Potential advantages of acute kidney injury management by mesenchymal stem cells.

PubWeight™: 0.87‹?›

🔗 View Article (PMC 4178265)

Published in World J Stem Cells on November 26, 2014

Authors

Francesca Bianchi1, Elisa Sala1, Chiara Donadei1, Irene Capelli1, Gaetano La Manna1

Author Affiliations

1: Francesca Bianchi, Laboratory of Molecular Biology and Stem Cell Engineering - National Institute of Biostructures and Biosystems, Department of Experimental, Diagnostic and Specialty Medicine, S. Orsola-Malpighi Hospital, University of Bologna, 40138 Bologna, Italy.

Associated clinical trials:

Allogeneic Multipotent Stromal Cell Treatment for Acute Kidney Injury Following Cardiac Surgery | NCT00733876

Mesenchymal Stem Cells In Cisplatin-Induced Acute Renal Failure In Patients With Solid Organ Cancers (CIS/MSC08) | NCT01275612

A Study to Evaluate the Safety and Efficacy of AC607 for the Treatment of Kidney Injury in Cardiac Surgery Subjects (ACT-AKI) | NCT01602328

NCT 01602328

NCT 01275612

Articles citing this

Acute kidney injury following cardiac surgery: current understanding and future directions. Crit Care (2016) 0.99

Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapies. BMC Med (2015) 0.91

Extracellular Vesicles in Renal Diseases: More than Novel Biomarkers? J Am Soc Nephrol (2015) 0.86

Mesenchymal Stem Cell-Based Therapy for Kidney Disease: A Review of Clinical Evidence. Stem Cells Int (2016) 0.83

Endothelial autophagy and Endothelial-to-Mesenchymal Transition (EndoMT) in eEPC treatment of ischemic AKI. J Nephrol (2015) 0.78

Loss of regulatory T cell function on anti-inflammation is correlated with increased risk of acute kidney injury development in patients with primary glomerulonephritis. Int J Clin Exp Med (2015) 0.75

Novel surgical techniques, regenerative medicine, tissue engineering and innovative immunosuppression in kidney transplantation. Arch Med Sci (2016) 0.75

Special Morphological Features at the Interface of the Renal Stem/Progenitor Cell Niche Force to Reinvestigate Transport of Morphogens During Nephron Induction. Biores Open Access (2016) 0.75

Nuclear factor erythroid-2 related factor 2 overexpressed mesenchymal stem cells transplantation, improves renal function, decreases injuries markers and increases repair markers in glycerol-induced Acute kidney injury rats. Iran J Basic Med Sci (2016) 0.75

The effects of glomerular and tubular renal progenitors and derived extracellular vesicles on recovery from acute kidney injury. Stem Cell Res Ther (2017) 0.75

Extracellular vesicles in renal disease. Nat Rev Nephrol (2017) 0.75

An in vitro model of renal inflammation after ischemic oxidative stress injury: nephroprotective effects of a hyaluronan ester with butyric acid on mesangial cells. J Inflamm Res (2017) 0.75

Articles cited by this

Marrow stromal cells as stem cells for nonhematopoietic tissues. Science (1997) 17.06

Mesenchymal stem cells in health and disease. Nat Rev Immunol (2008) 11.14

Acute renal failure. N Engl J Med (1996) 8.83

Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res (2008) 8.49

Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol (2008) 6.91

Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol (2009) 5.01

Update on mechanisms of ischemic acute kidney injury. J Am Soc Nephrol (2006) 4.80

Mesenchymal stem cells: mechanisms of inflammation. Annu Rev Pathol (2011) 3.65

Stromal cells protect against acute tubular injury via an endocrine effect. J Am Soc Nephrol (2007) 3.60

Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury. Am J Physiol Renal Physiol (2007) 3.54

Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury. Nephrol Dial Transplant (2011) 3.49

Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT). Cytotherapy (2013) 3.46

Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. J Am Soc Nephrol (2004) 3.41

Exogenous mesenchymal stem cells localize to the kidney by means of CD44 following acute tubular injury. Kidney Int (2007) 2.75

Acute kidney injury: an increasing global concern. Lancet (2013) 2.61

Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice. Stem Cells (2008) 2.51

Mesenchymal stem cells in acute kidney injury. Annu Rev Med (2008) 2.33

Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance. Mol Ther (2008) 2.25

Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury. PLoS One (2012) 2.23

Insulin-like growth factor-1 sustains stem cell mediated renal repair. J Am Soc Nephrol (2007) 2.02

Mesenchymal stem cells prevent progressive experimental renal failure but maldifferentiate into glomerular adipocytes. J Am Soc Nephrol (2007) 1.87

