Quantitative assessment of barriers to the clinical development and adoption of cellular therapies: A pilot study.

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🔗 View Article (PMC 4221931)

Published in J Tissue Eng on September 19, 2014

Authors

Benjamin M Davies¹, Sarah Rikabi¹, Anna French², Rafael Pinedo-Villanueva³, Mark E Morrey⁴, Karolina Wartolowska¹, Andrew Judge³, Robert E MacLaren⁵, Anthony Mathur⁶, David J Williams⁷, Ivan Wall⁸, Martin Birchall⁹, Brock Reeve¹⁰, Anthony Atala¹¹, Richard W Barker², Zhanfeng Cui¹², Dominic Furniss¹, Kim Bure¹³, Evan Y Snyder¹⁴, Jeffrey M Karp¹⁵, Andrew Price¹, Andrew Carr¹⁶, David A Brindley¹⁷

Author Affiliations

1: Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
2: The Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation (CASMI), University of Oxford, Oxford, UK.
3: Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK ; MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, UK.
4: Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
5: Nuffield Laboratory of Ophthalmology, University of Oxford, Oxford, UK.
6: NIHR Cardiovascular Biomedical Research Unit, London Chest Hospital, London, UK ; Department of Cardiology, Barts Health NHS Trust, London, UK ; Department of Clinical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London, UK.
7: Centre for Biological Engineering, Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, Loughborough, UK.
8: Department of Biochemical Engineering, University College London, London, UK ; Department of Nanobiomedical Science & BK21 Plus NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, Republic of Korea ; Biomaterials and Tissue Engineering Lab, Department of Nanobiomedical Science and WCU Research Center, Dankook University, Cheonan, Republic of Korea.
9: The Ear Institute, University College London, London, UK.
10: Harvard Stem Cell Institute, Cambridge, MA, USA.
11: Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
12: Oxford Centre for Tissue Engineering and Bioprocessing, University of Oxford, Oxford, UK.
13: Sartorius Stedim, Göttingen, Germany.
14: Sanford-Burnham Medical Research Institute, La Jolla, CA, USA ; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA ; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.
15: Harvard Stem Cell Institute, Cambridge, MA, USA ; Division of Biomedical Engineering, Department of Medicine, Center for Regenerative Therapeutics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA ; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA ; Harvard Medical School, Cambridge, MA, USA.
16: Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK ; The Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation (CASMI), University of Oxford, Oxford, UK.
17: Botnar Research Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK ; The Oxford-UCL Centre for the Advancement of Sustainable Medical Innovation (CASMI), University of Oxford, Oxford, UK ; Harvard Stem Cell Institute, Cambridge, MA, USA ; Centre for Behavioural Medicine, UCL School of Pharmacy, University College London, London, UK.