Published in Epigenetics on October 01, 2014
ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration. BMC Cancer (2016) 0.78
Lynch syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression. Hum Mutat (2015) 0.76
Fast, Accurate and Automatic Ancient Nucleosome and Methylation Maps with epiPALEOMIX. Mol Biol Evol (2016) 0.75
Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics (2009) 190.94
TopHat: discovering splice junctions with RNA-Seq. Bioinformatics (2009) 81.13
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell (2010) 23.97
A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol (2010) 22.10
Dynamic regulation of nucleosome positioning in the human genome. Cell (2008) 15.60
Evidence for nucleosome depletion at active regulatory regions genome-wide. Nat Genet (2004) 9.10
Nucleosome positioning and gene regulation: advances through genomics. Nat Rev Genet (2009) 6.50
Determinants of nucleosome organization in primary human cells. Nature (2011) 5.50
Evidence for an instructive mechanism of de novo methylation in cancer cells. Nat Genet (2006) 4.97
Evidence for eviction and rapid deposition of histones upon transcriptional elongation by RNA polymerase II. Mol Cell Biol (2004) 4.06
DNA methylation and cancer. Adv Genet (2010) 3.50
Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island. Cancer Cell (2007) 3.15
Activator control of nucleosome occupancy in activation and repression of transcription. PLoS Biol (2008) 2.29
Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer. PLoS Genet (2010) 2.27
Polycomb-repressed genes have permissive enhancers that initiate reprogramming. Cell (2011) 2.14
H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes. Mol Cell (2010) 1.85
Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer. Proc Natl Acad Sci U S A (2011) 1.82
Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer. Genome Res (2014) 1.63
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes. Proc Natl Acad Sci U S A (2011) 1.51
Genomic aberrations occurring in subsets of serrated colorectal lesions but not conventional adenomas. Cancer Res (2013) 1.42
Unanswered questions about the role of promoter methylation in carcinogenesis. Ann N Y Acad Sci (2003) 1.02
Nucleosomes and the accessibility problem. Trends Genet (2011) 0.96
Discrimination of pseudogene and parental gene DNA methylation using allelic bisulfite sequencing. Methods Mol Biol (2014) 0.93
Regulation of a mammalian gene bearing a CpG island promoter and a distal enhancer. Cell Rep (2013) 0.87
Reassembly of nucleosomes at the MLH1 promoter initiates resilencing following decitabine exposure. PLoS Genet (2013) 0.86
Establishing the clinical utility of epigenetic markers in cancer: many challenges ahead. Epigenomics (2013) 0.78
Inheritance of a cancer-associated MLH1 germ-line epimutation. N Engl J Med (2007) 4.87
Germline epimutation of MLH1 in individuals with multiple cancers. Nat Genet (2004) 4.74
Endoscopic mucosal resection outcomes and prediction of submucosal cancer from advanced colonic mucosal neoplasia. Gastroenterology (2011) 3.13
H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome. Genome Res (2008) 3.09
Needle knife sphincterotomy does not increase the risk of pancreatitis in patients with difficult biliary cannulation. Clin Gastroenterol Hepatol (2013) 2.77
Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome. Mol Cell (2007) 2.69
Current evidence does not support routine adjuvant radiotherapy for rectal cancer. ANZ J Surg (2002) 2.55
Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum. Proc Natl Acad Sci U S A (2003) 2.31
Off-label use of medicines: consensus recommendations for evaluating appropriateness. Med J Aust (2006) 2.29
Response rate or time to progression as predictors of survival in trials of metastatic colorectal cancer or non-small-cell lung cancer: a meta-analysis. Lancet Oncol (2006) 2.17
Large refractory colonic polyps: is it time to change our practice? A prospective study of the clinical and economic impact of a tertiary referral colonic mucosal resection and polypectomy service (with videos). Gastrointest Endosc (2009) 2.13
Endoscopic resection for Barrett's high-grade dysplasia and early esophageal adenocarcinoma: an essential staging procedure with long-term therapeutic benefit. Am J Gastroenterol (2010) 1.99
Detachable nylon loop assisted removal of large clinically significant colonic lipomas. Gastrointest Endosc (2005) 1.87
