Mutations in HIV-1 envelope that enhance entry with the macaque CD4 receptor alter antibody recognition by disrupting quaternary interactions within the trimer.

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Published in J Virol on November 05, 2014

Authors

David F Boyd1, Dylan Peterson2, Beth S Haggarty3, Andrea P O Jordan3, Michael J Hogan3, Leslie Goo1, James A Hoxie3, Julie Overbaugh4

Author Affiliations

1: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA Pathobiology Graduate Program, University of Washington, Seattle, Washington, USA.
2: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
3: Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
4: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA joverbau@fhcrc.org.

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