Individually tailored screening of susceptibility to sarcopenia using p53 codon 72 polymorphism, phenotypes, and conventional risk factors.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 4211310)

Published in Dis Markers on October 13, 2014

Authors

Laura Di Renzo1, Santo Gratteri2, Francesca Sarlo3, Andrea Cabibbo4, Carmen Colica5, Antonino De Lorenzo6

Author Affiliations

1: Department of Biomedicine and Prevention, Division of Clinical Nutrition and Nutrigenomics, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy ; Nuova Clinica Annunziatella, 00147 Roma, Italy.
2: Department of Surgery and Medical Science, University "Magna Graecia", 88100 Germaneto, Italy.
3: Department of Agriculture, University of Naples "Federico II", 80055 Portici, Italy.
4: Department of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.
5: CNR, ISN UOS of Pharmacology, Department of Pharmacology, University "Magna Graecia", 88100 Roccelletta di Borgia, Italy.
6: Section of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00136 Roma, Italy ; National Institute for Mediterranean Diet and Nutrigenomics (I.N.Di.M.), Corso Vittorio Emanuele 4, 87032 Amantea, Italy.

Associated clinical trials:

Study of the Nutraceutical Properties and Health Benefits of Traditional Components of the Mediterranean Diet | NCT01890070

Articles citing this

New obesity classification criteria as a tool for bariatric surgery indication. World J Gastroenterol (2016) 0.80

Articles cited by this

Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser (2000) 70.59

Surfing the p53 network. Nature (2000) 35.36

Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing (2010) 17.45

Estimating the population attributable risk for multiple risk factors using case-control data. Am J Epidemiol (1985) 11.38

p53 in health and disease. Nat Rev Mol Cell Biol (2007) 11.33

p53 mutant mice that display early ageing-associated phenotypes. Nature (2002) 10.05

Waist circumference and not body mass index explains obesity-related health risk. Am J Clin Nutr (2004) 8.87

Systems biology and new technologies enable predictive and preventative medicine. Science (2004) 7.59

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways. Nat Cell Biol (2001) 6.71

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science (1995) 6.01

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase. Nature (1998) 4.89

Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry method. Am J Clin Nutr (2002) 2.96

Defining the regulatory networks for muscle development. Curr Opin Genet Dev (1996) 2.79

Comparisons of waist circumferences measured at 4 sites. Am J Clin Nutr (2003) 2.78

Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality. Eur Heart J (2009) 2.71

Regional differences in cellular mechanisms of adipose tissue gain with overfeeding. Proc Natl Acad Sci U S A (2010) 2.17

Intracellular signaling during skeletal muscle atrophy. Muscle Nerve (2006) 2.13

Systems cancer medicine: towards realization of predictive, preventive, personalized and participatory (P4) medicine. J Intern Med (2012) 2.13

Normal-weight obese syndrome: early inflammation? Am J Clin Nutr (2007) 2.10

Skeletal muscle loss: cachexia, sarcopenia, and inactivity. Am J Clin Nutr (2010) 2.04

Subcutaneous adipocyte size and body fat distribution. Am J Clin Nutr (2008) 1.80

AccII polymorphism of the p53 gene. Nucleic Acids Res (1990) 1.80

Catabolism of aging: is it an inflammatory process? Curr Opin Clin Nutr Metab Care (2003) 1.64

Maximal extraction of biological information from genetic interaction data. PLoS Comput Biol (2009) 1.42

Molecular and cellular mechanisms of skeletal muscle atrophy: an update. J Cachexia Sarcopenia Muscle (2012) 1.40

Obesity, metabolic syndrome, and type 2 diabetes: emerging epidemics and their cardiovascular implications. Cardiol Clin (2004) 1.32

The concept of normal weight obesity. Prog Cardiovasc Dis (2013) 1.29

p53 regulates myogenesis by triggering the differentiation activity of pRb. J Cell Biol (2000) 1.25

