Published in Oxid Med Cell Longev on October 14, 2014
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Free radicals and antioxidants: updating a personal view. Nutr Rev (2012) 1.95
The redox chemistry of the Alzheimer's disease amyloid beta peptide. Biochim Biophys Acta (2007) 1.83
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Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage. Biochem Biophys Res Commun (1997) 1.53
A detailed analysis of hydrogen peroxide-induced cell death in primary neuronal culture. Neuroscience (1995) 1.50
Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. PLoS One (2009) 1.46
Extended culture of mouse embryo cells without senescence: inhibition by serum. Science (1987) 1.43
Bioimaging of nitric oxide with fluorescent indicators based on the rhodamine chromophore. Anal Chem (2001) 1.42
Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity. Biochim Biophys Acta (2011) 1.40
Transport of drugs across the blood-brain barrier by nanoparticles. J Control Release (2011) 1.37
Redox regulation of mitochondrial function with emphasis on cysteine oxidation reactions. Redox Biol (2013) 1.28
Neurodegeneration as a consequence of failed mitochondrial maintenance. Acta Neuropathol (2011) 1.28
Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity. Mol Aspects Med (2011) 1.27
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Flow cytometric measurement of cytoplasmic free calcium in human peripheral blood T lymphocytes with fluo-3, a new fluorescent calcium indicator. J Immunol Methods (1990) 1.23
Mitochondrial medicine for aging and neurodegenerative diseases. Neuromolecular Med (2008) 1.22
Kinetic analysis of superoxide anion radical-scavenging and hydroxyl radical-scavenging activities of platinum nanoparticles. Langmuir (2008) 1.21
Effects of a potent antioxidant, platinum nanoparticle, on the lifespan of Caenorhabditis elegans. Mech Ageing Dev (2008) 1.18
Platinum nanoparticle is a useful scavenger of superoxide anion and hydrogen peroxide. Free Radic Res (2007) 1.14
Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA. Mol Aspects Med (2011) 1.14
Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease. Free Radic Res (2011) 1.13
Changes in mitochondrial membrane potential during oxidative stress-induced apoptosis in PC12 cells. J Neurosci Res (1997) 1.12
Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations. Arch Toxicol (2011) 1.10
Oxidative stress in neurodegeneration. Adv Pharmacol Sci (2011) 1.09
Extension of the lifespan of Caenorhabditis elegans by the use of electrolyzed reduced water. Biosci Biotechnol Biochem (2010) 1.08
Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes. Neurochem Res (2006) 1.07
Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage: Scavenging effect against reactive oxygen species. Cytotechnology (2002) 1.07
Molecular hydrogen reduces LPS-induced neuroinflammation and promotes recovery from sickness behaviour in mice. PLoS One (2012) 1.03
Increase in external glutamate and NMDA receptor activation contribute to H2O2-induced neuronal apoptosis. J Neurochem (1999) 1.02
Cellular uptake of platinum nanoparticles in human colon carcinoma cells and their impact on cellular redox systems and DNA integrity. Chem Res Toxicol (2009) 0.99
Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice. Food Chem Toxicol (2009) 0.98
Effects of cytosine arabinoside, daunomycin, mithramycin, azacytidine, adriamycin, and camptothecin on mammalian cell cycle traverse. Cancer Res (1972) 0.98
Suppressive effects of electrolyzed reduced water on alloxan-induced apoptosis and type 1 diabetes mellitus. Cytotechnology (2010) 0.98
Yokukansan, a kampo medicine, protects against glutamate cytotoxicity due to oxidative stress in PC12 cells. J Ethnopharmacol (2010) 0.98
Oxidative damage to RNA in neurodegenerative diseases. J Biomed Biotechnol (2006) 0.96
Characterization of 2',7'-dichlorofluorescin fluorescence in dissociated mammalian brain neurons: estimation on intracellular content of hydrogen peroxide. Brain Res (1994) 0.95
