Published in Biophys J on November 04, 2014
CHARMM-GUI HMMM Builder for Membrane Simulations with the Highly Mobile Membrane-Mimetic Model. Biophys J (2015) 0.87
Efficient Exploration of Membrane-Associated Phenomena at Atomic Resolution. J Membr Biol (2015) 0.87
A highly tilted membrane configuration for the prefusion state of synaptobrevin. Biophys J (2014) 0.86
Atomic-level description of protein-lipid interactions using an accelerated membrane model. Biochim Biophys Acta (2016) 0.81
Capturing Spontaneous Membrane Insertion of the Influenza Virus Hemagglutinin Fusion Peptide. J Phys Chem B (2015) 0.80
Incorporation of charged residues in the CYP2J2 F-G loop disrupts CYP2J2-lipid bilayer interactions. Biochim Biophys Acta (2015) 0.80
Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed in Atomic Detail. Biochemistry (2016) 0.77
Phospholipase C and D regulation of Src, calcium release and membrane fusion during Xenopus laevis development. Dev Biol (2015) 0.76
The cellular membrane as a mediator for small molecule interaction with membrane proteins. Biochim Biophys Acta (2016) 0.75
Lipid Specificity of the Membrane Binding Domain of Coagulation Factor X. J Thromb Haemost (2017) 0.75
Coupling X-Ray Reflectivity and In Silico Binding to Yield Dynamics of Membrane Recognition by Tim1. Biophys J (2017) 0.75
The Integrin Receptor in Biologically Relevant Bilayers: Insights from Molecular Dynamics Simulations. J Membr Biol (2016) 0.75
Extension of the Highly Mobile Membrane Mimetic to Transmembrane Systems through Customized in Silico Solvents. J Phys Chem B (2017) 0.75
VMD: visual molecular dynamics. J Mol Graph (1996) 117.02
Scalable molecular dynamics with NAMD. J Comput Chem (2005) 59.49
Integrins: bidirectional, allosteric signaling machines. Cell (2002) 36.25
Extending the treatment of backbone energetics in protein force fields: limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations. J Comput Chem (2004) 17.97
CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields. J Comput Chem (2010) 8.79
Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types. J Phys Chem B (2010) 8.70
Talin binding to integrin beta tails: a final common step in integrin activation. Science (2003) 7.56
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science (2003) 5.58
Structural basis of integrin activation by talin. Cell (2007) 5.37
The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation. J Biol Chem (1999) 4.92
The final steps of integrin activation: the end game. Nat Rev Mol Cell Biol (2010) 4.72
The tail of integrins, talin, and kindlins. Science (2009) 4.51
Imaging alpha-hemolysin with molecular dynamics: ionic conductance, osmotic permeability, and the electrostatic potential map. Biophys J (2005) 4.45
Structural determinants of integrin recognition by talin. Mol Cell (2003) 4.20
A new protein of adhesion plaques and ruffling membranes. J Cell Biol (1983) 3.88
Integrin regulation. Curr Opin Cell Biol (2005) 3.80
The nature of the hydrophobic binding of small peptides at the bilayer interface: implications for the insertion of transbilayer helices. Biochemistry (1989) 3.71
The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor. Nature (1996) 3.40
Sequence and domain structure of talin. Nature (1990) 2.98
The phosphotyrosine binding-like domain of talin activates integrins. J Biol Chem (2002) 2.97
The structure of an integrin/talin complex reveals the basis of inside-out signal transduction. EMBO J (2009) 2.76
Biochemical and structural properties of the integrin-associated cytoskeletal protein talin. Annu Rev Biophys (2009) 2.47
Structural biology. Proton-powered turbine of a plant motor. Nature (2000) 2.40
Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides. J Biol Chem (2001) 2.25
The Structure of the talin head reveals a novel extended conformation of the FERM domain. Structure (2010) 2.22
Insertion and assembly of membrane proteins via simulation. J Am Chem Soc (2006) 2.12
