Characterization of acute biliary hyperplasia in Fisher 344 rats administered the indole-3-carbinol analog, NSC-743380.

PubWeight™: 0.82‹?›

🔗 View Article (PMID 25448049)

Published in Toxicol Appl Pharmacol on October 28, 2014

Authors

Sandy R Eldridge1, Joseph Covey1, Joel Morris1, Bingliang Fang2, Thomas L Horn3, Karen E Elsass4, John R Hamre5, David L McCormick3, Myrtle A Davis6

Author Affiliations

1: Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, 20892, USA.
2: The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
3: IIT Research Institute, Chicago, IL, 60616, USA.
4: Battelle Columbus, Columbus, OH, 43201, USA.
5: Investigative Toxicology Laboratory, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
6: Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, MD, 20892, USA. Electronic address: myrtledavis@mail.nih.gov.

Articles cited by this

Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms. J Clin Invest (2003) 3.02

Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules. J Clin Invest (1988) 2.11

Dissociation between liver inflammation and hepatocellular damage induced by carbon tetrachloride in myeloid cell-specific signal transducer and activator of transcription 3 gene knockout mice. Hepatology (2010) 1.82

Heterogeneity of the proliferative capacity of rat cholangiocytes after bile duct ligation. Am J Physiol (1998) 1.68

Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis. Gastroenterology (2010) 1.17

Serum gamma glutamyl transferase as a specific indicator of bile duct lesions in the rat liver. Am J Pathol (1984) 1.08

Antitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibition. PLoS One (2011) 1.04

Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cells. Biochem Pharmacol (2012) 1.03

Cholangiocytes and blood supply. World J Gastroenterol (2006) 1.00

Biliary epithelial cell proliferation following alpha-naphthylisothiocyanate (ANIT) treatment: relationship to bile duct obstruction. Fundam Appl Toxicol (1995) 1.00

Time course gene expression using laser capture microscopy-extracted bile ducts, but not hepatic parenchyma, reveals acute alpha-naphthylisothiocyanate toxicity. Toxicol Pathol (2010) 0.86

On-target and off-target-based toxicologic effects. Toxicol Pathol (2012) 0.85