Immune characterization of Plasmodium falciparum parasites with a shared genetic signature in a region of decreasing transmission.

High Plasmodium falciparum longitudinal prevalence is associated with high multiclonality and reduced clinical malaria risk in a seasonal transmission area of Mali. PLoS One (2017) 0.75

Simulating within-vector generation of the malaria parasite diversity. PLoS One (2017) 0.75

Basic local alignment search tool. J Mol Biol (1990) 659.07

MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Res (2004) 168.89

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol (2010) 75.21

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol (2013) 32.42

The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature (2005) 31.73

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics (2011) 25.76

Global malaria mortality between 1980 and 2010: a systematic analysis. Lancet (2012) 17.62

Differential analysis of gene regulation at transcript resolution with RNA-seq. Nat Biotechnol (2012) 14.01

De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis. Nat Protoc (2013) 13.33

Gamma-globulin and acquired immunity to human malaria. Nature (1961) 13.07

Estimating mortality, morbidity and disability due to malaria among Africa's non-pregnant population. Bull World Health Organ (1999) 12.10

Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes. Cell (1995) 9.31

RobiNA: a user-friendly, integrated software solution for RNA-Seq-based transcriptomics. Nucleic Acids Res (2012) 7.48

Acquired immunity to malaria. Clin Microbiol Rev (2009) 6.24

Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria. Nat Med (1998) 5.41

Antibodies that protect humans against Plasmodium falciparum blood stages do not on their own inhibit parasite growth and invasion in vitro, but act in cooperation with monocytes. J Exp Med (1990) 5.04

P. falciparum rosetting mediated by a parasite-variant erythrocyte membrane protein and complement-receptor 1. Nature (1997) 4.84

Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infection. Trans R Soc Trop Med Hyg (1990) 4.70

Antigenic variation at the infected red cell surface in malaria. Annu Rev Microbiol (2001) 4.12

Phase 1 clinical trial of apical membrane antigen 1: an asexual blood-stage vaccine for Plasmodium falciparum malaria. Infect Immun (2005) 3.72

Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes. J Exp Med (2004) 3.63

Antigens induced on erythrocytes by P. falciparum: expression of diverse and conserved determinants. Science (1986) 3.47

Detection of antibodies to variant antigens on Plasmodium falciparum-infected erythrocytes by flow cytometry. Cytometry (1999) 2.87

Severe malaria is associated with parasite binding to endothelial protein C receptor. Nature (2013) 2.86

Identification of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) as the rosetting ligand of the malaria parasite P. falciparum. J Exp Med (1998) 2.83

Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer. PLoS Comput Biol (2010) 2.80

A general SNP-based molecular barcode for Plasmodium falciparum identification and tracking. Malar J (2008) 2.54

Plasmodium falciparum clearance rates in response to artesunate in Malian children with malaria: effect of acquired immunity. J Infect Dis (2013) 2.47

Plasmodium falciparum-infected erythrocytes: agglutination by diverse Kenyan plasma is associated with severe disease and young host age. J Infect Dis (2000) 2.35

Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia. Mol Biochem Parasitol (2006) 2.22

Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian children. Infect Immun (2006) 2.16

Antigenic variation in Plasmodium falciparum. Proc Natl Acad Sci U S A (1991) 2.13

Plasmodium falciparum variant surface antigen expression patterns during malaria. PLoS Pathog (2005) 2.13

Target antigens of purified human immunoglobulins which inhibit growth of Plasmodium falciparum in vitro. Nature (1982) 2.11

Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies. J Clin Invest (2008) 1.96

Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infections. Immunol Lett (2000) 1.89

Var gene diversity in Plasmodium falciparum is generated by frequent recombination events. Mol Biochem Parasitol (2000) 1.67

Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family. PLoS Pathog (2011) 1.53

Heparan sulfate on endothelial cells mediates the binding of Plasmodium falciparum-infected erythrocytes via the DBL1alpha domain of PfEMP1. Blood (2002) 1.51

PfEMP1-DBL1alpha amino acid motifs in severe disease states of Plasmodium falciparum malaria. Proc Natl Acad Sci U S A (2007) 1.47

Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adults. PLoS One (2008) 1.46

Genetic surveillance detects both clonal and epidemic transmission of malaria following enhanced intervention in Senegal. PLoS One (2013) 1.40

In vitro growth-inhibitory activity and malaria risk in a cohort study in mali. Infect Immun (2009) 1.39

Recent insights into humoral and cellular immune responses against malaria. Trends Parasitol (2008) 1.39

Comparison of biological activity of human anti-apical membrane antigen-1 antibodies induced by natural infection and vaccination. J Immunol (2008) 1.34

Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity. J Clin Invest (2012) 1.31

Immune responses to asexual blood-stages of malaria parasites. Curr Mol Med (2006) 1.28

Analysis of Plasmodium falciparum var genes expressed in children from Papua New Guinea. J Infect Dis (2009) 1.20

Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children. Int J Parasitol (2008) 1.14

Differential changes in Plasmodium falciparum var transcription during adaptation to culture. J Infect Dis (2007) 1.04

Erasing the epigenetic memory and beginning to switch--the onset of antigenic switching of var genes in Plasmodium falciparum. PLoS One (2012) 0.97

A network approach to analyzing highly recombinant malaria parasite genes. PLoS Comput Biol (2013) 0.97

Reevaluation of flow cytometry for investigating antibody binding to the surface of Plasmodium falciparum trophozoite-infected red blood cells. Cytometry A (2003) 0.94

Effects of age, hemoglobin type and parasite strain on IgG recognition of Plasmodium falciparum-infected erythrocytes in Malian children. PLoS One (2013) 0.82

Population genomics studies identify signatures of global dispersal and drug resistance in Plasmodium vivax. Nat Genet (2016) 0.93

An adjustable gas-mixing device to increase feasibility of in vitro culture of Plasmodium falciparum parasites in the field. PLoS One (2014) 0.76

Functional analysis reveals geographical variation in inhibitory immune responses against a polymorphic malaria antigen. J Infect Dis (2017) 0.75

Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity: The West African Merozoite Invasion Network (WAMIN). Trends Parasitol (2015) 0.75