Structure and fluctuations of charged phosphatidylserine bilayers in the absence of salt. Biophys J (2004) 2.08
Integrin activation takes shape. J Cell Biol (2002) 2.02
Four-scale description of membrane sculpting by BAR domains. Biophys J (2008) 2.00
Crystal structure of human factor VIII: implications for the formation of the factor IXa-factor VIIIa complex. Structure (2008) 1.93
The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins. J Biol Chem (2007) 1.89
Amphitropic proteins: regulation by reversible membrane interactions (review). Mol Membr Biol (1999) 1.76
Interfacial folding and membrane insertion of designed peptides studied by molecular dynamics simulations. Proc Natl Acad Sci U S A (2005) 1.66
Platelet integrin alpha(IIb)beta(3): activation mechanisms. J Thromb Haemost (2007) 1.63
Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP. J Mol Biol (1991) 1.59
New PI(4,5)P2- and membrane proximal integrin-binding motifs in the talin head control beta3-integrin clustering. J Cell Biol (2009) 1.58
Snorkeling of lysine side chains in transmembrane helices: how easy can it get? FEBS Lett (2003) 1.57
Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation. EMBO J (2010) 1.45
Interactions of synthetic peptide analogs of the class A amphipathic helix with lipids. Evidence for the snorkel hypothesis. J Biol Chem (1994) 1.39
Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review). Mol Membr Biol (2008) 1.39
Distinct structural and adhesive roles of Ca2+ in membrane binding of blood coagulation factors. Structure (2008) 1.33
Integrin structure: heady advances in ligand binding, but activation still makes the knees wobble. Trends Biochem Sci (2003) 1.30
Mixed atomistic and coarse-grained molecular dynamics: simulation of a membrane-bound ion channel. J Phys Chem B (2006) 1.29
Thermodynamics and kinetics of protein incorporation into membranes. Proc Natl Acad Sci U S A (1983) 1.24
A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion. Cell Res (2012) 1.24
Membrane assembly of simple helix homo-oligomers studied via molecular dynamics simulations. Biophys J (2006) 1.23
The talin-tail interaction places integrin activation on FERM ground. Trends Biochem Sci (2004) 1.22
Combinatorial antibody libraries from cancer patients yield ligand-mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis. Proc Natl Acad Sci U S A (2004) 1.21
Structural diversity in integrin/talin interactions. Structure (2010) 1.20
Integrin activation by talin. J Thromb Haemost (2005) 1.19
The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study. Structure (2010) 1.14
Lipid-protein interactions of integral membrane proteins: a comparative simulation study. Biophys J (2004) 1.12
Accelerating membrane insertion of peripheral proteins with a novel membrane mimetic model. Biophys J (2012) 1.08
Multiscale simulations suggest a mechanism for integrin inside-out activation. Proc Natl Acad Sci U S A (2011) 1.00
Interaction of the 47-kDa talin fragment and the 32-kDa vinculin fragment with acidic phospholipids: a computer analysis. Biophys J (1995) 0.97
Capturing spontaneous partitioning of peripheral proteins using a biphasic membrane-mimetic model. J Phys Chem B (2011) 0.95
Peptide-specific antibodies localize the major lipid binding sites of talin dimers to oppositely arranged N-terminal 47 kDa subdomains. FEBS Lett (1998) 0.92
Interaction of NBD-talin with lipid monolayers. A film balance study. FEBS Lett (1993) 0.90
Organization of the functional domains in membrane cytoskeletal protein talin. J Biochem (1995) 0.87
Phospholipid binding of synthetic talin peptides provides evidence for an intrinsic membrane anchor of talin. J Biol Chem (2000) 0.87
Partitioning of amino acids into a model membrane: capturing the interface. J Phys Chem B (2014) 0.84
Sequence-dependent interaction of β-peptides with membranes. J Phys Chem B (2010) 0.82