Adipose-derived mesenchymal stem cell protects kidneys against ischemia-reperfusion injury through suppressing oxidative stress and inflammatory reaction. J Transl Med (2011) 1.75

Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells. Stem Cells Dev (2012) 1.53

Immunological characterization of multipotent mesenchymal stromal cells--The International Society for Cellular Therapy (ISCT) working proposal. Cytotherapy (2013) 1.52

Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury. Stem Cells Dev (2009) 1.41

Acute kidney injury in a Chinese hospitalized population. Blood Purif (2010) 1.41

Bone marrow-derived mesenchymal stem cells repaired but did not prevent gentamicin-induced acute kidney injury through paracrine effects in rats. PLoS One (2012) 1.28

Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements. Tissue Eng Part B Rev (2011) 1.26

Isolation of human mesenchymal stem cells: bone marrow versus umbilical cord blood. Haematologica (2001) 1.25

Kallikrein-modified mesenchymal stem cell implantation provides enhanced protection against acute ischemic kidney injury by inhibiting apoptosis and inflammation. Hum Gene Ther (2008) 1.20

Ex vivo pretreatment with melatonin improves survival, proangiogenic/mitogenic activity, and efficiency of mesenchymal stem cells injected into ischemic kidney. Stem Cells (2008) 1.19

VEGF is a mediator of the renoprotective effects of multipotent marrow stromal cells in acute kidney injury. J Cell Mol Med (2008) 1.14

Microvesicles derived from human Wharton's Jelly mesenchymal stromal cells ameliorate renal ischemia-reperfusion injury in rats by suppressing CX3CL1. Stem Cell Res Ther (2014) 1.14

Human amniotic fluid stem cell preconditioning improves their regenerative potential. Stem Cells Dev (2011) 1.12

A systematic review of preclinical studies on the therapeutic potential of mesenchymal stromal cell-derived microvesicles. Stem Cell Rev (2015) 1.10

Kidney protection and regeneration following acute injury: progress through stem cell therapy. Am J Kidney Dis (2012) 1.09

Role of stem-cell-derived microvesicles in the paracrine action of stem cells. Biochem Soc Trans (2013) 1.07

Mesenchymal stem cells in kidney inflammation and repair. Nephrology (Carlton) (2012) 0.98

Biodistribution of mesenchymal stem cell-derived extracellular vesicles in a model of acute kidney injury monitored by optical imaging. Int J Mol Med (2014) 0.97

A novel strategy to enhance mesenchymal stem cell migration capacity and promote tissue repair in an injury specific fashion. Cell Transplant (2012) 0.95

Cell therapy for kidney injury: different options and mechanisms--mesenchymal and amniotic fluid stem cells. Nephron Exp Nephrol (2014) 0.93

Low serum cultured adipose tissue-derived stromal cells ameliorate acute kidney injury in rats. Cell Transplant (2012) 0.91

Mesenchymal stem cells from rats with chronic kidney disease exhibit premature senescence and loss of regenerative potential. PLoS One (2014) 0.91

Mesenchymal stem cells in renal function recovery after acute kidney injury: use of a differentiating agent in a rat model. Cell Transplant (2010) 0.90

The anti-oxidative role of micro-vesicles derived from human Wharton-Jelly mesenchymal stromal cells through NOX2/gp91(phox) suppression in alleviating renal ischemia-reperfusion injury in rats. PLoS One (2014) 0.90

Neutrophil gelatinase-associated lipocalin increases HLA-G(+)/FoxP3(+) T-regulatory cell population in an in vitro model of PBMC. PLoS One (2014) 0.88

Protective effect and localization by optical imaging of human renal CD133+ progenitor cells in an acute kidney injury model. Physiol Rep (2014) 0.86

Microparticles from kidney-derived mesenchymal stem cells act as carriers of proangiogenic signals and contribute to recovery from acute kidney injury. PLoS One (2014) 0.86

Should publications on mesenchymal stem/progenitor cells include in-process data on the preparation of the cells? Stem Cells Transl Med (2014) 0.85

Renal stem cells in recovery from acute kidney injury. Minerva Urol Nefrol (2006) 0.83

Administration of BMSCs with muscone in rats with gentamicin-induced AKI improves their therapeutic efficacy. PLoS One (2014) 0.81

Maximum efficacy of mesenchymal stem cells in rat model of renal ischemia-reperfusion injury: renal artery administration with optimal numbers. PLoS One (2014) 0.81

Co-culture of bone marrow-derived mesenchymal stem cells overexpressing lipocalin 2 with HK-2 and HEK293 cells protects the kidney cells against cisplatin-induced injury. Cell Biol Int (2014) 0.76