Normal weight obese (NWO) women: an evaluation of a candidate new syndrome. Nutr Metab Cardiovasc Dis (2006) 1.17

Intramuscular adipose tissue, sarcopenia, and mobility function in older individuals. J Aging Res (2012) 1.16

Body composition and its association with cardiometabolic risk factors in the elderly: a focus on sarcopenic obesity. Arch Gerontol Geriatr (2012) 1.14

Adiposity rather than BMI determines metabolic risk. Int J Cardiol (2011) 1.09

Role of the Crosstalk between Autophagy and Apoptosis in Cancer. J Oncol (2013) 1.07

Increased nuclear proteins in muscle satellite cells in aged animals as compared to young growing animals. Exp Gerontol (2004) 1.04

Differential levels of transcription of p53-regulated genes by the arginine/proline polymorphism: p53 with arginine at codon 72 favors apoptosis. FASEB J (2009) 0.99

Prevalence of sarcopenia based on different diagnostic criteria using DEXA and appendicular skeletal muscle mass reference values in an Italian population aged 20 to 80. J Am Med Dir Assoc (2013) 0.98

Obesity genes and gene-environment-behavior interactions: recommendations for a way forward. Obesity (Silver Spring) (2008) 0.97

Oxidative stress in normal-weight obese syndrome. Obesity (Silver Spring) (2010) 0.95

Normal weight obesity is associated with metabolic syndrome and insulin resistance in young adults from a middle-income country. PLoS One (2013) 0.94

Women's higher health risks in the obesogenic environment: a gender nutrition approach to metabolic dimorphism with predictive, preventive, and personalised medicine. EPMA J (2013) 0.94

The role of wild-type p53 in the differentiation of primary hemopoietic and muscle cells. Oncogene (1999) 0.93

Systems pharmacology meets predictive, preventive, personalized and participatory medicine. Pharmacogenomics (2013) 0.93

Body composition and -174G/C interleukin-6 promoter gene polymorphism: association with progression of insulin resistance in normal weight obese syndrome. Curr Pharm Des (2008) 0.92

Normal Weight Obese syndrome: role of single nucleotide polymorphism of IL-1 5Ralpha and MTHFR 677C-->T genes in the relationship between body composition and resting metabolic rate. Eur Rev Med Pharmacol Sci (2006) 0.91

SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53. PLoS One (2010) 0.89

Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time. Eur J Hum Genet (2011) 0.89

Body composition analyses in normal weight obese women. Eur Rev Med Pharmacol Sci (2006) 0.87

Interleukin-1 (IL-1) receptor antagonist gene polymorphism in normal weight obese syndrome: relationship to body composition and IL-1 alpha and beta plasma levels. Pharmacol Res (2006) 0.86

Mechanisms of muscle wasting in sarcopenia. Rev Bras Reumatol (2012) 0.85

Prevalence of normal weight obesity in Switzerland: effect of various definitions. Eur J Nutr (2008) 0.85

Subclinical vascular inflammation in subjects with normal weight obesity and its association with body fat: an 18 F-FDG-PET/CT study. Cardiovasc Diabetol (2014) 0.85

Increased Plin2 expression in human skeletal muscle is associated with sarcopenia and muscle weakness. PLoS One (2013) 0.82

Association of body composition with sarcopenic obesity in elderly women. Int J Gen Med (2013) 0.81

A new predictive equation for evaluating women body fat percentage and obesity-related cardiovascular disease risk. J Endocrinol Invest (2014) 0.79

The p53 Codon 72 Polymorphism Modifies the Cellular Response to Inflammatory Challenge in the Liver. J Liver (2013) 0.79

Predicting the influence of multiple components on microbial inhibition using a logistic response model--a novel approach. BMC Complement Altern Med (2014) 0.78

Gene expression profiles resulting from stable loss of p53 mirrors its role in tissue differentiation. PLoS One (2013) 0.76