The target sign: an endoscopic marker for the resection of the muscularis propria and potential perforation during colonic endoscopic mucosal resection. Gastrointest Endosc (2011) 1.76
Trastuzumab and metastatic breast cancer: trastuzumab use in Australia--monitoring the effect of an expensive medicine access program. J Clin Oncol (2007) 1.74
MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma. Clin Cancer Res (2003) 1.71
Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue. Int J Colorectal Dis (2003) 1.69
Population-based molecular screening for Lynch syndrome: implications for personalized medicine. J Clin Oncol (2013) 1.59
Dominantly inherited constitutional epigenetic silencing of MLH1 in a cancer-affected family is linked to a single nucleotide variant within the 5'UTR. Cancer Cell (2011) 1.56
Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. Cancer Res (2009) 1.53
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer. Cancer Res (2012) 1.39
EMR of large, sessile, sporadic nonampullary duodenal adenomas: technical aspects and long-term outcome (with videos). Gastrointest Endosc (2008) 1.39
Needle-knife sphincterotomy: factors predicting its use and the relationship with post-ERCP pancreatitis (with video). Gastrointest Endosc (2009) 1.31
Endoscopic therapy for bile leak based on a new classification: results in 207 patients. Gastrointest Endosc (2004) 1.26
The serrated neoplasia pathway. Pathology (2002) 1.25
Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer. Cancer Res (2007) 1.23
Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis. Clin Cancer Res (2006) 1.23
Epimutations and cancer predisposition: importance and mechanisms. Curr Opin Genet Dev (2010) 1.20
Implementation of novel pyrosequencing assays to screen for common mutations of BRAF and KRAS in a cohort of sporadic colorectal cancers. Diagn Mol Pathol (2009) 1.19
The role of BRCA mutation testing in determining breast cancer therapy. Nat Rev Clin Oncol (2010) 1.18
PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer. Clin Cancer Res (2013) 1.17
Histopathological and clinical evaluation of serrated adenomas of the colon and rectum. Mod Pathol (2003) 1.15
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations. Am J Gastroenterol (2013) 1.12
Methylation of the 3p22 region encompassing MLH1 is representative of the CpG island methylator phenotype in colorectal cancer. Mod Pathol (2010) 1.11
Prophylactic clip closure. Gastrointest Endosc (2013) 1.11
A systematic review and meta-analysis of KRAS status as the determinant of response to anti-EGFR antibodies and the impact of partner chemotherapy in metastatic colorectal cancer. Eur J Cancer (2011) 1.10
MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa. Mod Pathol (2009) 1.10
NKT and MAIT invariant TCRα sequences can be produced efficiently by VJ gene recombination. Immunobiology (2012) 1.09
Identification of 5 novel genes methylated in breast and other epithelial cancers. Mol Cancer (2010) 1.07
Elevated Dnmt3a activity promotes polyposis in Apc(Min) mice by relaxing extracellular restraints on Wnt signaling. Gastroenterology (2009) 1.05
Erasure of MLH1 methylation in spermatozoa-implications for epigenetic inheritance. Nat Genet (2007) 1.04
The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis. Int J Cancer (2013) 1.04
The Wnt signalling pathway is upregulated in an in vitro model of acquired tamoxifen resistant breast cancer. BMC Cancer (2013) 1.02
De novo constitutional MLH1 epimutations confer early-onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one. Int J Cancer (2011) 1.02
The Wnt gatekeeper SFRP4 modulates EMT, cell migration and downstream Wnt signalling in serous ovarian cancer cells. PLoS One (2013) 1.02
Giant laterally spreading tumors of the papilla: endoscopic features, resection technique, and outcome (with videos). Gastrointest Endosc (2010) 0.99
En-bloc resection of multiple type 1 gastric carcinoid tumors by endoscopic multi-band mucosectomy. J Gastroenterol Hepatol (2009) 0.98
The role of hMLH1 methylation in the development of synchronous sporadic colorectal carcinomas. Dis Colon Rectum (2002) 0.97
Giant laterally spreading tumors of the duodenum: endoscopic resection outcomes, limitations, and caveats. Gastrointest Endosc (2012) 0.96
Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa. Cancer Prev Res (Phila) (2012) 0.94
