

Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes (1989) 3.74

The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology (1995) 3.73

The Fatty Liver Index: a simple and accurate predictor of hepatic steatosis in the general population. BMC Gastroenterol (2006) 3.62

Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: present and future. Hepatology (2007) 3.58

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Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. JAMA (2011) 3.37

The natural history of nonalcoholic fatty liver disease: a clinical histopathological study. Am J Gastroenterol (2003) 3.04

Increased overall mortality and liver-related mortality in non-alcoholic fatty liver disease. J Hepatol (2008) 2.87

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Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab (2013) 2.43

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Omega-3 supplementation and non-alcoholic fatty liver disease: a systematic review and meta-analysis. J Hepatol (2011) 2.24

Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999-2004. Gastroenterology (2007) 2.22

Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med (2010) 2.21

Nonalcoholic fatty liver disease: assessment of variability in pathologic interpretations. Mod Pathol (1998) 2.13

Factors associated with serum alanine transaminase activity in healthy subjects: consequences for the definition of normal values, for selection of blood donors, and for patients with chronic hepatitis C. MULTIVIRC Group. Hepatology (1998) 2.08

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Androgen receptor-mediated antagonism of estrogen-dependent low density lipoprotein receptor transcription in cultured hepatocytes. Endocrinology (1997) 0.93

Hyperinsulinemia in hyperthecosis of the ovaries. Am J Obstet Gynecol (1986) 0.92

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Apoptotic markers indicate nonalcoholic steatohepatitis in polycystic ovary syndrome. J Clin Endocrinol Metab (2009) 0.87

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Abnormal aminotransferase activity in women with polycystic ovary syndrome. Fertil Steril (2005) 0.87

Phenotypes and enviromental factors: their influence in PCOS. Curr Pharm Des (2012) 0.86