In vitro techniques for the assessment of neurotoxicity. Environ Health Perspect (1998) 0.95
Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water. Kidney Int (2003) 0.94
Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis. Med Sci Monit (2012) 0.93
Epigallocatechin gallate inhibits nitric oxide-induced apoptosis in rat PC12 cells. Neurosci Lett (2006) 0.92
Neuroprotective effect of ginkgolide K on glutamate-induced cytotoxicity in PC 12 cells via inhibition of ROS generation and Ca(2+) influx. Neurotoxicology (2011) 0.91
Inhibitory effect of electrolyzed reduced water on tumor angiogenesis. Biol Pharm Bull (2008) 0.89
Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: Mitochondria as a "chi". Immun Ageing (2013) 0.89
SOD/catalase mimetic platinum nanoparticles inhibit heat-induced apoptosis in human lymphoma U937 and HH cells. Free Radic Res (2010) 0.86
Strong neuroprotection with a novel platinum nanoparticle against ischemic stroke- and tissue plasminogen activator-related brain damages in mice. Neuroscience (2012) 0.86
Cellular stress response, redox status, and vitagenes in glaucoma: a systemic oxidant disorder linked to Alzheimer's disease. Front Pharmacol (2014) 0.85
Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes. Immun Ageing (2013) 0.85
Challenges in drug delivery to the brain: nature is against us. J Control Release (2012) 0.84
Electrolysed-reduced water dialysate improves T-cell damage in end-stage renal disease patients with chronic haemodialysis. Nephrol Dial Transplant (2010) 0.84
Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes. J Photochem Photobiol B (2011) 0.84
Differentiation of neuroblastoma cell line N1E-115 involves several signaling cascades. Neurochem Res (2005) 0.83
Sodium nitroprusside-induced apoptotic cellular death via production of hydrogen peroxide in murine neuroblastoma N1E-115 cells. J Pharmacol Toxicol Methods (1996) 0.83
Electrolyzed hydrogen-saturated water for drinking use elicits an antioxidative effect: a feeding test with rats. Biosci Biotechnol Biochem (2005) 0.83
Reactive oxygen species in NMDA receptor-mediated glutamate neurotoxicity. Parkinsonism Relat Disord (1999) 0.82
Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water--participation of Pt nanoparticles. Biosci Biotechnol Biochem (2011) 0.82
Increased vulnerability of neuronal cell lines to sodium nitroprusside-mediated toxicity is caused by the decreased level of nitric oxide metabolites. J Mol Neurosci (2000) 0.82
Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice. Biol Pharm Bull (2007) 0.81
Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells. Free Radic Res (2011) 0.80
Proteins involved in neuronal differentiation of neuroblastoma cell line N1E-115. Electrophoresis (2007) 0.79
Serum-free mouse embryo cells generate a self-sustaining feedback loop for an astrocyte marker protein and respond to cytokines and bisphenol A in accordance with the subtle difference in their differentiation state. Cell Biol Int (2006) 0.79
Anti-diabetes effect of water containing hydrogen molecule and Pt nanoparticles. BMC Proc (2011) 0.79
Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth. Eur J Pharm Sci (2011) 0.79
Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells due to electrolyzed-reduced water and glutathione. Biosci Biotechnol Biochem (2009) 0.79
An ultrastructural study of cortical remodeling in cytosine arabinoside induced granuloprival cerebellum in tissue culture. Neuroscience (1982) 0.79
Endogenous factors regulating neuronal death induced by radical stress. Biol Pharm Bull (2004) 0.78
The neuroprotective effects of electrolyzed reduced water and its model water containing molecular hydrogen and Pt nanoparticles. BMC Proc (2011) 0.78
Suppressive effects of electrochemically reduced water on matrix metalloproteinase-2 activities and in vitro invasion of human fibrosarcoma HT1080 cells. Cytotechnology (2012) 0.78
Identification of a rapidly dephosphorylating 95-kDa protein as elongation factor 2 during 8-Br-cAMP treatment of N1E115 neuroblastoma cells. Biochem Biophys Res Commun (1995) 0.76