Discrimination of pseudogene and parental gene DNA methylation using allelic bisulfite sequencing. Methods Mol Biol (2014) 0.93
Circumferential location predicts the risk of high-grade dysplasia and early adenocarcinoma in short-segment Barrett's esophagus. Gastrointest Endosc (2012) 0.93
Lack of detectable genetic recombination on the X chromosome during the parthenogenetic production of female and male aphids. Genet Res (2002) 0.92
Silencing and transcriptional properties of the imprinted Airn ncRNA are independent of the endogenous promoter. EMBO J (2008) 0.92
Australian clinical practice guidelines for the diagnosis and management of Barrett's esophagus and early esophageal adenocarcinoma. J Gastroenterol Hepatol (2015) 0.91
A blinded comparison of the safety and efficacy of hot biopsy forceps electrocauterization and conventional snare polypectomy for diminutive colonic polypectomy in a porcine model. Gastrointest Endosc (2012) 0.91
A randomized, double-blind trial of succinylated gelatin submucosal injection for endoscopic resection of large sessile polyps of the colon. Am J Gastroenterol (2010) 0.90
Serum albumin prevents protein aggregation and amyloid formation and retains chaperone-like activity in the presence of physiological ligands. J Biol Chem (2012) 0.90
Wide field endoscopic resection for advanced colonic mucosal neoplasia: current status and future directions. Clin Gastroenterol Hepatol (2012) 0.88
Anti-ErbB-2 monoclonal antibodies and ErbB-2-directed vaccines. Cancer Immunol Immunother (2001) 0.88
Analysis of IgE antibodies from a patient with atopic dermatitis: biased V gene usage and evidence for polyreactive IgE heavy chain complementarity-determining region 3. J Immunol (2002) 0.88
Detection of allelic imbalance in MLH1 expression by pyrosequencing serves as a tool for the identification of germline defects in Lynch syndrome. Fam Cancer (2010) 0.87
Reassembly of nucleosomes at the MLH1 promoter initiates resilencing following decitabine exposure. PLoS Genet (2013) 0.86
A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines. Biol Proced Online (2012) 0.86
Standardizing care in medical oncology: are Web-based systems the answer? Cancer (2009) 0.86
Segregation of autosomes during spermatogenesis in the peach-potato aphid (Myzus persicae) (Sulzer) (Hemiptera: Aphididae). Genet Res (2002) 0.85
Trastuzumab therapy in Australia: which patients with HER2+ metastatic breast cancer are assessed for cardiac function? Breast (2013) 0.83
Structural analysis of the ErbB-2 receptor using monoclonal antibodies: Implications for receptor signalling. Int J Cancer (2003) 0.83
Poor-prognosis estrogen receptor-positive breast cancer identified by histopathologic subclassification. Clin Cancer Res (2008) 0.83
Carbon dioxide insufflation reduces number of postprocedure admissions after endoscopic resection of large colonic lesions: a prospective cohort study. Gastrointest Endosc (2012) 0.82
Mutated in colorectal cancer protein modulates the NFκB pathway. Anticancer Res (2012) 0.82
iTRAQ-based proteomic profiling of breast cancer cell response to doxorubicin and TRAIL. J Proteome Res (2012) 0.81
Minor papilla sphincterotomy for pancreatitis due to pancreas divisum. ANZ J Surg (2008) 0.81
Succinylated gelatin substantially increases en bloc resection size in colonic EMR: a randomized, blinded trial in a porcine model. Gastrointest Endosc (2010) 0.81
Snare tip soft coagulation achieves effective and safe endoscopic hemostasis during wide-field endoscopic resection of large colonic lesions (with videos). Gastrointest Endosc (2013) 0.81
Human papillomavirus (HPV) genotypes in an Australian sample of anal cancers. Int J Cancer (2014) 0.81
Low meprin alpha expression differentiates primary ovarian mucinous carcinoma from gastrointestinal cancers that commonly metastasise to the ovaries. J Clin Pathol (2006) 0.80
FluShuffle and FluResort: new algorithms to identify reassorted strains of the influenza virus by mass spectrometry. BMC Bioinformatics (2012) 0.80
Application of phage display technology to cancer research. Curr Pharm Biotechnol (2002) 0.80
Inactivation of p16INK4a by CpG hypermethylation is not a frequent event in colorectal cancer. J Surg Oncol (2003) 0.79
Severity of initial stent angulation predicts reintervention after successful palliative enteral stenting for malignant luminal obstruction. J Gastroenterol Hepatol (2011) 0.79