The effects of phenoxodiol on the cell cycle of prostate cancer cell lines.

PubWeight™: 0.78‹?›

🔗 View Article (PMC 4231195)

Published in Cancer Cell Int on November 08, 2014

Authors

Simon Mahoney1, Frank Arfuso2, Michael Millward3, Arun Dharmarajan2

Author Affiliations

1: School of Anatomy, Physiology and Human Biology, Faculty of Science, The University of Western Australia, Crawley, Perth, WA 6009 Australia.
2: School of Anatomy, Physiology and Human Biology, Faculty of Science, The University of Western Australia, Crawley, Perth, WA 6009 Australia ; Curtin Health Innovation Research Institute, Biosciences Research Precinct, School of Biomedical Sciences, Faculty of Health Sciences, Curtin University, GPO Box U1987, 6845 Perth, WA Australia.
3: School of Medicine and Pharmacology, The University of Western Australia, Crawley, Perth, WA 6009 Australia.

Articles cited by this

Hallmarks of cancer: the next generation. Cell (2011) 140.01

The hallmarks of cancer. Cell (2000) 113.05

WAF1, a potential mediator of p53 tumor suppression. Cell (1993) 38.72

A restriction point for control of normal animal cell proliferation. Proc Natl Acad Sci U S A (1974) 8.74

Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev (1993) 8.03

Minireview: Cyclin D1: normal and abnormal functions. Endocrinology (2004) 5.22

Docetaxel for treatment of solid tumours: a systematic review of clinical data. Lancet Oncol (2005) 1.59

Cyclins, cyclin-dependent kinases and cdk inhibitors: implications in cell cycle control and cancer. Crit Rev Eukaryot Gene Expr (1995) 1.58

p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells. Mol Cancer Ther (2007) 1.40

Reappraisal of serum starvation, the restriction point, G0, and G1 phase arrest points. FASEB J (2003) 1.38

Linkage of curcumin-induced cell cycle arrest and apoptosis by cyclin-dependent kinase inhibitor p21(/WAF1/CIP1). Cell Cycle (2007) 1.30

Regulation of exit from quiescence by p27 and cyclin D1-CDK4. Mol Cell Biol (1998) 1.26

Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis. Cell Death Dis (2011) 1.15

Resistance to docetaxel-induced apoptosis in prostate cancer cells by p38/p53/p21 signaling. Prostate (2011) 1.07

Myc: the beauty and the beast. Genes Cancer (2010) 1.07

Impairment of the DNA repair and growth arrest pathways by p53R2 silencing enhances DNA damage-induced apoptosis in a p53-dependent manner in prostate cancer cells. Mol Cancer Res (2008) 1.06

Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype. Cell Cycle (2008) 1.01

Risks and benefits of taxanes in breast and ovarian cancer. Drug Saf (2000) 0.99

Targeting cell cycle and apoptosis for the treatment of human malignancies. Curr Opin Cell Biol (2004) 0.98

Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells. Mol Cell Biol (2011) 0.97

Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1. Cancer Res (2005) 0.96

GATA3 in the urinary bladder: suppression of neoplastic transformation and down-regulation by androgens. Am J Cancer Res (2014) 0.93

Phenoxodiol (2H-1-benzopyran-7-0,1,3-(4-hydroxyphenyl)), a novel isoflavone derivative, inhibits DNA topoisomerase II by stabilizing the cleavable complex. Anticancer Res (2003) 0.91

Bortezomib inhibits docetaxel-induced apoptosis via a p21-dependent mechanism in human prostate cancer cells. Mol Cancer Ther (2006) 0.88

p21WAF1/CIP1 gene is inactivated in metastatic prostatic cancer cell lines by promoter methylation. Prostate Cancer Prostatic Dis (2005) 0.87

Apoptotic effects of genistein, biochanin-A and apigenin on LNCaP and PC-3 cells by p21 through transcriptional inhibition of polo-like kinase-1. J Korean Med Sci (2011) 0.85

Phenoxodiol inhibits growth of metastatic prostate cancer cells. Prostate (2010) 0.84

Targeted cancer therapy: what if the driver is just a messenger? Cell Cycle (2011) 0.82

The effect of chemotherapy on Ki-67, Bcl-2 and Bak expression in primary tumors and lymph node metastases of breast cancer. Oncol Rep (2007) 0.82

Frequency of Ki-67 (MIB-1) and P53 expressions among patients with prostate cancer. Indian J Pathol Microbiol (2012) 0.82

Cytotoxic effects of the novel isoflavone, phenoxodiol, on prostate cancer cell lines. J Biosci (2012) 0.81

Phenoxodiol treatment alters the subsequent response of ENOX2 (tNOX) and growth of hela cells to paclitaxel and cisplatin. Mol Biotechnol (2009) 0.79

A mimic of phosphorylated prolactin inhibits human breast cancer cell proliferation via upregulation of p21 waf1. Med Oncol (2009) 0.77